CAS 12584-58-6
:insulina de pâncreas de porco
Descrição:
insulina de pâncreas de porco, identificado pelo número CAS 12584-58-6, é um hormônio polipeptídico que desempenha um papel crucial no metabolismo e na regulação da glicose no corpo. É composto por 51 aminoácidos e está estruturado como duas cadeias, A e B, ligadas por ligações dissulfeto. Esta forma de insulina é derivada de fontes suínas (porco), que se assemelham de perto à insulina humana em sua sequência de aminoácidos, tornando-a eficaz para uso terapêutico no manejo do diabetes. A substância é tipicamente administrada por injeção devido à sua natureza proteica, que impede que seja eficaz quando tomada por via oral. insulina de pâncreas de porco é caracterizada por sua capacidade de reduzir os níveis de glicose no sangue, facilitando a captação de glicose nas células, promovendo a síntese de glicogênio no fígado e inibindo a gluconeogênese. Também é conhecida por sua meia-vida relativamente curta, necessitando de múltiplas doses ao longo do dia para um controle glicêmico ideal. No geral, esta variante de insulina tem sido um agente terapêutico significativo no tratamento do diabetes, particularmente antes do advento da tecnologia de DNA recombinante que permite a produção de insulina humana.
Fórmula:C256H381N65O76S6
InChI:InChI=1/C256H381N65O76S6/c1-29-131(23)205(313-193(337)104-258)251(391)317-204(130(21)22)247(387)288-159(75-82-200(347)348)217(357)282-156(71-78-189(262)333)221(361)308-183-116-401-402-117-184-242(382)305-178(111-323)239(379)294-162(88-123(7)8)224(364)295-168(95-140-53-61-146(327)62-54-140)227(367)283-154(69-76-187(260)331)218(358)290-161(87-122(5)6)222(362)285-158(74-81-199(345)346)220(360)302-174(101-190(263)334)234(374)298-170(97-142-57-65-148(329)66-58-142)230(370)309-182(241(381)304-176(255(396)397)103-192(265)336)115-400-399-114-181(213(353)272-107-194(338)278-153(72-79-197(341)342)216(356)281-151(51-42-84-270-256(266)267)211(351)271-108-195(339)279-166(93-138-46-36-32-37-47-138)226(366)297-167(94-139-48-38-33-39-49-139)229(369)299-171(98-143-59-67-149(330)68-60-143)237(377)320-208(136(28)326)253(393)321-85-43-52-186(321)245(385)286-152(50-40-41-83-257)214(354)277-134(26)254(394)395)311-249(389)203(129(19)20)316-235(375)164(90-125(11)12)292-228(368)169(96-141-55-63-147(328)64-56-141)296-223(363)160(86-121(3)4)289-209(349)133(25)276-215(355)157(73-80-198(343)344)287-246(386)202(128(17)18)315-236(376)165(91-126(13)14)293-232(372)173(100-145-106-269-120-275-145)301-238(378)177(110-322)280-196(340)109-273-212(352)180(113-398-403-118-185(310-243(183)383)244(384)319-207(135(27)325)252(392)306-179(112-324)240(380)318-206(132(24)30-2)250(390)312-184)307-225(365)163(89-124(9)10)291-231(371)172(99-144-105-268-119-274-144)300-219(359)155(70-77-188(261)332)284-233(373)175(102-191(264)335)303-248(388)201(127(15)16)314-210(350)150(259)92-137-44-34-31-35-45-137/h31-39,44-49,53-68,105-106,119-136,150-186,201-208,322-330H,29-30,40-43,50-52,69-104,107-118,257-259H2,1-28H3,(H2,260,331)(H2,261,332)(H2,262,333)(H2,263,334)(H2,264,335)(H2,265,336)(H,268,274)(H,269,275)(H,271,351)(H,272,353)(H,273,352)(H,276,355)(H,277,354)(H,278,338)(H,279,339)(H,280,340)(H,281,356)(H,282,357)(H,283,367)(H,284,373)(H,285,362)(H,286,385)(H,287,386)(H,288,387)(H,289,349)(H,290,358)(H,291,371)(H,292,368)(H,293,372)(H,294,379)(H,295,364)(H,296,363)(H,297,366)(H,298,374)(H,299,369)(H,300,359)(H,301,378)(H,302,360)(H,303,388)(H,304,381)(H,305,382)(H,306,392)(H,307,365)(H,308,361)(H,309,370)(H,310,383)(H,311,389)(H,312,390)(H,313,337)(H,314,350)(H,315,376)(H,316,375)(H,317,391)(H,318,380)(H,319,384)(H,320,377)(H,341,342)(H,343,344)(H,345,346)(H,347,348)(H,394,395)(H,396,397)(H4,266,267,270)/t131-,132-,133-,134-,135?,136?,150-,151-,152-,153-,154-,155-,156-,157-,158-,159-,160-,161-,162-,163-,164-,165-,166-,167-,168-,169-,170-,171-,172-,173-,174-,175-,176-,177-,178-,179-,180-,181-,182-,183-,184-,185-,186-,201-,202-,203-,204-,205-,206-,207-,208-/m0/s1
Sinónimos:- Insulin From Porcine Pancreas
- Insulin, Zinc, Porcine
- Insulin porcine pancreas
Ordenar por
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100
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50
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90
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95
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100
6 produtos.
INSULIN PORCINE FOR SYSTEM SUITABILITY CRS
CAS:INSULIN PORCINE FOR SYSTEM SUITABILITY CRSFórmula:C256H381N65O76S6Insulin Pork
CAS:Insulin and its saltsFórmula:C256H381N65O76S6Cor e Forma:White Off-White Crystalline PowderPeso molecular:5773.62709Insulin Porcine
CAS:Fórmula:C256H381N65O76S6Pureza:≥ 97.0%Cor e Forma:White lyophilized powderPeso molecular:5777.59Insulin (Pork)
CAS:<p>Insulin is a hormone that regulates the metabolism of glucose in the body. Insulin is produced by beta cells in the pancreas and released into the blood following a meal. The insulin binds to receptors on cells, causing them to take up glucose from blood for energy or storage. When there is insufficient insulin, glucose builds up in the bloodstream and causes an increase in blood sugar levels. Insulin injections are used to control the level of glucose in people with type 1 diabetes and type 2 diabetes who cannot produce insulin themselves or those who need additional insulin due to other conditions such as pancreatitis or liver disease. The most common way of administering insulin is by injection subcutaneously (underneath the skin). The absorption rate varies depending on where it is injected, but it takes approximately 10 minutes for an injection site to become usable again after an injection has been given. The pharmacokinetic properties of insulin are dependent on pH and temperature; it's most stable at pH 7-8 and at low temperatures</p>Fórmula:C256H381N65O76S6Pureza:Min. 95%Peso molecular:5,777.54 g/mol
