CAS 1264-62-6

Eritromicina etilsuccinato

Descrição:

Eritromicina etilsuccinato é um antibiótico pertencente à classe dos macrolídeos, utilizado principalmente para tratar várias infecções bacterianas. É um derivado semissintético da eritromicina, que melhora sua estabilidade e biodisponibilidade. O composto é caracterizado por sua capacidade de inibir a síntese de proteínas bacterianas ao se ligar à subunidade ribossomal 50S, tornando-o eficaz contra uma variedade de bactérias Gram-positivas e algumas Gram-negativas. Eritromicina etilsuccinato é tipicamente administrado por via oral e muitas vezes é formulado como um pró-fármaco, que é convertido em eritromicina no corpo. É conhecido por sua toxicidade e efeitos colaterais relativamente baixos, embora distúrbios gastrointestinais possam ocorrer. A substância é solúvel em solventes orgânicos, mas tem solubilidade limitada em água, o que influencia sua formulação e entrega. Além disso, é importante considerar potenciais interações medicamentosas e padrões de resistência ao usar este antibiótico em ambientes clínicos. No geral, Eritromicina etilsuccinato continua sendo uma opção valiosa no tratamento de infecções, particularmente em pacientes que são alérgicos à penicilina.

Fórmula: C₄₃H₇₅NO₁₆

InChI: InChI=1S/C43H75NO16/c1-15-29-43(11,52)36(48)24(5)33(47)22(3)20-41(9,51)38(25(6)34(26(7)39(50)57-29)59-32-21-42(10,53-14)37(49)27(8)56-32)60-40-35(28(44(12)13)19-23(4)55-40)58-31(46)18-17-30(45)54-16-2/h22-29,32,34-38,40,48-49,51-52H,15-21H2,1-14H3/t22-,23-,24+,25+,26-,27+,28+,29-,32+,34+,35-,36-,37+,38-,40+,41-,42-,43-/m1/s1

Chave InChI: InChIKey=NSYZCCDSJNWWJL-YXOIYICCSA-N

SMILES: O(C(CCC(OCC)=O)=O)[C@H]1[C@H](O[C@@H]2[C@@H](C)[C@H](O[C@H]3C[C@](OC)(C)[C@@H](O)[C@H](C)O3)[C@@H](C)C(=O)O[C@H](CC)[C@@](C)(O)[C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@]2(C)O)O[C@H](C)C[C@@H]1N(C)C

Sinónimos:

• (2R,3S,4R,6S)-4-(dimethylamino)-2-{[(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyl-2,10-dioxooxacyclotetradecan-6-yl]oxy}-6-methyltetrahydro-2H-pyran-3-yl ethyl butanedioate (non-preferred name)
• (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-dimethylamino-3-hydroxy-6-methyl-tetrahydropyran-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyl-tetrahydropyran-2-yl]oxy-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecane-2,10-dione
• 4-(dimethylamino)-2-({14-ethyl-7,12,13-trihydroxy-4-[(5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy]-3,5,7,9,11,13-hexamethyl-2,10-dioxooxacyclotetradecan-6-yl}oxy)-6-methyltetrahydro-2H-pyran-3-yl ethyl butanedioate (non-preferred name)
• 4-Ethoxy-4-Oxo-Butanoate
• Anamycin
• Arpimycin
• Durapaediat
• E-Mycin e
• Eritrocina
• EryPed
• Eryliquid
• Erythro ES
• Erythro-Holz
• Erythrocin ethyl succinate
• Erythromycin Ethly Succinate.
• Erythromycin Ethyl Succinate
• Erythromycin Ethylsuccinate
• Erythromycin, 2′-(ethyl butanedioate)
• Erythromycin, 2′-(ethyl succinate)
• Erythromycin, mono(ethyl succinate) (ester)
• Erythroped
• Esinol
• Evesin
• Monomycin
• Oxacyclotetradecane, erythromycin deriv.
• Paediathrocin
• Pediamycin
• Refkas
• Sigapedil
• Succinic acid, ethyl ester, monoester with erythromycin

Erythromycin ethyl succinate

CAS: 1264-62-6

Erythromycin ethyl succinate

Fórmula: C₄₃H₇₅NO₁₆

Cor e Forma: Off-White

Peso molecular: 862.0527

Ref: 47-798

ERYTHROMYCIN ETHYLSUCCINATE RS

CAS: 1264-62-6

ERYTHROMYCIN ETHYLSUCCINATE RS

Fórmula: C₄₃H₇₅NO₁₆

Peso molecular: 862.0527

Ref: 41-ICRS46470

ERYTHROMYCIN ETHYLSUCCINATE CRS

CAS: 1264-62-6

ERYTHROMYCIN ETHYLSUCCINATE CRS

Fórmula: C₄₃H₇₅NO₁₆

Peso molecular: 862.0527

Ref: 41-E1500000

ERYTHROMYCIN ETHYLSUCCINATE FOR IMPURITY P IDENTIFICATION CRS

CAS: 1264-62-6

ERYTHROMYCIN ETHYLSUCCINATE FOR IMPURITY P IDENTIFICATION CRS

Fórmula: C₄₃H₇₅NO₁₆

Peso molecular: 862.0527

Ref: 41-Y0001845

Erythromycin Ethylsuccinate

CAS: 1264-62-6

Erythromycin and its derivatives; salts thereof

Fórmula: C₄₃H₇₅NO₁₆

Cor e Forma: White Powder

Peso molecular: 861.50859

Ref: 45-1245008

(2S,3R,4S,6R)-4-(dimethylamino)-2-{[(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-3,5,7,9,11,13-hexamethyl-2,10-dioxo-1-oxacyclotetradecan-6-yl]oxy}-6-methyloxan-3-yl 1-ethyl butanedioate

