CAS 1266231-96-2

N-[(1R)-2,3-Dihydro-3-oxo-1H-inden-1-yl]-2,2,2-trifluoroacetamide

Produto Controlado

CAS: 1266231-96-2

Applications N-[(1R)-2,3-Dihydro-3-oxo-1H-inden-1-yl]-2,2,2-trifluoroacetamide is an intermediate in the synthesis of (3R)-2,3-Dihydro-3-(2-propyn-1-ylamino)-1H-inden-1-one (D449765), which is a building block in the preparation of Rasagiline (R126000), which is a selective irreversible MAO-B inhibitor. Rasagiline is also an Antiparkinsonian agent.
References Rabey, J.M., et al.: Clin. Neuropharmacol., 23, 324 (2000); Glezer, S., et al.: Eur. J. Pharmacol., 472, 173 (2003); Youdim, M.B.H., et al.: Biochem. Pharmacol., 66, 1635 (2003); Chen, J.J., et al.: J. Clin. Pharmacol., 45, 878 (2005)

Fórmula: C₁₁H₈F₃NO₂

Cor e Forma: Neat

Peso molecular: 243.182

Ref: TR-D452523