CAS: 1257044-40-8 - ABT-199

Fórmula: C₄₅H₅₀ClN₇O₇S

InChI: InChI=1S/C45H50ClN7O7S/c1-45(2)15-11-33(39(26-45)31-3-5-34(46)6-4-31)29-51-17-19-52(20-18-51)35-7-9-38(42(24-35)60-36-23-32-12-16-47-43(32)49-28-36)44(54)50-61(57,58)37-8-10-40(41(25-37)53(55)56)48-27-30-13-21-59-22-14-30/h3-10,12,16,23-25,28,30,48H,11,13-15,17-22,26-27,29H2,1-2H3,(H,47,49)(H,50,54)

Chave InChI: InChIKey=LQBVNQSMGBZMKD-UHFFFAOYSA-N

SMILES: O=C(NS(=O)(=O)C1=CC=C(NCC2CCOCC2)C(=C1)N(=O)=O)C3=CC=C(C=C3OC=4C=NC=5NC=CC5C4)N6CCN(CC7=C(C=8C=CC(Cl)=CC8)CC(C)(C)CC7)CC6

Sinónimos:

• 4-[4-[[2-(4-Chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[3-nitro-4-[[(tetrahydro-2H-pyran-4-yl)methyl]amino]phenyl]sulfonyl]-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzamide
• Benzamide, 4-[4-[[2-(4-chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[3-nitro-4-[[(tetrahydro-2H-pyran-4-yl)methyl]amino]phenyl]sulfonyl]-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-
• Gdc-0199
• Rg 7601
• Rg7601
• Venclexta
• Venclyxto
• Venetoclax

Benzamide, 4-[4-[[2-(4-chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[3-nitro-4-[[(tetrahydro-2H-pyran-4-yl)methyl]amino]phenyl]sulfonyl]-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-

CAS: 1257044-40-8

• Fórmula: C₄₅H₅₀ClN₇O₇S
• Pureza: 99%
• Cor e Forma: Solid
• Peso molecular: 868.4392

Venetoclax

CAS: 1257044-40-8

• Fórmula: C₄₅H₅₀ClN₇O₇S
• Cor e Forma: Yellow Solid
• Peso molecular: 868.45

Venetoclax

CAS: 1257044-40-8

Venetoclax (ABT-199) is a selective inhibitor of Bcl-2 (Ki < 0.010 nM), binding over 3 orders …

• Fórmula: C₄₅H₅₀ClN₇O₇S
• Pureza: 98% - 99.96%
• Cor e Forma: Solid
• Peso molecular: 868.44

ABT 199 (>99%)(Venetoclax)

CAS: 1257044-40-8

Applications ABT 199 (>99%) is a potent and selective BCL-2 inhibitor that achieves potent …

• Fórmula: C₄₅H₅₀ClN₇O₇S
• Cor e Forma: Light Yellow To Yellow
• Peso molecular: 868.44

ABT 199 (Venetoclax)

CAS: 1257044-40-8

Applications ABT 199 is a potent and selective BCL-2 inhibitor that achieves potent antitumour activity …

• Fórmula: C₄₅H₅₀ClN₇O₇S
• Cor e Forma: Light Yellow To Yellow
• Peso molecular: 868.44

Venetoclax

CAS: 1257044-40-8

A BCL-2 selective inhibitor with no effect on Bcl-xl and thereby prevents thrombocytopenia. Increased sensitivity …

• Fórmula: C₄₅H₅₀ClN₇O₇S
• Pureza: Min. 98 Area-%
• Cor e Forma: Yellow Powder
• Peso molecular: 868.44 g/mol

ABT-199-D10

CAS: 1257044-40-8

Applications ABT-199-D10 is a deuterized form of ABT 199 (A112430), which is a potent and …

• Fórmula: C₄₅D₁₀H₄₀ClN₇O₇S
• Cor e Forma: Neat
• Peso molecular: 878.5