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CAS 123155-04-4

:

2,3-Di-O-metil-6-O-terc-butil-dimetilsilil β-ciclodextrina

Descrição:
2,3-Di-O-metil-6-O-terc-butil-dimetilsilil β-ciclodextrina é um derivado modificado da β-ciclodextrina, um oligossacarídeo cíclico composto por sete unidades de glicose. Este composto apresenta grupos funcionais específicos que aumentam sua solubilidade e estabilidade, tornando-o útil em várias aplicações, particularmente na entrega e formulação de medicamentos. A presença de dois grupos metóxi nas posições 2 e 3 e um grupo tert-butildimetilsililo na posição 6 altera significativamente suas propriedades químicas, permitindo uma melhor interação com moléculas hidrofóbicas. Essa modificação aumenta a lipofilicidade da ciclodextrina, facilitando a encapsulação de medicamentos pouco solúveis. Além disso, o volumoso grupo sililo fornece proteção estérica, o que pode aumentar a estabilidade do composto sob várias condições. A estrutura única deste composto permite que ele forme complexos de inclusão, tornando-o valioso em aplicações farmacêuticas, como aumentar a biodisponibilidade de ingredientes farmacêuticos ativos. No geral, 2,3-Di-O-metil-6-O-terc-butil-dimetilsilil β-ciclodextrina é caracterizado por sua solubilidade modificada, estabilidade e capacidade de formar complexos com várias moléculas hóspedes.
Fórmula:C98H196O35Si7
InChI:InChI=1S/C98H196O35Si7/c1-92(2,3)134(36,37)113-50-57-64-71(99-22)78(106-29)85(120-57)128-65-58(51-114-135(38,39)93(4,5)6)122-87(80(108-31)72(65)100-23)130-67-60(53-116-137(42,43)95(10,11)12)124-89(82(110-33)74(67)102-25)132-69-62(55-118-139(46,47)97(16,17)18)126-91(84(112-35)76(69)104-27)133-70-63(56-119-140(48,49)98(19,20)21)125-90(83(111-34)77(70)105-28)131-68-61(54-117-138(44,45)96(13,14)15)123-88(81(109-32)75(68)103-26)129-66-59(52-115-136(40,41)94(7,8)9)121-86(127-64)79(107-30)73(66)101-24/h57-91H,50-56H2,1-49H3/t57-,58-,59-,60-,61-,62-,63-,64-,65-,66-,67-,68-,69-,70-,71+,72+,73+,74+,75+,76+,77+,78-,79-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-/m1/s1
Chave InChI:InChIKey=YJLSGORJJHKFEN-CUVGCOKVSA-N
SMILES:C(O[Si](C(C)(C)C)(C)C)[C@@H]1[C@@]2([C@H](OC)[C@@H](OC)[C@](O1)(O[C@@]3([C@@H](CO[Si](C(C)(C)C)(C)C)O[C@@]([C@H](OC)[C@H]3OC)(O[C@@]4([C@@H](CO[Si](C(C)(C)C)(C)C)O[C@@]([C@H](OC)[C@H]4OC)(O[C@@]5([C@@H](CO[Si](C(C)(C)C)(C)C)O[C@](O[C@]6([C@H](OC)[C@@H](OC)[C@@](O[C@]7([C@H](OC)[C@@H](OC)[C@@](O[C@]8([C@H](OC)[C@@H](OC)[C@@](O2)(O[C@@H]8CO[Si](C(C)(C)C)(C)C)[H])[H])(O[C@@H]7CO[Si](C(C)(C)C)(C)C)[H])[H])(O[C@@H]6CO[Si](C(C)(C)C)(C)C)[H])[H])([C@H](OC)[C@H]5OC)[H])[H])[H])[H])[H])[H])[H])[H]
Sinónimos:
  • β-Cyclodextrin, 6A,6B,6C,6D,6E,6F,6G-heptakis-O-[(1,1-dimethylethyl)dimethylsilyl]-2A,2B,2C,2D,2E,2F,2G,3A,3B,3C,3D,3E,3F,3G-tetradeca-O-methyl-
  • 6A,6B,6C,6D,6E,6F,6G-Heptakis-O-[(1,1-dimethylethyl)dimethylsilyl]-2A,2B,2C,2D,2E,2F,2G,3A,3B,3C,3D,3E,3F,3G-tetradeca-O-methyl-β-cyclodextrin
  • Heptakis(6-O-tert-butyldimethylsilyl-2,3-di-O-methyl)-β-cyclodextrin
  • 2,4,7,9,12,14,17,19,22,24,27,29,32,34-Tetradecaoxaoctacyclo[31.2.2.23,6.28,11.213,16.218,21.223,26.228,31]nonatetracontane, β-cyclodextrin deriv.
  • 2,3-Di-O-methyl-6-O-tert-butyldimethylsilyl β-cyclodextrin
  • Heptakis(2,3-di-O-Methyl-6-O-tert-butyldiMethylsilyl)cycloMaltoheptaose.
  • Heptakis(2,3-di-O-Methyl-6-O-tert-butyldiMethylsilyl)-β-cyclodextrin
  • 2,3-Dimethyl-6-tert-butyldimethylsilyl-b-cyclodextrin
Ordenar por
Pureza (%)
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100
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90
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95
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3 produtos.
  • Heptakis(2,3-di-O-methyl-6-O-tert-butyldimethylsilyl)-b-cyclodextrin
    Glentham
    + Info

