CAS 1235-82-1

Cloridrato de biperideno

Descrição:

Cloridrato de biperideno é um medicamento anticolinérgico sintético usado principalmente no tratamento da doença de Parkinson e dos sintomas extrapiramidais induzidos por medicamentos. Funciona bloqueando os receptores de acetilcolina, ajudando assim a restaurar o equilíbrio entre dopamina e acetilcolina no sistema nervoso central. Este composto aparece como um pó cristalino branco a off-white e é solúvel em água, tornando-o adequado para administração oral e parenteral. Sua estrutura química inclui um anel de piperidina, que é característico de muitos agentes anticolinérgicos. Cloridrato de biperideno é tipicamente administrado em forma de comprimido ou como solução injetável, e seus efeitos farmacológicos podem incluir redução da rigidez muscular e tremores. Efeitos colaterais comuns podem incluir boca seca, visão turva, constipação e retenção urinária, que são típicos de medicamentos anticolinérgicos. Devido ao seu mecanismo de ação, é importante monitorar os pacientes quanto a possíveis efeitos cognitivos, especialmente na população idosa. No geral, Cloridrato de biperideno desempenha um papel significativo no manejo dos sintomas associados a distúrbios do movimento.

Fórmula: C₂₁H₂₉NO·ClH

InChI: InChI=1S/C21H29NO.ClH/c23-21(19-7-3-1-4-8-19,11-14-22-12-5-2-6-13-22)20-16-17-9-10-18(20)15-17;/h1,3-4,7-10,17-18,20,23H,2,5-6,11-16H2;1H

Chave InChI: InChIKey=RDNLAULGBSQZMP-UHFFFAOYSA-N

SMILES: C(CCN1CCCCC1)(O)(C2C3CC(C2)C=C3)C4=CC=CC=C4.Cl

Sinónimos:

• 1-(Bicyclo[2.2.1]hept-5-en-2-yl)-1-phenyl-3-(piperidin-1-yl)propan-1-ol hydrochloride
• 1-(Bicyclo[2.2.1]hept-5-en-2-yl)-1-phenyl-3-(piperidin-1-yl)propan-1-ol hydrochloride (1:1)
• 1-Bicyclo[2.2.1]Hept-5-En-2-Yl-1-Phenyl-3-Piperidin-1-Ylpropan-1-Ol Hydrochloride
• 1-Bicyclo[2.2.1]hept-5-en-2-yl-1-phenyl-3-piperidin-1-ylpropan-1-olhydrochlorid
• 1-Bicycloheptenyl-1-phenyl-3-piperidinopropanol Hydrochloride
• 1-Piperidinepropanol, .alpha.-bicyclo[2.2.1]hept-5-en-2-yl-.alpha.-phenyl-, hydrochloride
• 1-Piperidinepropanol, alpha-bicyclo[2.2.1]hept-5-en-2-yl-alpha-phenyl-, hydrochloride (1:1)
• 1-Piperidinepropanol, α-5-norbornen-2-yl-α-phenyl-, hydrochloride
• 1-Piperidinepropanol, α-bicyclo[2.2.1]hept-5-en-2-yl-α-phenyl-, hydrochloride
• 1-Piperidinepropanol, α-bicyclo[2.2.1]hept-5-en-2-yl-α-phenyl-, hydrochloride (1:1)
• 1235-82-1
• 214-976-2
• Akineton hydrochloride
• Akinophyl
• Biperidene hydrochloride
• NSC 170950
• NSC 84989
• Tasmolin

Biperiden.HCl, 1mg/ml in Methanol (as free base)

CAS: 1235-82-1

Cor e Forma: Single Solution

Ref: LP-BIP-1918-HC-1LM

BIPERIDEN HYDROCHLORIDE CRS

CAS: 1235-82-1

BIPERIDEN HYDROCHLORIDE CRS

Fórmula: C₂₁H₃₀ClNO

Cor e Forma: Powder

Peso molecular: 347.922

Ref: 41-B1120000

BIPERIDEN HYDROCHLORIDE RS

CAS: 1235-82-1

BIPERIDEN HYDROCHLORIDE RS

Fórmula: C₂₁H₃₀ClNO

Cor e Forma: Powder

Peso molecular: 347.922

Ref: 41-ICRS46476

Biperiden (hydrochloride)

CAS: 1235-82-1

Fórmula: C₂₁H₃₀ClNO

Pureza: 98%

Peso molecular: 347.9220

Ref: IN-DA000KOS

Biperiden HCl (Mixture of Diastereomers)

