CAS 1263-89-4: Sulfato de paromomicina

Descrição: Sulfato de paromomicina é um antibiótico aminoglicosídeo usado principalmente para tratar infecções causadas por certos tipos de bactérias, particularmente em casos de amebíase intestinal e leishmaniose. É derivado da bactéria Streptomyces griseus e funciona inibindo a síntese de proteínas em microrganismos suscetíveis. O composto é caracterizado pela sua capacidade de se ligar à subunidade ribossomal 30S, levando à leitura incorreta do mRNA e, em última análise, interrompendo o crescimento bacteriano. A paromomicina é tipicamente administrada por via oral ou parenteral, dependendo da infecção que está sendo tratada. É conhecida por sua toxicidade relativamente baixa em comparação com outros aminoglicosídeos, embora ainda possa causar efeitos colaterais, como distúrbios gastrointestinais e nefrotoxicidade em alguns casos. A forma sulfato melhora sua solubilidade em água, tornando-a adequada para várias formulações. A paromomicina também está sendo investigada por seu potencial uso no tratamento de infecções multirresistentes, destacando sua importância no campo da terapia antimicrobiana.

Fórmula: C₂₃H₄₅N₅O₁₄·xH₂O₄S

InChI: InChI=1S/C23H45N5O14.H2O4S/c24-2-7-13(32)15(34)10(27)21(37-7)41-19-9(4-30)39-23(17(19)36)42-20-12(31)5(25)1-6(26)18(20)40-22-11(28)16(35)14(33)8(3-29)38-22;1-5(2,3)4/h5-23,29-36H,1-4,24-28H2;(H2,1,2,3,4)/t5-,6+,7+,8-,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23+;/m1./s1

Chave InChI: InChIKey=LJRDOKAZOAKLDU-UDXJMMFXSA-N

SMILES: O=S(=O)(O)O.OCC1OC(OC2C(OC3OC(CO)C(OC4OC(CN)C(O)C(O)C4N)C3O)C(O)C(N)CC2N)C(N)C(O)C1O

Sinónimos:

• (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-alpha-D-glucopyranoside sulfate (1:1)
• (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-β-L-idopyranosyl)-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-α-D-glucopyranoside sulfate (salt)
• (2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-alpha-D-glucopyranoside sulfate (1:1)
• 1600 Antibiotic
• 4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxyhexopyranosyl)-D-lyxofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxyhexopyranoside sulfate (salt)
• <span class="text-smallcaps">D</smallcap>-Streptamine, O-2,6-diamino-2,6-dideoxy-β-<smallcap>L</smallcap>-idopyranosyl-(1→3)-O-β-<smallcap>D</smallcap>-ribofuranosyl-(1→5)-O-[2-amino-2-deoxy-α-<smallcap>D</span>-glucopyranosyl-(1→4)]-2-deoxy-, sulfate (1:?)
• <span class="text-smallcaps">D</smallcap>-Streptamine, O-2,6-diamino-2,6-dideoxy-β-<smallcap>L</smallcap>-idopyranosyl-(1→3)-O-β-<smallcap>D</smallcap>-ribofuranosyl-(1→5)-O-[2-amino-2-deoxy-α-<smallcap>D</span>-glucopyranosyl-(1→4)]-2-deoxy-, sulfate (salt)
• <span class="text-smallcaps">D</smallcap>-Streptamine, O-2-amino-2-deoxy-α-<smallcap>D</smallcap>-glucopyranosyl-(1→4)-O-[O-2,6-diamino-2,6-dideoxy-β-<smallcap>L</smallcap>-idopyranosyl-(1→3)-β-<smallcap>D</span>-ribofuranosyl-(1→5)]-2-deoxy-, sulfate (salt)
• Aminosidin sulfate
• Aminosidin sulphate
• Aminosidine Sulphate
• Aminosidine sulfate
• Aminoxidin
• D-Streptamine, O-2,6-diamino-2,6-dideoxy-β-L-idopyranosyl-(1→3)-O-β-D-ribofuranosyl-(1→5)-O-[2-amino-2-deoxy-α-D-glucopyranosyl-(1→4)]-2-deoxy-, sulfate (salt)
• D-Streptamine, O-2-amino-2-deoxy-α-D-glucopyranosyl-(1→4)-O-[O-2,6-diamino-2,6-dideoxy-β-L-idopyranosyl-(1→3)-β-D-ribofuranosyl-(1→5)]-2-deoxy-, sulfate (1:?)
• D-Streptamine, O-2-amino-2-deoxy-α-D-glucopyranosyl-(1→4)-O-[O-2,6-diamino-2,6-dideoxy-β-L-idopyranosyl-(1→3)-β-D-ribofuranosyl-(1→5)]-2-deoxy-, sulfate (salt)
• Farmiglucin
• Farminosidin
• Fi 5853
• Gabbroral
• Humagel
• Humatin
• Humycin sulfate
• O-2-Amino-2-deoxy-α-D-glucopyranosyl-(1→4)-O-[O-2,6-diamino-2,6-dideoxy-β-L-idopyranosyl-(1→3)-β-D-ribofuranosyl-(1→5)]-2-deoxy-D-streptamine sulfate (salt)
• Paramicina
• Pargonyl
• Paricina
• Paromomycin Sulphate
• Paromomycin Sulphates
• Paromomycin sulfate salt
• Paromomycinsulfate
• Sinosid
• Sulfates De Paromomycine
• Sulfatos De Paromomicina
• D-Streptamine, O-2,6-diamino-2,6-dideoxy-β-L-idopyranosyl-(1→3)-O-β-D-ribofuranosyl-(1→5)-O-[2-amino-2-deoxy-α-D-glucopyranosyl-(1→4)]-2-deoxy-, sulfate (1:?)
• Paromomycin sulfate

