CAS 126643-37-6

Metil (9S,10R,12R)-2,3,9,10,11,12-hexahidro-10-metoxi-2,9-dimetil-1-oxo-9,12-epoxi-1H-diindolo[1,2,3-fg:3′,2′,1′-kl]pirrolo[3,4-i][1,6]benzodiazocina-10-carboxilato

Descrição:

Metil (9S,10R,12R)-2,3,9,10,11,12-hexahidro-10-metoxi-2,9-dimetil-1-oxo-9,12-epoxi-1H-diindolo[1,2,3-fg:3′,2′,1′-kl]pirrolo[3,4-i][1,6]benzodiazocina-10-carboxilato, com número CAS 126643-37-6, é um composto orgânico complexo caracterizado por sua intrincada estrutura policíclica, que inclui múltiplos anéis fundidos e grupos funcionais. Esta substância apresenta um grupo metóxi, indicando a presença de um grupo funcional metóxi (-OCH3), e uma parte carboxilato, o que sugere propriedades ácidas potenciais. A estereoquímica é definida por configurações específicas em vários centros quirais, contribuindo para sua potencial atividade biológica. O grupo epóxido em sua estrutura pode conferir reatividade, tornando-o um candidato para várias transformações químicas. Dada sua complexidade estrutural, este composto pode exibir propriedades farmacológicas únicas, possivelmente relacionadas às suas interações com alvos biológicos. No entanto, estudos detalhados seriam necessários para elucidar suas características específicas, incluindo solubilidade, estabilidade e potenciais aplicações em química medicinal ou outros campos.

Fórmula: C₂₉H₂₅N₃O₅

InChI: InChI=1/C29H25N3O5/c1-28-29(36-4,27(34)35-3)13-20(37-28)31-18-11-7-5-9-15(18)22-23-17(14-30(2)26(23)33)21-16-10-6-8-12-19(16)32(28)25(21)24(22)31/h5-12,20H,13-14H2,1-4H3/t20-,28+,29+/m1/s1

Chave InChI: InChIKey=QTYMDECKVKSGSM-YMUMJAELSA-N

SMILES: C[C@]12N3C=4C5=C(C6=C(C4C=7C3=CC=CC7)CN(C)C6=O)C=8C(N5[C@](O1)(C[C@@]2(C(OC)=O)OC)[H])=CC=CC8

Sinónimos:

• 9,12-Epoxy-1H-diindolo(1,2,3-fg:3',2',1'-kl)pyrrolo(3,4-i)(1,6)benzodiazocine-10-carboxylic acid, 2,3,9,10,11,12-hexahydro-10-methoxy-2,9-dimethyl-1-oxo-, methyl ester, (9R,10R,12R)-
• 9,12-Epoxy-1H-diindolo(1,2,3-fg:3',2',1'-kl)pyrrolo(3,4-i)(1,6)benzodiazocine-10-carboxylic acid, 2,3,9,10,11,12-hexahydro-10-methoxy-2,9-dimethyl-1-oxo-, methyl ester, (9R-(9alpha,10beta,12alpha))-
• 9,12-Epoxy-1H-diindolo[1,2,3-fg:3′,2′,1′-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid, 2,3,9,10,11,12-hexahydro-10-methoxy-2,9-dimethyl-1-oxo-, methyl ester, (9S,10R,12R)-
• 9,12-Epoxy-1H-diindolo[1,2,3-fg:3′,2′,1′-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid, 2,3,9,10,11,12-hexahydro-10-methoxy-2,9-dimethyl-1-oxo-, methyl ester, [9S-(9α,10β,12α)]-
• 9-Methoxy-9-methoxycarbonyl-8-methyl-2,3,9,10-tetrahydro-8,11-epxoy-1H,8H,11H-2,7b-11a-triazadibenzo(a,g)cycloocta(cde)-trinden-1-one
• Antibiotic KT 5823
• Kt 5823
• Methyl (9S,10R,12R)-2,3,9,10,11,12-hexahydro-10-methoxy-2,9-dimethyl-1-oxo-9,12-epoxy-1H-diindolo[1,2,3-fg:3′,2′,1′-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylate
• methyl (5S,6R,8R)-6-methoxy-5,14-dimethyl-13-oxo-5,6,7,8,14,15-hexahydro-13H-5,8-epoxy-4b,8a,14-triazadibenzo[b,h]cycloocta[1,2,3,4-jkl]cyclopenta[e]-as-indacene-6-carboxylate
• KT5823
• (9S, 10R, 12R)-2,3,9,10,11,12-HEXAHYDRO-10-METHOXY-2,9-DIMETHYL-1-OXO-9,12-EPOXY-1H-DIINDOLO[1,2,3-FG:3',2',1'-KL]PYRROLO[3,4-I][1,6]BENZODIAZOCINE-10-CARBOXYLIC ACID, METHYL ESTER
• KT5823 - CAS 126643-37-6 - Calbiochem
• (9S,10R,12R)-2,3,9,10,11,12-Hexahydro-10-methoxy-2,9-dimethyl-1-oxo-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid, methyl ester
• KT 5283
• 9,12-Epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid, 2,3,9,10,11,12-hexahydro-10-methoxy-2,9-dimethyl-1-oxo-, methyl ester, (9S,10R,12R)-
• PROTEIN KINASE INHIBITOR KT 5823
• (9R)-2,3,9,10,11,12-Hexahydro-10β-methoxy-2,9-dimethyl-1-oxo-9α,12α-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid methyl ester

KT 5823

CAS: 126643-37-6

Fórmula: C₂₉H₂₅N₃O₅

Peso molecular: 495.5259

Ref: IN-DA000T2G

KT5823

CAS: 126643-37-6

KT5823

Cor e Forma: Yellow Lyophilised Powder

Peso molecular: 495.53g/mol

Ref: 54-BIK1004

KT 5823

CAS: 126643-37-6

Fórmula: C₂₉H₂₅N₃O₅

Pureza: ≥ 95.0%

Cor e Forma: White solid

Peso molecular: 495.53

Ref: 7W-GK8618

KT5823

CAS: 126643-37-6

KT5823 is a cGMP-dependent protein kinase (PKG) inhibitor that increases iodide ion uptake by regulating the expression of sodium iodide symporter protein.

Fórmula: C₂₉H₂₅N₃O₅

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 495.53

Ref: TM-T15670

KT 5823

CAS: 126643-37-6

Inhibitor of protein kinase PKG

Fórmula: C₂₉H₂₅N₃O₅

Pureza: Min. 95%

Cor e Forma: Solid

Peso molecular: 495.53 g/mol

Ref: 3D-BK162736