CAS 125-69-9

Bromidrato de dextrometorfano

Descrição:

Bromidrato de dextrometorfano é um composto sintético usado principalmente como supressor da tosse em medicamentos de venda livre. É um derivado opioide, especificamente um morfinano, mas não possui as propriedades analgésicas típicas dos opioides. Esta substância atua no sistema nervoso central, direcionando-se especificamente ao centro da tosse no cérebro para reduzir o impulso de tossir. Bromidrato de dextrometorfano é tipicamente administrado na forma de comprimidos, xaropes ou pastilhas e é conhecido por seu relativamente baixo potencial de abuso em comparação com outros supressores da tosse. Fisicamente, é um pó cristalino branco a off-white que é solúvel em água e álcool. O composto geralmente é bem tolerado, mas doses excessivas podem levar a efeitos colaterais como tontura, náusea e, em alguns casos, efeitos dissociativos. É importante usar este medicamento conforme indicado, pois o uso indevido pode levar a sérios riscos à saúde. Além disso, é contraindicado em certas populações, incluindo aqueles que tomam inibidores da monoamina oxidase (IMAO).

Fórmula: C₁₈H₂₅NO·BrH

InChI: InChI=1S/C18H25NO.BrH/c1-19-10-9-18-8-4-3-5-15(18)17(19)11-13-6-7-14(20-2)12-16(13)18;/h6-7,12,15,17H,3-5,8-11H2,1-2H3;1H/t15-,17+,18+;/m1./s1

Chave InChI: InChIKey=MISZALMBODQYFT-URVXVIKDSA-N

SMILES: O(C)C=1C=C2[C@]34[C@@]([C@](CC2=CC1)(N(C)CC3)[H])(CCCC4)[H].Br

Sinónimos:

• (+)-3-Methoxy-17-methyl-morphinan hydrobromide
• (9Alpha,13Alpha,14Alpha)-3-Methoxy-17-Methylmorphinan Hydrobromide
• (9Alpha,13Alpha,14Alpha)-3-Methoxy-17-Methylmorphinan Hydrobromide Hydrate
• 3-Methoxy-17-Methylmorphinan Hydrobromide
• 9α,13α,14α-Morphinan, 3-methoxy-17-methyl-, hydrobromide
• Alpha-dextromethorphan
• Antussan
• Codiphan
• Coldex-D
• Colfed
• Delsym
• Demorphan
• Demorphine
• Destromethorphan hydrobromide
• Detosiv Slow Release
• Dextromethorphan bromide
• Dextromethorphan maleate HBR
• Dextroramin P
• Dormetan
• Dormethan
• Medicon
• Methorate hydrobromide
• Metrorat
• Morphinan, 3-methoxy-17-methyl-, hydrobromide (1:1), (9α,13α,14α)-
• Morphinan, 3-methoxy-17-methyl-, hydrobromide, (9α,13α,14α)-
• Nocuf
• Ro 1-5470
• Romilar
• Tosse Sedativo
• Tusilan
• Tussade
• d-3-Methoxy-N-methylmorphinan hydrobromide
• d-Methorphan hydrobromide

Dextromethorphan hydrobromide

CAS: 125-69-9

It is used as a potentially useful NMDA receptor agonist. it is usually used as central nervous antitussive, cough suppressant. This is one of the most popular ingredients in over-the-counter cold and cough medications. Dextromethorphan hydrobromide may be added to other preparations to help treat

Fórmula: C₁₈H₂₆BrNO

Cor e Forma: White, Crystalline powder

Peso molecular: 352.32

Ref: 02-J61732

Dextromethorphan HBr

CAS: 125-69-9

Fórmula: C₁₈H₂₅NO·HBr

Cor e Forma: White To Off-White Solid

Peso molecular: 271.40 80.91

Ref: 4Z-D-0310

D-Methorphan hydrobromide

Produto Controlado

CAS: 125-69-9

Fórmula: C₁₈H₂₅NO·BrH

Cor e Forma: Neat

Peso molecular: 352.31

Ref: 04-C15053000

Dextromethorphan-13C-d3 HBr

CAS: 125-69-9

Fórmula: C₁₇₁₃CH₂₂D₃NO·HBr

Peso molecular: 261.39 80.91

Ref: 4Z-D-0332

Dextromethorphan hydrobromide

Produto Controlado

CAS: 125-69-9

Dextromethorphan hydrobromide is a drug that has been used to treat cough and cold symptoms. It is also an NMDA receptor antagonist, which blocks the activity of the NMDA receptor. Dextromethorphan hydrobromide is metabolized by the liver into dextrorphan and 3-methoxymorphinan, which are both active metabolites. Dextrorphan is a more potent NMDA receptor antagonist than dextromethorphan. The elimination half-life for dextrorphan is about 2 hours, whereas the elimination half-life for dextromethorphan is about 8 hours. The concentration–time curve for dextrorphan has been shown to be sigmoidal with a long tail, whereas the concentration–time curve for dextromethorphan has been shown to be linear with no long tail. Dextrorphan binds to adenosine A3 receptors in a competitive manner and has been shown

Fórmula: C₁₈H₂₅NO·HBr

Pureza: Min. 95%

Peso molecular: 352.31 g/mol

Ref: 3D-FD146330