Paromomycin Sulfate

CAS: 1263-89-47542-37-2 84420-34-8

• Fórmula: C₂₃H₄₅N₅O₁₄·xH₂SO₄
• Pureza: >92.0%(HPLC)
• Cor e Forma: White to Almost white powder to crystal

Paromomycin sulfate

CAS: 1263-89-4

Paromomycin sulfate salt has been used as a reference compound in antileishmanial activity, RNA-binding ligand …

• Fórmula: C₂₃H₄₇N₅O₁₈S
• Cor e Forma: White to pale cream to pale yellow, Powder
• Peso molecular: 713.71

Paromomycin sulfate RS

CAS: 1263-89-4

• Fórmula: C₂₃H₄₅N₅O₁₄
• Peso molecular: 615.6285

Paromomycin Sulfate

CAS: 1263-89-4

Aminoglycoside antibiotics

• Fórmula: C₂₃H₄₅N₅O₁₄·xH₂SO₄
• Cor e Forma: White Off-White Light Yellow Powder
• Peso molecular: 615.2963

Paromomycin sulfate salt

CAS: 1263-89-4

• Fórmula: C₂₃H₄₇N₅O₁₈S
• Pureza: %
• Cor e Forma: Solid
• Peso molecular: 713.707

Paromomycin Sulfate

CAS: 1263-89-4

Paromomycin Sulfate, an aminoglycoside antibiotic, binds to 30S ribosomes, disrupting protein synthesis and killing bacteria.

• Fórmula: C₂₃H₄₇N₅O₁₈S
• Pureza: 99.73% - 99.86%
• Cor e Forma: Solid
• Peso molecular: 713.71

Paromomycin sulfate salt

CAS: 1263-89-4

• Fórmula: C₂₃H₄₅N₅O₁₄·H₂SO₄
• Cor e Forma: White to off-white powder
• Peso molecular: 713.71

Paromomycin sulphate

CAS: 1263-89-4

• Fórmula: C₂₃H₄₅N₅O₁₄·H₂SO₄
• Pureza: Ph - 6 loss on drying: 3.1% (Typical Value in Batch COA)
• Cor e Forma: white to yellowish powder
• Peso molecular: 713.71g/mol

Paromomycin sulfate

CAS: 1263-89-4

• Fórmula: C₂₃H₄₅N₅O₁₄·H₂O₄S
• Cor e Forma: Off-White
• Peso molecular: 713.71

Paromomycin Sulfate

CAS: 1263-89-4

• Fórmula: C₂₃H₄₅N₅O₁₄·H₂O₄S
• Peso molecular: 615.63 98.07

Paromomycin Sulfate

CAS: 1263-89-4

Stability Hygroscopic Applications an aminogycoside antibiotic designed to fight intestinal infections such as cryptosporidiosis, amoebiasis, …

• Fórmula: C₂₃H₄₅N₅O₁₄·H₂O₄S
• Cor e Forma: Neat
• Peso molecular: 713.71

Paromomycin sulfate, Antibiotic for Culture Media Use Only

CAS: 1263-89-4

Paromomycin sulfate is an antibiotic used for culture media to control bacterial contamination of mediums …

• Fórmula: C₂₃H₄₇N₅O₁₈S
• Pureza: Min. 95.0 Area-%
• Peso molecular: 713.71 g/mol

Paromomycin sulfate

CAS: 1263-89-4

Please enquire for more information about Paromomycin sulfate including the price, delivery time and more …

• Fórmula: C₂₃H₄₅N₅O₁₄·xH₂SO₄
• Pureza: ≥675Μg/Mg(On Dried Basis)
• Cor e Forma: Yellow Powder
• Peso molecular: 615.63 g/mol

Paromomycin Sulfate (PRM)

CAS: 1263-89-4

• Fórmula: C₂₃H₄₅N₅O₁₄·H₂SO₄
• Cor e Forma: White to off-white, Powder
• Peso molecular: 713.17

PAROMOMYCIN SULFATE

CAS: 1263-89-4

• Pureza: 95%
• Peso molecular: 713.7100219726562