CAS: 1235-82-1

Fórmula: C₂₁H₂₉NO·HCl

Peso molecular: 311.47 36.46

Ref: 4Z-B-111018

1-(Bicyclo[2.2.1]hept-5-en-2-yl)-1-phenyl-3-(piperidin-1-yl)propan-1-ol hydrochloride

CAS: 1235-82-1

1-(Bicyclo[2.2.1]hept-5-en-2-yl)-1-phenyl-3-(piperidin-1-yl)propan-1-ol hydrochloride

Pureza: 98%

Peso molecular: 347.93g/mol

Ref: 54-OR1073974

Biperiden hydrochloride

CAS: 1235-82-1

Fórmula: C₂₁H₃₀ClNO

Peso molecular: 347.92

Ref: 7W-GP6565

Biperiden Hydrochloride

CAS: 1235-82-1

Biperiden HCl is an anti-Parkinson's drug, blocks M1 receptors, manages all Parkinson's types, and is FDA-approved. Non-toxic at 0.11 mg/kg to rats' cognition.

Fórmula: C₂₁H₃₀ClNO

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 347.92

Ref: TM-T14614

Biperiden Hydrochloride

CAS: 1235-82-1

Fórmula: C₂₁H₂₉NO·ClH

Cor e Forma: Neat

Peso molecular: 347.92

Ref: 86-MM0288.00

Biperiden.HCl

CAS: 1235-82-1

Cor e Forma: Neat

Ref: LP-BIP-1918-HC-10

Biperiden Hydrochloride

CAS: 1235-82-1

Cor e Forma: Neat

Ref: 61-FOR0288.00

Biperiden hydrochloride

CAS: 1235-82-1

Cor e Forma: Neat

Ref: 04-CA10628100

Biperiden Hydrochloride-d5 (Mixture of Diastereomers)

Produto Controlado

CAS: 1235-82-1

Applications Biperiden Hydrochloride-d5 is the isotope labelled analog of Biperiden Hydrochloride (B397825); an antiparkinsonian and non-selective muscarinic receptor antagonist. Biperiden is used for the adjunctive treatment of all forms of Parkinson′s Disease (postencephalitic, idiopathic, and arteriosclerotic) and is also commonly used to improve parkinsonian signs and symptoms related to antipsychotic drug therapy. References Patela, Y., et al.: Talanta, 47, 625 (1998); Bebawy, L., et al: J. Pharm. Biomed. Anal., 20, 663 (1999); Dinc, E., et al.: J. Pharm. Biomed. Anal., 28, 591 (2002)

Fórmula: C₂₁D₅H₂₄NO·HCl

Cor e Forma: Off-White

Peso molecular: 352.953

Ref: TR-B397827

Biperiden HCl - Bio-X ™

Produto Controlado

CAS: 1235-82-1

Biperiden is a muscarinic antagonist drug that is used in the treatment of Parkinson's disease and other conditions. Biperiden binds to the dopamine D2 receptor, which inhibits the release of dopamine from presynaptic neurons. It also possesses nicotinolytic activity.

Fórmula: C₂₁H₂₉NO·HCl

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 347.92 g/mol

Ref: 3D-FB64957

Biperiden hydrochloride

Produto Controlado

CAS: 1235-82-1

Biperiden hydrochloride is an anticholinergic medication, which is a synthetic derivative. It exerts its effects primarily through the central nervous system by blocking acetylcholine receptors. This blockade reduces the activity of acetylcholine, a neurotransmitter, which plays a role in muscle contractions and various neural functions. By antagonizing the muscarinic receptors, Biperiden hydrochloride helps in modulating the balance between neurotransmitters in the brain.

Fórmula: C₂₁H₂₉NO•HCl

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 347.92 g/mol

Ref: 3D-BB183958

Biperiden hydrochloride

Produto Controlado

CAS: 1235-82-1

Biperiden hydrochloride is a potent, centrally acting anticholinergic agent that has been used to treat Parkinson's disease and other extrapyramidal disorders. Biperiden hydrochloride works by blocking the transmission of nerve impulses in the brain by inhibiting acetylcholine at the synapse. It also inhibits dopamine release and blocks postsynaptic dopamine receptors. Biperiden hydrochloride is used in vitro to study the effects of drugs on human serum and urine samples, as well as for diagnostic purposes in vivo. In vitro assays are also conducted to study the effect of drugs on locomotor activity and symptoms in animals. Biperiden hydrochloride can be combined with mianserin hydrochloride or fluorescein angiography to study the function of dopaminergic systems in vivo.

Fórmula: C₂₁H₃₀ClNO

Pureza: Min. 94 Area-%

Peso molecular: 347.93 g/mol

Ref: 3D-J-004957