CAS 121521-90-2

Ácido salvianólico B

Descrição:

Ácido salvianólico B é um composto fenólico derivado principalmente das raízes de Salvia miltiorrhiza, comumente conhecido como Danshen, que é amplamente utilizado na medicina tradicional chinesa. Este composto é conhecido por suas propriedades antioxidantes, anti-inflamatórias e cardioprotetoras. Estruturalmente, apresenta múltiplos grupos hidroxila, contribuindo para sua capacidade de eliminar radicais livres e modular várias vias bioquímicas. Ácido salvianólico B tem sido estudado por seus potenciais efeitos terapêuticos em doenças cardiovasculares, neuroproteção e como um complemento no tratamento do câncer devido à sua capacidade de inibir o crescimento tumoral e a metástase. Além disso, exibe uma variedade de atividades farmacológicas, incluindo efeitos anticoagulantes e a capacidade de melhorar a circulação sanguínea. Sua solubilidade em água e solventes orgânicos varia, o que pode influenciar sua biodisponibilidade e eficácia terapêutica. No geral, Ácido salvianólico B representa uma área significativa de interesse em farmacologia e química de produtos naturais, com pesquisas em andamento destinadas a elucidar seus mecanismos de ação e possíveis aplicações clínicas.

Fórmula: C₃₆H₃₀O₁₆

InChI: InChI=1S/C36H30O16/c37-20-6-1-16(11-24(20)41)13-27(34(45)46)50-29(44)10-5-18-3-9-23(40)33-30(18)31(32(52-33)19-4-8-22(39)26(43)15-19)36(49)51-28(35(47)48)14-17-2-7-21(38)25(42)12-17/h1-12,15,27-28,31-32,37-43H,13-14H2,(H,45,46)(H,47,48)/b10-5+/t27-,28-,31+,32-/m1/s1

Chave InChI: InChIKey=SNKFFCBZYFGCQN-VWUOOIFGSA-N

SMILES: C(O[C@H](CC1=CC(O)=C(O)C=C1)C(O)=O)(=O)[C@H]2C=3C(O[C@@H]2C4=CC(O)=C(O)C=C4)=C(O)C=CC3/C=C/C(O[C@H](CC5=CC(O)=C(O)C=C5)C(O)=O)=O

Sinónimos:

• (2R)-2-({(2E)-3-[(2S,3S)-3-{[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy]carbonyl}-2-(3,4-dihydroxyphenyl)-7-hydroxy-2,3-dihydro-1-benzofuran-4-yl]prop-2-enoyl}oxy)-3-(3,4-dihydroxyphenyl)propanoic acid
• (2R)-2-({(2E)-3-[(2S,3S)-3-{[1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy]carbonyl}-2-(3,4-dihydroxyphenyl)-7-hydroxy-2,3-dihydro-1-benzofuran-4-yl]prop-2-enoyl}oxy)-3-(3,4-dihydroxyphenyl)propanoic acid
• 3-(1-Carboxy-2-(3,4-dihydroxyphenyl)ethyl) 4-(3-(1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy)-3-oxo-1-propenyl)-2-(3,4-dihydroxyphenyl)-2,3-dihydro-7-hydroxy-3-benzofurancarboxylate (2S-(2alpha,3beta(S*),4(E(S*))))-
• 3-Benzofurancarboxylic acid, 4-(3-(1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy)-3-oxo-1-propenyl)-2-(3,4-dihydroxyphenyl)-2,3-dihydro-7-hydroxy-, 3-(1-carboxy-2-(3,4-dihydroxyphenyl)ethyl) ester, (2S-(2alpha,3beta(S*),4(E(S*))))-
• 3-Benzofurancarboxylic acid, 4-[(1E)-3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy]-3-oxo-1-propen-1-yl]-2-(3,4-dihydroxyphenyl)-2,3-dihydro-7-hydroxy-, 3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethyl] ester, (2S,3S)-
• 3-Benzofurancarboxylic acid, 4-[(1E)-3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy]-3-oxo-1-propenyl]-2-(3,4-dihydroxyphenyl)-2,3-dihydro-7-hydroxy-, 3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethyl] ester, (2S,3S)-
• 3-Benzofurancarboxylic acid, 4-[3-[1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy]-3-oxo-1-propenyl]-2-(3,4-dihydroxyphenyl)-2,3-dihydro-7-hydroxy-, 3-[1-carboxy-2-(3,4-dihydroxyphenyl)ethyl] ester, [2S-[2α,3β(S*),4[E(S*)]]]-
• Dan Shen Suan B
• Danfensuan B
• Lithospermate B
• Salvianolate
• Salvianolic acid B
• Zinc 49538628