    Heptakis(2,3-di-O-methyl-6-O-tert-butyldimethylsilyl)-b-cyclodextrin

    CAS:

    Ref: 7W-GC4427

    ne
    A consultar
  • Heptakis(2,3-di-O-methyl-6-O-tert-butyldimethylsilyl)-β-cyclodextrin
    TRC
    + Info

    Heptakis(2,3-di-O-methyl-6-O-tert-butyldimethylsilyl)-β-cyclodextrin

    Produto Controlado
    CAS:
    <p>Applications A β-Cyclodextrin derivative.<br>References Yan, D., et al.: Science, 303, 65 (2004), Gou, P.-F., et al.: Biomacromolecules, 11, 934 (2010),<br></p>
    Fórmula:C98H196O35Si7
    Cor e Forma:White
    Peso molecular:2131.18

    Ref: TR-H281105

    50mg
    170,00€
    100mg
    273,00€
    250mg
    620,00€
  • 2,3-Dimethyl-6-tert-butyldimethylsilyl-b-cyclodextrin
    Biosynth
    + Info

    2,3-Dimethyl-6-tert-butyldimethylsilyl-b-cyclodextrin

    CAS:
    <p>This beta-cyclodextrin (β-CD) derivative is a functionalized cyclic oligosaccharide composed of seven glucose units, characterized by a hydrophilic exterior and a lipophilic cavity (bigger than α-CD and smaller than γ-CDs), which allows it to encapsulate various guest molecules. This structural feature facilitates its use in multiple applications, including pharmaceuticals, food enhancement, and cosmetics. In the pharmaceutical industry, it enhances the solubility and stability of poorly water-soluble drugs, improving their bioavailability and efficacy while also masking unpleasant tastes. The food sector utilizes it as a stabilizer for flavors, colors, and nutrients, extending shelf life by protecting sensitive ingredients from degradation. In cosmetics, it serves as a complexing agent for fragrances and active components, ensuring their stability and controlled release. Its use expands to many other fields, including nanotechnology for drug delivery systems, environmental remediation for extracting organic pollutants, textiles for slow-release fragrances, and analytical chemistry for chiral separation.</p>
    Fórmula:C98H196O35Si7
    Pureza:Min. 95 Area-%
    Cor e Forma:White Off-White Powder
    Peso molecular:2,131.18 g/mol

    Ref: 3D-OH16463

    1g
    1.995,00€
    50mg
    253,00€
    100mg
    430,00€
    250mg
    699,00€
    500mg
    1.131,00€