CAS 125-71-3

Dextrometorfano

Descrição:

Dextrometorfano (DXM) é um derivado sintético de morfinano usado principalmente como supressor da tosse em medicamentos de venda livre. É classificado como um agente antitussígeno não opioide, o que significa que alivia a tosse sem as propriedades aditivas associadas aos opioides. O DXM atua no sistema nervoso central, direcionando-se especificamente ao receptor sigma-1 e ao receptor NMDA, o que contribui aos seus efeitos supressores da tosse. A substância é tipicamente administrada em várias formulações, incluindo xaropes, comprimidos e pastilhas. Dextrometorfano é geralmente bem tolerado, mas pode causar efeitos colaterais como tontura, náusea e sonolência. Em doses mais altas, pode produzir efeitos dissociativos semelhantes aos dos alucinógenos, levando ao seu potencial de abuso. A estrutura química do DXM inclui um grupo metóxi, que o distingue de outros morfinanos. Seu número CAS, 125-71-3, é um identificador único usado para fins regulatórios e de segurança. No geral, embora o DXM seja eficaz para tratar a tosse, deve ser usado de forma responsável para evitar efeitos adversos e potencial abuso.

Fórmula: C₁₈H₂₅NO

InChI: InChI=1S/C18H25NO/c1-19-10-9-18-8-4-3-5-15(18)17(19)11-13-6-7-14(20-2)12-16(13)18/h6-7,12,15,17H,3-5,8-11H2,1-2H3/t15-,17+,18+/m1/s1

Chave InChI: InChIKey=MKXZASYAUGDDCJ-NJAFHUGGSA-N

SMILES: O(C)C=1C=C2[C@]34[C@@]([C@](CC2=CC1)(N(C)CC3)[H])(CCCC4)[H]

Sinónimos:

• (+)-3-Methoxy-17-methylmorphinan
• (+)-3-methoxy-N-methylmorphinan
• (+)-cis-1,3,4,9,10,10a-hexahydro-6-methoxy-11-methyl-2H-10,4a-iminoethanophenanthrene
• (14Α)-3-Methoxy-17-Methylmorphinan
• (9α,13α,14α)-3-Methoxy-17-methylmorphinan
• 3-Methoxy-17-Methyl-(9Alpha,13Alpha,14Alpha)-Morphinan
• 3-Methoxy-17-methyl-9α,13α,14α-morphinan
• 9α,13α,14α-Morphinan, 3-methoxy-17-methyl-
• Ba 2666
• Benylin DM
• D-1,2,3,9,10,10a-Hexahydro-6-methoxy-11-methyl-4H-10,4a-iminoethanophenanthrene
• D-3-Methoxy-N-methylmorphinan
• DEX
• DXM
• DXM Free Base
• Dextromethorphane
• Dextrometorfano
• Morphinan, 3-methoxy-17-methyl-, (9α,13α,14α)-
• Nodex
• Romilar CF
• d-Methorphan

Dextromethorphan

CAS: 125-71-3

Cor e Forma: Neat

Ref: LP-DEX-873-FB-10

Dextromethorphan, 1mg/ml in Methanol

CAS: 125-71-3

Cor e Forma: Single Solution

Ref: LP-DEX-873-FB-1LM

Dextromethorphan

CAS: 125-71-3

Drugs containing a quinoline or isoquinoline ring-system (whether or not hydrogenated) not further fused

Fórmula: C₁₈H₂₅NO

Cor e Forma: White Light Yellow Powder

Peso molecular: 271.19361

Ref: 45-1180503

Dextromethorphan

CAS: 125-71-3

Applications Dextromethorphan is an antitussive compound showing analgesic properties. Used in cough medication formulations.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Church J. et al.: Can J Physiol Pharmacol., 67, 561 (1989); Carliss, R. et al.: Neurotoxicology., 28, 813 (2007);

Fórmula: C₁₈H₂₅NO

Cor e Forma: Neat

Peso molecular: 271.40

Ref: TR-D299445

N-Nitroso Dextromethorphan

Produto Controlado

CAS: 125-71-3

Applications N-Nitroso Dextromethorphan is an impurity of Dextromethorphan (D299445). Dextromethorphan is an antitussive compound showing analgesic properties. Used in cough medication formulations.
References Church J. et al.: Can J Physiol Pharmacol., 67, 561 (1989); Carliss, R. et al.: Neurotoxicology., 28, 813 (2007);

Fórmula: C₁₇H₂₂N₂O₂

Cor e Forma: Light Yellow

Peso molecular: 286.369

Ref: TR-N839350

Dextromethorphan

Produto Controlado

CAS: 125-71-3

9-alpha,-14-alpha-3-Methoxy-17-methylmorphinan (914) is a drug that is used in the treatment of bowel disease. It has been shown to inhibit the activity of enzymes such as polymerase chain, which is responsible for DNA replication and repair. 914 also inhibits dextromethorphan, an opioid that is used in cough suppressant medications. The effects of 914 on dextromethorphan are seen in human subjects who have been given the drug intravenously or orally. 914 binds to receptors that are found on cells in the brain and spinal cord, which explains its analgesic properties. This drug can be dangerous when taken with nonsteroidal anti-inflammatory drugs because it can cause kidney damage or failure.

Fórmula: C₁₈H₂₅NO

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 271.4 g/mol

Ref: 3D-FM36326

Compound T0262L2(SC)

CAS: 125-71-3

Dextromethorphan is a noncompetitive NMDA receptor antagonist and sigma-1 agonist that was approved by the FDA in 1958 for use as a cough suppressant.Cost-effective and quality-assured.

Fórmula: C₁₈H₂₅NO

Pureza: 99.88%

Cor e Forma: White To Slightly Yellow Crystalline Powder Solid

Peso molecular: 271.3972

Ref: TM-T0262L2

Morphinan, 3-methoxy-17-methyl-, (9α,13α,14α)-

CAS: 125-71-3

Fórmula: C₁₈H₂₅NO

Cor e Forma: Solid

Peso molecular: 271.3972

Ref: IN-DA000MZ9