CAS 1235-82-1
:Cloridrato de biperideno
Descrição:
Cloridrato de biperideno é um medicamento anticolinérgico sintético usado principalmente no tratamento da doença de Parkinson e dos sintomas extrapiramidais induzidos por medicamentos. Funciona bloqueando os receptores de acetilcolina, ajudando assim a restaurar o equilíbrio entre dopamina e acetilcolina no sistema nervoso central. Este composto aparece como um pó cristalino branco a off-white e é solúvel em água, tornando-o adequado para administração oral e parenteral. Sua estrutura química inclui um anel de piperidina, que é característico de muitos agentes anticolinérgicos. Cloridrato de biperideno é tipicamente administrado em forma de comprimido ou como solução injetável, e seus efeitos farmacológicos podem incluir redução da rigidez muscular e tremores. Efeitos colaterais comuns podem incluir boca seca, visão turva, constipação e retenção urinária, que são típicos de medicamentos anticolinérgicos. Devido ao seu mecanismo de ação, é importante monitorar os pacientes quanto a possíveis efeitos cognitivos, especialmente na população idosa. No geral, Cloridrato de biperideno desempenha um papel significativo no manejo dos sintomas associados a distúrbios do movimento.
Fórmula:C21H29NO·ClH
InChI:InChI=1S/C21H29NO.ClH/c23-21(19-7-3-1-4-8-19,11-14-22-12-5-2-6-13-22)20-16-17-9-10-18(20)15-17;/h1,3-4,7-10,17-18,20,23H,2,5-6,11-16H2;1H
Chave InChI:InChIKey=RDNLAULGBSQZMP-UHFFFAOYSA-N
SMILES:C(CCN1CCCCC1)(O)(C2C3CC(C2)C=C3)C4=CC=CC=C4.Cl
Sinónimos:- 1-(Bicyclo[2.2.1]hept-5-en-2-yl)-1-phenyl-3-(piperidin-1-yl)propan-1-ol hydrochloride
- 1-(Bicyclo[2.2.1]hept-5-en-2-yl)-1-phenyl-3-(piperidin-1-yl)propan-1-ol hydrochloride (1:1)
- 1-Bicyclo[2.2.1]Hept-5-En-2-Yl-1-Phenyl-3-Piperidin-1-Ylpropan-1-Ol Hydrochloride
- 1-Bicyclo[2.2.1]hept-5-en-2-yl-1-phenyl-3-piperidin-1-ylpropan-1-olhydrochlorid
- 1-Bicycloheptenyl-1-phenyl-3-piperidinopropanol Hydrochloride
- 1-Piperidinepropanol, .alpha.-bicyclo[2.2.1]hept-5-en-2-yl-.alpha.-phenyl-, hydrochloride
- 1-Piperidinepropanol, alpha-bicyclo[2.2.1]hept-5-en-2-yl-alpha-phenyl-, hydrochloride (1:1)
- 1-Piperidinepropanol, α-5-norbornen-2-yl-α-phenyl-, hydrochloride
- 1-Piperidinepropanol, α-bicyclo[2.2.1]hept-5-en-2-yl-α-phenyl-, hydrochloride
- 1-Piperidinepropanol, α-bicyclo[2.2.1]hept-5-en-2-yl-α-phenyl-, hydrochloride (1:1)
- 1235-82-1
- 214-976-2
- Akineton hydrochloride
- Akinophyl
- Biperidene hydrochloride
- NSC 170950
- NSC 84989
- Tasmolin
- Ver mais sinónimos
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16 produtos.
BIPERIDEN HYDROCHLORIDE CRS
CAS:BIPERIDEN HYDROCHLORIDE CRSFórmula:C21H30ClNOCor e Forma:PowderPeso molecular:347.922BIPERIDEN HYDROCHLORIDE RS
CAS:BIPERIDEN HYDROCHLORIDE RSFórmula:C21H30ClNOCor e Forma:PowderPeso molecular:347.9221-(Bicyclo[2.2.1]hept-5-en-2-yl)-1-phenyl-3-(piperidin-1-yl)propan-1-ol hydrochloride
CAS:1-(Bicyclo[2.2.1]hept-5-en-2-yl)-1-phenyl-3-(piperidin-1-yl)propan-1-ol hydrochloridePureza:98%Peso molecular:347.93g/molBiperiden Hydrochloride
CAS:Biperiden HCl is an anti-Parkinson's drug, blocks M1 receptors, manages all Parkinson's types, and is FDA-approved. Non-toxic at 0.11 mg/kg to rats' cognition.Fórmula:C21H30ClNOPureza:98%Cor e Forma:SolidPeso molecular:347.92Biperiden HCl - Bio-X ™
CAS:Produto ControladoBiperiden is a muscarinic antagonist drug that is used in the treatment of Parkinson's disease and other conditions. Biperiden binds to the dopamine D2 receptor, which inhibits the release of dopamine from presynaptic neurons. It also possesses nicotinolytic activity.Fórmula:C21H29NO·HClPureza:Min. 95%Cor e Forma:PowderPeso molecular:347.92 g/molBiperiden hydrochloride
CAS:Produto ControladoBiperiden hydrochloride is an anticholinergic medication, which is a synthetic derivative. It exerts its effects primarily through the central nervous system by blocking acetylcholine receptors. This blockade reduces the activity of acetylcholine, a neurotransmitter, which plays a role in muscle contractions and various neural functions. By antagonizing the muscarinic receptors, Biperiden hydrochloride helps in modulating the balance between neurotransmitters in the brain.
Fórmula:C21H29NO•HClPureza:Min. 95%Cor e Forma:PowderPeso molecular:347.92 g/molBiperiden hydrochloride
CAS:Produto ControladoBiperiden hydrochloride is a potent, centrally acting anticholinergic agent that has been used to treat Parkinson's disease and other extrapyramidal disorders. Biperiden hydrochloride works by blocking the transmission of nerve impulses in the brain by inhibiting acetylcholine at the synapse. It also inhibits dopamine release and blocks postsynaptic dopamine receptors. Biperiden hydrochloride is used in vitro to study the effects of drugs on human serum and urine samples, as well as for diagnostic purposes in vivo. In vitro assays are also conducted to study the effect of drugs on locomotor activity and symptoms in animals. Biperiden hydrochloride can be combined with mianserin hydrochloride or fluorescein angiography to study the function of dopaminergic systems in vivo.Fórmula:C21H30ClNOPureza:Min. 94 Area-%Peso molecular:347.93 g/molBiperiden Hydrochloride-d5 (Mixture of Diastereomers)
CAS:Produto ControladoApplications Biperiden Hydrochloride-d5 is the isotope labelled analog of Biperiden Hydrochloride (B397825); an antiparkinsonian and non-selective muscarinic receptor antagonist. Biperiden is used for the adjunctive treatment of all forms of Parkinson′s Disease (postencephalitic, idiopathic, and arteriosclerotic) and is also commonly used to improve parkinsonian signs and symptoms related to antipsychotic drug therapy.
References Patela, Y., et al.: Talanta, 47, 625 (1998); Bebawy, L., et al: J. Pharm. Biomed. Anal., 20, 663 (1999); Dinc, E., et al.: J. Pharm. Biomed. Anal., 28, 591 (2002)Fórmula:C21D5H24NO·HClCor e Forma:Off-WhitePeso molecular:352.953
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