CAS 120796-97-6

grande endotelina 38 humana

Descrição:

O big endotelina-1 (frequentemente referido como big endotelina-38 no contexto da biologia humana) é um peptídeo precursor envolvido na regulação do tônus vascular e da pressão arterial. Faz parte da família das endotelinas, que inclui várias isoformas produzidas por células endoteliais. A substância é caracterizada por sua estrutura molecular relativamente grande, que é clivada para formar peptídeos de endotelina ativos, especificamente endotelina-1, -2 e -3. Esses peptídeos são potentes vasoconstritores e desempenham um papel crucial em vários processos fisiológicos, incluindo a função cardiovascular e o equilíbrio de fluidos. O big endotelina-1 é tipicamente liberado em resposta a vários estímulos, incluindo hipóxia e inflamação, e seus níveis podem ser indicativos de certas condições patológicas, como insuficiência cardíaca e hipertensão pulmonar. O número CAS 120796-97-6 identifica especificamente este peptídeo precursor, que é importante para pesquisas e aplicações clínicas na compreensão da saúde cardiovascular e dos mecanismos de doenças.

Fórmula: C₁₈₉H₂₈₂N₄₈O₅₆S₅

Big Endothelin-1 (human)

CAS: 120796-97-6

Human Big ET-1 comprises residues 53-90 of the endothelin precursor (preproendothelin). Compared to the mature endothelin-1 (hET-1), the peptide show less vasoconstrictor activity in vitro, but similar pressor effects in vivo. Former CAS-number 121014-53-7.

Fórmula: C₁₈₉H₂₈₂N₄₈O₅₆S₅

Pureza: 94.0%

Cor e Forma: White Powder

Peso molecular: 4282.94

Ref: 01-4014579

Big Endothelin 1 (human)

CAS: 120796-97-6

Big Endothelin 1 (human)

Ref: 54-BIBA1032

Big Endothelin-1 (Human, 1-38)

CAS: 120796-97-6

This product has disulfide bonds between Cys1-Cys15 and Cys3-Cys11 and is available as a 0.5mg vial. Big Endothelin-1 (Human, 1-38) is a peptide that is a member of the endothelin family and is part of the 39 amino acids of Big Endothelin-1 which is a precursor of Endothelin-1 (ET-1). ET-1 exhibits vasoconstrictive properties and is an activator of endothelin G-protein coupled receptors. Furthermore ET-1 is produced when inflammation, vascular stress or hypoxia occurs. In vivo Big Endothelin-1 has a greater half life compared to ET-1 and therefore makes it useful to study secretory activity in the endothelial system.
Overall Big Endothelin-1 (Human, 1-38) can be used as a research tool for studying protein interactions, receptor activation and function, and ligand binding. This peptide is also used in pharmacology to study the effects of therapeutic agents on receptor activity and expression.

Fórmula: C₁₈₉H₂₈₂N₄₈O₅₆S₅

Pureza: Min. 95%

Peso molecular: 4,282.9 g/mol

Ref: 3D-PED-4208-V

Big Endothelin-1 (human)

CAS: 120796-97-6

Please enquire for more information about Big Endothelin-1 (human) including the price, delivery time and more detailed product information at the technical inquiry form on this page

Fórmula: C₁₈₉H₂₈₂N₄₈O₅₆S₅

Pureza: Min. 95%

Peso molecular: 4,282.88 g/mol

Ref: 3D-FB110372

Big Endothelin-1 (Human, 1-38)

CAS: 120796-97-6

This product has disulfide bonds between Cys1-Cys15 and Cys3-Cys11 and is available as a 0.1mg vial. Big Endothelin-1 (Human, 1-38) is part of the full lengthed 29 amino acid peptide Big Endothlin-1 which is a precursor peptide of the vasoconstrictorEndothelin-1 (ET-1). ET-1 exhibits vasoconstrictive properties and is an activator of endothelin G-protein coupled receptors. Furthermore ET-1 is produced when inflammation, vascular stress or hypoxia occurs. In vivo Big Endothelin-1 has a greater half life compared to ET-1 and therefore makes it useful to study secretory activity in the endothelial system.
Overall Big Endothelin-1 (Human, 1-38) can be used as a research tool for studying protein interactions, receptor activation and function, and ligand binding. This peptide is also used in pharmacology to study the effects of therapeutic agents on receptor activity and expression.

Fórmula: C₁₈₉H₂₈₂N₄₈O₅₆S₅

Pureza: Min. 95%

Peso molecular: 4,282.9 g/mol

Ref: 3D-PED-4208-S