Salvianolic acid B

CAS: 121521-90-2

Salvianolic acid B analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Fórmula: C₃₆H₃₀O₁₆

Pureza: (HPLC) ≥98%

Cor e Forma: Powder

Peso molecular: 718.63

Ref: 11-4757S

Salvianolic Acid B

CAS: 121521-90-2

Other glycosides, natural or reproduced by synthesis, a

Fórmula: C₃₆H₃₀O₁₆

Cor e Forma: Powder

Peso molecular: 718.15338

Ref: 45-1609818

Salvianolic acid B

CAS: 121521-90-2

Fórmula: C₃₆H₃₀O₁₆

Pureza: 94%

Cor e Forma: Solid

Peso molecular: 718.6138

Ref: IN-DA00811R

Salvianolic Acid B

CAS: 121521-90-2

Salvianolic Acid B

Pureza: 98%

Peso molecular: 718.61g/mol

Ref: 54-OR1026463

Salvianolic acid B

CAS: 121521-90-2

Salvianolic acid B

Pureza: ≥98%

Peso molecular: 718.61g/mol

Ref: 54-BUP06829

Salvianolic Acid B

CAS: 121521-90-2

Fórmula: C₃₆H₃₀O₁₆

Pureza: >98.0%(HPLC)

Cor e Forma: White to Orange to Green powder to crystal

Peso molecular: 718.62

Ref: 3B-A3191

Salvianolic acid B

CAS: 121521-90-2

Fórmula: C₃₆H₃₀O₁₆

Pureza: 95%~99%

Peso molecular: 718.62

Ref: BP-BP1248

Salvianolic acid B

CAS: 121521-90-2

Fórmula: C₃₆H₃₀O₁₆

Pureza: ≥ 95.0%

Cor e Forma: White to off-white powder or solid

Peso molecular: 718.62

Ref: 7W-GY9135

Salvianolic acid b

CAS: 121521-90-2

Oxygen-heterocyclic compound

Fórmula: C₃₆H₃₀O₁₆

Pureza: ≥ 90.0 % (HPLC)

Cor e Forma: Powder

Peso molecular: 718.63

Ref: 5G-89783

Salvianolic Acid B

Produto Controlado

CAS: 121521-90-2

Applications Salvianolic acid A (Sal A) and salvianolic acid B (Sal B) were isolated and purified from the crude extract of Salvia miltiorrhiza. Antioxidant activities of Sal A and Sal B were also evaluated and the ABTS results showed that Sal A and Sal B exhibited high total antioxidant activities, their EC50 values were 1.35 0.00 and 1.43 0.01 .mu.g/mL. This compound always contains a significant amount of residual solvent.
References Lin, T., et al.: Biochem. Pharmacol., 51, 1237 (1996), Abd-Elazem, I., et al.: Antivir. Res., 55, 91 (2002), Ji, X., et al.: Life Sci., 73, 1413 (2003), Lin, Y., et al.: Biochem. Biophys. Res. Commun., 348, 593 (2006),

Fórmula: C₃₆H₃₀O₁₆

Cor e Forma: Neat

Peso molecular: 718.61

Ref: TR-S100820

Salvianolic acid B

CAS: 121521-90-2

Salvianolic acid B is a polyphenolic compound, which is derived from the root of Salvia miltiorrhiza, commonly known as Danshen. It is characterized by its potent antioxidant properties, which function primarily through the scavenging of free radicals and inhibition of lipid peroxidation. The compound contributes to the stabilization of endothelial cells and the prevention of atherosclerosis by modulating various signaling pathways involved in oxidative stress and inflammation.

Fórmula: C₃₆H₃₀O₁₆

Pureza: Min. 98 Area-%

Cor e Forma: Slightly Yellow Powder

Peso molecular: 718.61 g/mol

Ref: 3D-FS09426

Salvianolic acid B

CAS: 121521-90-2

Salvianolic acid B (Dan Shen Suan B) is a water-soluble antioxidant from Salvia miltiorrhiza extract with antiplatelet aggregation and antithrombotic effects.

Fórmula: C₃₆H₃₀O₁₆

Pureza: 99.75% - 99.86%

Cor e Forma: Yellow Solid

Peso molecular: 718.61

Ref: TM-T5725