CAS 1210344-57-2

Ertugliflozina

Descrição:

Ertugliflozina é um medicamento usado principalmente no manejo do diabetes mellitus tipo 2. Pertence à classe de medicamentos conhecidos como inibidores do cotransportador sódio-glicose 2 (SGLT2), que funcionam prevenindo a reabsorção de glicose nos rins, promovendo assim sua excreção na urina e reduzindo os níveis de glicose no sangue. A fórmula química de Ertugliflozina reflete sua estrutura, que inclui um grupo de glicose ligado a um sistema de anel aromático específico. Este composto é caracterizado por sua capacidade de melhorar o controle glicêmico e também pode contribuir para a perda de peso e benefícios cardiovasculares em pacientes diabéticos. Além disso, Ertugliflozina tem sido estudado por seus potenciais efeitos na função renal. Efeitos colaterais comuns podem incluir infecções do trato urinário e infecções micóticas genitais, que estão associadas ao aumento de glicose na urina. Assim como com qualquer medicamento, é essencial que os pacientes consultem profissionais de saúde para obter aconselhamento personalizado e monitoramento enquanto utilizam Ertugliflozina.

Fórmula: C₂₂H₂₅ClO₇

InChI: InChI=1S/C22H25ClO7/c1-2-28-16-6-3-13(4-7-16)9-14-10-15(5-8-17(14)23)22-20(27)18(25)19(26)21(11-24,30-22)12-29-22/h3-8,10,18-20,24-27H,2,9,11-12H2,1H3/t18-,19-,20+,21-,22-/m0/s1

Chave InChI: InChIKey=MCIACXAZCBVDEE-CUUWFGFTSA-N

SMILES: O[C@H]1[C@@]2(O[C@@](CO)(CO2)[C@@H](O)[C@@H]1O)C3=CC(CC4=CC=C(OCC)C=C4)=C(Cl)C=C3

Sinónimos:

• (1S,2S,3S,4R,5S)-5-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol
• 1,6-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-5-C-(hydroxymethyl)-beta-L-idopyranose
• 1,6-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-5-C-(hydroxymethyl)-β-<span class="text-smallcaps">L</span>-idopyranose
• Cc-212
• Mk 8835
• Pf 04971729-00
• Pf-04971729
• β-<span class="text-smallcaps">L</span>-Idopyranose, 1,6-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-5-C-(hydroxymethyl)-
• Ertugliflozin
• β-L-Idopyranose, 1,6-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-5-C-(hydroxymethyl)-
• 1,6-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-5-C-(hydroxymethyl)-β-L-idopyranose
• PF04971729;PF 04971729 (ERTUGLIFLOZIN)
• Ertugliflozin Base
• 1,6-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-5-C-(hydroxymethyl)-beta-L-idopyranose PF-04971729(Ertugliflozin)
• PF-04971729/Ertugliflozin
• (1S,2S,3S,4R,5S)-(2,3,4-TRIS-BENZYLOXY-5-(4-CHLORO-3-(4-ETHOXY-BENZYL)-PHENYL)-68-DIOXA-BICYCLO(3.2.1)OCT-1-YL)-METHANOL
• Ertugliflozin, >=98%
• (1S,2S,3S,4R,5S)-5-(4-chloro-3-(4-ethoxybenzyl)phenyl)-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol
• Ertugliflozin/PF-04971729
• PF-04971729 USP/EP/BP
• CS-186
• ERTUGLIFLOZIN;PF04971729;PF 04971729
• Ertugliflozin : PF 04971729-00
• Leuco methylthioninium
• Ertugliflozin MK-8835

1,6-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-5-C-(hydroxymethyl)-β-L-idopyranose

CAS: 1210344-57-2

Fórmula: C₂₂H₂₅ClO₇

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 436.8827

Ref: IN-DA003AC5

(1S,2S,3S,4R,5S)-5-(4-Chloro-3-(4-Ethoxybenzyl)Phenyl)-1-(Hydroxymethyl)-6,8-Dioxabicyclo[3.2.1]Octane-2,3,4-Triol

CAS: 1210344-57-2

(1S,2S,3S,4R,5S)-5-(4-Chloro-3-(4-Ethoxybenzyl)Phenyl)-1-(Hydroxymethyl)-6,8-Dioxabicyclo[3.2.1]Octane-2,3,4-Triol

Pureza: 98%

Peso molecular: 436.88g/mol

Ref: 54-OR1026211

Ertugliflozin

CAS: 1210344-57-2

Ertugliflozin

Pureza: ≥98%

Peso molecular: 436.88g/mol

Ref: 54-BUP15433

Ertugliflozin

CAS: 1210344-57-2

Fórmula: C₂₂H₂₅ClO₇

Cor e Forma: White To Off-White Solid

Peso molecular: 436.89

Ref: 4Z-E-090001

Ertugliflozin

CAS: 1210344-57-2

PF-04971729 (Ertugliflozin (PF-04971729)) is a potent and selective inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2).

Fórmula: C₂₂H₂₅ClO₇

Pureza: 99.89% - 99.96%

Cor e Forma: Solid

Peso molecular: 436.88

Ref: TM-T4999

Ertugliflozin

Produto Controlado

CAS: 1210344-57-2

Fórmula: C₂₂H₂₅ClO₇

Cor e Forma: Neat

Peso molecular: 436.88

Ref: TR-E635090

Ertugliflozin (PF 04971729)

CAS: 1210344-57-2

Ertugliflozin is a novel, selective, and potent inhibitor of SGLT2. It is being developed for the treatment of type 2 diabetes and associated conditions such as hypertension, dyslipidemia and cardiovascular complications. Ertugliflozin selectively inhibits the renal glucose transporter SGLT2 to reduce urinary glucose excretion. In clinical trials ertugliflozin has been shown to significantly lower HbA1c levels in patients with type 2 diabetes mellitus. The drug was well tolerated in clinical trials with no clinically relevant adverse events observed. This agent has also been shown to decrease blood pressure in patients with type 2 diabetes mellitus and normotensive subjects.

Fórmula: C₂₂H₂₅ClO₇

Pureza: Min. 96 Area-%

Cor e Forma: White Off-White Powder

Peso molecular: 436.88 g/mol

Ref: 3D-FE137670