CAS 126766-32-3

metil 4-[(3,4-diclorofenil)acetil]-3-(pirrolidin-1-ilmetil)piperazina-1-carboxilato (2E)-but-2-enedioato

Descrição:

metil 4-[(3,4-diclorofenil)acetil]-3-(pirrolidin-1-ilmetil)piperazina-1-carboxilato (2E)-but-2-enedioato, identificado pelo número CAS 126766-32-3, é um composto orgânico sintético caracterizado por sua complexa estrutura molecular, que inclui um anel de piperazina, um grupo de pirrolidina e um grupo diclorofenila. Este composto normalmente exibe propriedades associadas aos seus grupos funcionais, como a potencial solubilidade em solventes orgânicos e estabilidade moderada em condições padrão. A presença dos anéis de piperazina e pirrolidina sugere possível atividade biológica, tornando-o de interesse na química medicinal, particularmente no desenvolvimento de produtos farmacêuticos. Sua estrutura indica potenciais interações com alvos biológicos, o que pode levar a vários efeitos farmacológicos. Além disso, a síntese do composto envolve múltiplas etapas, destacando sua complexidade e a necessidade de manuseio cuidadoso em ambientes de laboratório. Assim como muitos compostos sintéticos, os dados de segurança e as precauções de manuseio são essenciais devido à potencial toxicidade ou reatividade.

Fórmula: C₁₉H₂₅Cl₂N₃O₃·C₄H₄O₄

InChI: InChI=1S/C19H25Cl2N3O3.C4H4O4/c1-27-19(26)23-8-9-24(15(13-23)12-22-6-2-3-7-22)18(25)11-14-4-5-16(20)17(21)10-14;5-3(6)1-2-4(7)8/h4-5,10,15H,2-3,6-9,11-13H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1+

Chave InChI: InChIKey=ABTNETSDXZBJTE-WLHGVMLRSA-N

SMILES: C(CC1=CC(Cl)=C(Cl)C=C1)(=O)N2C(CN3CCCC3)CN(C(OC)=O)CC2.C(=C/C(O)=O)\C(O)=O

Sinónimos:

• 1-Piperazinecarboxylic acid, 4-[(3,4-dichlorophenyl)acetyl]-3-(1-pyrrolidinylmethyl)-, methyl ester, (2E)-2-butenedioate (1:1)
• 1-Piperazinecarboxylic acid, 4-[(3,4-dichlorophenyl)acetyl]-3-(1-pyrrolidinylmethyl)-, methyl ester, (E)-2-butenedioate (1:1)
• 1-Piperazinecarboxylic acid, 4-[2-(3,4-dichlorophenyl)acetyl]-3-(1-pyrrolidinylmethyl)-, methyl ester, (2E)-2-butenedioate (1:1)
• Gr 89696
• Methyl 4-[(3,4-dichlorophenyl)acetyl]-3-(pyrrolidin-1-ylmethyl)piperazine-1-carboxylate (2E)-but-2-enedioate (1:1)
• 4-([3,4-DICHLOROPHENYL]ACETYL)-3-(1-PYRROLIDINYLMETHYL)-1-PIPERAZINECARBOXYLIC ACID METHYL ESTER FUMARATE
• GR 89696 fumarate salt solid
• 4-((3,4-Dichlorophenyl)acetyl)-3-(1-pyrrolidinylmethyl)-1-piperazinecarboxylicacidmethylesterfumarate
• Methyl 4-(2-(3,4-dichlorophenyl)acetyl)-3-(pyrrolidin-1-ylmethyl)piperazine-1-carboxylate fumarate
• GR 89696 FUMARATE

1-Piperazinecarboxylic acid, 4-[2-(3,4-dichlorophenyl)acetyl]-3-(1-pyrrolidinylmethyl)-, methyl ester, (2E)-2-butenedioate (1:1)

CAS: 126766-32-3

Fórmula: C₂₃H₂₉Cl₂N₃O₇

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 530.3983

Ref: IN-DA000T7X

Methyl 4-(2-(3,4-Dichlorophenyl)Acetyl)-3-(Pyrrolidin-1-Ylmethyl)Piperazine-1-Carboxylate Fumarate

CAS: 126766-32-3

Methyl 4-(2-(3,4-Dichlorophenyl)Acetyl)-3-(Pyrrolidin-1-Ylmethyl)Piperazine-1-Carboxylate Fumarate

Pureza: 98%

Peso molecular: 530.4g/mol

Ref: 54-OR1023356

GR 89696 fumarate

CAS: 126766-32-3

GR 89696 fumarate

Pureza: ≥98%

Peso molecular: 530.4g/mol

Ref: 54-BUP10447

GR 89696 fumarate salt

CAS: 126766-32-3

Fórmula: C₁₉H₂₅Cl₂N₃O₃·C₄H₄O₄

Peso molecular: 530.40

Ref: 7W-GK9421

GR 89696

Produto Controlado

CAS: 126766-32-3

Fórmula: C₁₉H₂₅Cl₂N₃O₃·C₄H₄O₄

Cor e Forma: Neat

Peso molecular: 530.398

Ref: TR-G779535

GR 89696 fumarate salt

CAS: 126766-32-3

GR 89696 is a kappa-opioid receptor agonist that is a racemic mixture of the two enantiomers, S and R. It has high affinity for the human kappa-opioid receptor, with values of 500 nM and 100 nM for the S and R enantiomers, respectively. GR 89696 has been shown to produce antinociception in experimental animals. This effect was blocked by pretreatment with the δ-opioid antagonist naltrindole, but not by pretreatment with the κ-opioid antagonist norbinaltorphimine or the κ/δ-opioid antagonist pentazocine. The drug also inhibits rotarod performance in mice at low doses, which may be due to its sedative effect.
GR 89696 has been shown to inhibit bone cancer cell growth in vitro and in vivo without inducing significant toxicity in healthy cells. The drug also showed efficacy against

Fórmula: C₁₉H₂₅Cl₂N₃O₃·C₄H₄O₄

Pureza: Min. 95%

Peso molecular: 530.4 g/mol

Ref: 3D-BFA76632

GR 89696 fumarate

CAS: 126766-32-3

GR 89696 fumarate is a highly selective κ2 opioid receptor agonist (IC50 = 0.04nM) with anti-pruritchy, anti-injury and neuroprotective effects.

Fórmula: C₂₃H₂₉Cl₂N₃O₇

Pureza: 99.84%

Cor e Forma: Solid

Peso molecular: 530.4

Ref: TM-T22810