CAS: 1264-62-6

Fórmula: C₄₃H₇₅NO₁₆

Cor e Forma: Solid

Peso molecular: 862.0527

Ref: IN-DA000SQT

Erythromycin ethylsuccinate

CAS: 1264-62-6

Erythromycin ethylsuccinate (EES) is a macrolide antibiotic, produced by Streptomyces erythreus.

Fórmula: C₄₃H₇₅NO₁₆

Pureza: 77% - 98%

Cor e Forma: White Or Slightly Yellow Crystalline Powder White To Yellowish Crystalline Solid

Peso molecular: 862.05

Ref: TM-T0474

Erythromycin ethylsuccinate

CAS: 1264-62-6

Erythromycin ethylsuccinate

Pureza: ≥70%

Peso molecular: 862.05g/mol

Ref: 54-BUP16717

Erythromycin Ethylsuccinate

CAS: 1264-62-6

Erythromycin Ethylsuccinate

Pureza: ≥765IU/mg

Peso molecular: 862.05g/mol

Ref: 54-OR1027491

Erythromycin Ethylsuccinate-13C-d3

CAS: 1264-62-6

Fórmula: C₄₂₁₃CH₇₂D₃NO₁₆

Cor e Forma: White To Off-White Solid

Peso molecular: 866.07

Ref: 4Z-E-2015

Erythromycin Ethylsuccinate

CAS: 1264-62-6

Fórmula: C₄₃H₇₅NO₁₆

Cor e Forma: White To Off-White Solid

Peso molecular: 862.06

Ref: 4Z-E-2040

Erythromycin-ethyl succinate

Produto Controlado

CAS: 1264-62-6

Fórmula: C₄₃H₇₅NO₁₆

Cor e Forma: Neat

Peso molecular: 862.05

Ref: 04-C13203520

Erythromycin Ethylsuccinate-D5

CAS: 1264-62-6

Fórmula: C₄₃H₇₀NO₁₆D₅

Peso molecular: 867.10

Ref: 4Z-E-2014

Erythromycin Ethyl Succinate

CAS: 1264-62-6

Fórmula: C₄₃H₇₅NO₁₆

Peso molecular: 862.05

Ref: ST-EA-CP-E18015

Erythromycin Ethyl Succinate

Produto Controlado

CAS: 1264-62-6

Applications Erythromycin Ethyl Succinate is a derivative of Erythromycin (E649950), an antibiotic.
References Koch, W.L., et al.: Anal. Profiles Drug Subs., 8, 157 (1979); Serisier, D. et al.: J. Am. Med. Assoc., 309, 1206 (2013);

Fórmula: C₄₃H₇₅NO₁₆

Cor e Forma: Off-White

Peso molecular: 862.05

Ref: TR-E649985

Erythromycin Ethyl Succinate-13C,d3

Produto Controlado

CAS: 1264-62-6

Applications Erythromycin Ethyl Succinate-13C,d3 is the deuterated form of Erythromycin Ethyl Succinate (E649985), which is a derivative of Erythromycin (E649950), an antibiotic.
References Koch, W.L., et al.: Anal. Profiles Drug Subs., 8, 157 (1979); Serisier, D. et al.: J. Am. Med. Assoc., 309, 1206 (2013);

Fórmula: CC₄₂D₃H₇₂NO₁₆

Cor e Forma: Neat

Peso molecular: 866.064

Ref: TR-E649986

Erythromycin ethyl succinate

CAS: 1264-62-6

Erythromycin ethyl succinate is an ester prodrug that is formed by the reaction of erythromycin and ethylsuccinic acid. It has a broad spectrum of activity against Gram-positive and Gram-negative bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and Mycobacterium tuberculosis. Erythromycin ethyl succinate is also active against Haemophilus influenzae, Moraxella catarrhalis, Chlamydia pneumoniae, Legionella pneumophila, Helicobacter pylori, Leptospira interrogans, Bordetella pertussis, Rickettsia rickettsii, Borrelia burgdorferi, Coxiella burnetii, and Mycoplasma pneumoniae. Erythromycin ethyl succinate has been shown to be effective in treating streptococcal pharyngitis and tissue infections.

Fórmula: C₄₃H₇₅NO₁₆

Pureza: Min. 95%

Peso molecular: 862.05 g/mol

Ref: 3D-FE170906