CAS 12771-72-1

verruculógeno de penicillium verruculosum

Descrição:

A verruculogen é uma micotoxina produzida pelo fungo Penicillium verruculosum, classificada na categoria de alcaloides indólicos. Este composto é caracterizado por sua estrutura complexa, que inclui uma estrutura bicíclica e múltiplos grupos funcionais, contribuindo para sua atividade biológica. A verruculogen exibe propriedades neurotóxicas, afetando a liberação de neurotransmissores e potencialmente levando a efeitos adversos no sistema nervoso. Foi estudada por suas potenciais implicações na segurança alimentar, pois pode contaminar vários produtos agrícolas. O composto também é de interesse na pesquisa farmacológica devido ao seu mecanismo de ação único e potenciais aplicações terapêuticas. No entanto, sua toxicidade exige manuseio e regulamentação cuidadosos. Em termos de solubilidade, a verruculogen é tipicamente solúvel em solventes orgânicos, o que é comum para muitas micotoxinas. No geral, embora a verruculogen apresente avenidas intrigantes para pesquisa, seu perfil toxicológico sublinha a importância de monitorar e controlar sua presença em produtos alimentares e de ração.

Fórmula: C₂₇H₃₃N₃O₇

InChI: InChI=1S/C27H33N3O7/c1-14(2)11-20-29-18-12-15(35-5)8-9-16(18)21-22(29)19(13-26(3,4)37-36-20)30-24(32)17-7-6-10-28(17)25(33)27(30,34)23(21)31/h8-9,11-12,17,19-20,23,31,34H,6-7,10,13H2,1-5H3/t17-,19-,20+,23-,27+/m0/s1

Chave InChI: InChIKey=LRXYHMMJJCTUMY-GWXUGYLUSA-N

SMILES: C(=C(C)C)[C@@H]1N2C3=C(C=4C2=CC(OC)=CC4)[C@H](O)[C@]5(O)N([C@]3(CC(C)(C)OO1)[H])C(=O)[C@]6(N(C5=O)CCC6)[H]

Sinónimos:

• (5R,10S,10aR,14aS,15bS)-1,10,10a,14,14a,15b-Hexahydro-10,10a-dihydroxy-7-methoxy-2,2-dimethyl-5-(2-methyl-1-propen-1-yl)-5H,12H-3,4-dioxa-5a,11a,15a-triazacyclooct[lm]indeno[5,6-b]fluorene-11,15(2H,13H)-dione
• 10,10a-dihydroxy-7-methoxy-2,2-dimethyl-5-(2-methylprop-1-en-1-yl)-1,10,10a,14,14a,15b-hexahydro-12H-3,4-dioxa-5a,11a,15a-triazacycloocta[1,2,3-lm]indeno[5,6-b]fluorene-11,15(2H,13H)-dione
• 5H,12H-3,4-Dioxa-5a,11a,15a-triazacyclooct[lm]indeno[5,6-b]fluorene-11,15(2H,13H)-dione, 1,10,10a,14,14a,15b-hexahydro-10,10a-dihydroxy-7-methoxy-2,2-dimethyl-5-(2-methyl-1-propen-1-yl)-, (5R,10S,10aR,14aS,15bS)-
• 5H,12H-3,4-Dioxa-5a,11a,15a-triazacyclooct[lm]indeno[5,6-b]fluorene-11,15(2H,13H)-dione, 1,10,10a,14,14a,15b-hexahydro-10,10a-dihydroxy-7-methoxy-2,2-dimethyl-5-(2-methyl-1-propenyl)-, (5R,10S,10aR,14aS,15bS)-
• 5H,12H-3,4-Dioxa-5a,11a,15a-triazacyclooct[lm]indeno[5,6-b]fluorene-11,15(2H,13H)-dione, 1,10,10a,14,14a,15b-hexahydro-10,10a-dihydroxy-7-methoxy-2,2-dimethyl-5-(2-methyl-1-propenyl)-, [5R-(5α,10α,10aα,14aα,15bα)]-
• Na 209A
• TR 1 toxin
• Verruculogen
• Verruculogen TR 1
• Verruculogen, Penicillium verruculosum
• GWIWVUJHTCZBOP-FCXIIMTCSA-N
• tr1
• (5R)-1,10,10a,14,14aα,15bα-Hexahydro-10α,10aα-dihydroxy-7-methoxy-2,2-dimethyl-5α-(2-methyl-1-propenyl)-12H-3,4-dioxa-5a,11a,15a-triazacyclooct[lm]indeno[5,6-b]fluorene-11,15(2H,13H)-dione
• Taste receptor type 1 member 1
• VERRUCULOGEN FROM PENICILLIUM VERRUCULOS
• verruculogen from penicillium*verruculosum
• Verruculogen NA 209A TR 1 toxin
• ANTI-TAS1R1 (CENTER) antibody produced in rabbit
• TRXR1
• TAS1R1
• MGC9145
• Verruculogen solution
• (5R)-2,5,10,10a,11,12,13,14,14aα,15bα-Decahydro-10α,10aα-dihydroxy-7-methoxy-2,2-dimethyl-5α-(2-methyl-1-propenyl)-3,4-dioxa-5a,11a,15a-triaza-1H-cyclooct[lm]indeno[5,6-b]fluorene-11,15-dione
• (5R-(5alpha,10 alpha,10Aalpha,14aalpha,15balpha))-1,10,10A,14,14A,15B-hexahydro-10,10A-dihydroxy-7-methoxy-2,2-dimethyl-5-(2-methyl-1-propenyl)-5H,12H-3,4-dioxa-5A,11A,15A-triaza cyclooct (1m) indeno (5,6-B)fluorene-11,15(2H,13H)-dione
• TR-1TOXIN
• verruculogentr1
• 5H,12H-3,4-Dioxa-5A,11A,15A-triazacyclooct(lm)indeno(5,6-B)fluorene-11,15(2H,13H)-dione, 1,10,10A,14,14A,15B-hexahydro-10,10A-dihydroxy-7-methoxy-2,2-dimethyl-5-(2-methyl-1-propenyl)-,(5R-(5-alpha,10-alpha,10A-alpha,14A-alpha-15B-alpha))-
• GPR70
• yl-5-(2-methyl-1-propenyl)-,(5r-(5-alpha,10-alpha,10a-alpha,14a-alpha-15b-alp
• GRIM-12
• Anti-TAS1R1 (N-terminal) antibody produced in rabbit
• 3h)-dione,1,10,10a,14,14a,15b-hexahydro-10,10a-dihydroxy-7-methoxy-2,2-dimeth
• T1R1
• 5h,12h-3,4-dioxa-5a,11a,15a-triazacyclooct(lm)indeno(5,6-b)fluorene-11,15(2h,1
• VERRUCOLOGEN
• Anti-TAS1R1 (C-terminal) antibody produced in rabbit
• TXNRD1 human

Verruculogen

CAS: 12771-72-1

Fórmula: C₂₇H₃₃N₃O₇

Pureza: 98.89%

Cor e Forma: Brownish. Amorphous solid

Peso molecular: 511.0

Ref: 8R-AD0189

5H,12H-3,4-Dioxa-5a,11a,15a-triazacyclooct[lm]indeno[5,6-b]fluorene-11,15(2H,13H)-dione,1,10,10a,14,14a,15b-hexahydro-10,10a-dihydroxy-7-methoxy-2,2-dimethyl-5-(2-methyl-1-propenyl)-, (5R,10S,10aR,14aS,15bS)-

CAS: 12771-72-1

Fórmula: C₂₇H₃₃N₃O₇

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 511.5668

Ref: IN-DA00VQYN

Verruculogen from Penicillium verruculosum

CAS: 12771-72-1

Verruculogen from Penicillium verruculosum

Fórmula: C₂₇H₃₅N₃O₇

Pureza: By hplc: 97.52% (Typical Value in Batch COA)

Cor e Forma: white powder

Peso molecular: 513.58g/mol

Ref: 54-BIV1002

Verruculogen

CAS: 12771-72-1

Verruculogen, a toxin from Penicillium/Aspergillus, blocks Ca2+-K+ channels and halts mammalian M phase.

Fórmula: C₂₇H₃₃N₃O₇

Pureza: 98%

Cor e Forma: White Powder

Peso molecular: 511.57

Ref: TM-T13297

Verruculogen

CAS: 12771-72-1

Fórmula: C₂₇H₃₃N₃O₇

Pureza: ≥ 95.0%

Cor e Forma: Off-white to brown solid

Peso molecular: 511.6

Ref: 7W-GL5203

Verruculogen

CAS: 12771-72-1

Applications Verruculogen is a mycotoxin and novel mammalian cell cycle inhibitors produced by Aspergillus fumigatus.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Cui, C. et al.: Jour. of Ant., 49(6), 527-533, (1996)

Fórmula: C₂₇H₃₃N₃O₇

Cor e Forma: Neat

Peso molecular: 511.57

Ref: TR-V267190

Verruculogen

CAS: 12771-72-1

Verruculogen is a mycotoxin, which is derived from certain species of fungi, primarily those in the genera Aspergillus and Penicillium. It is synthesized by these fungi during their secondary metabolic processes. As a chemical compound, verruculogen acts by inhibiting calcium channels in nerve cells, disrupts neurotransmitter release, and affects neuronal activity. This mode of action is crucial in understanding its role in toxicology and pharmacology.

Pureza: Min. 95%

Ref: 3D-BV162751