CAS 128-13-2

Ácido ursodesoxicólico

Descrição:

Ácido ursodesoxicólico (UDCA), com o número CAS 128-13-2, é um ácido biliar que ocorre naturalmente no corpo, sintetizado principalmente a partir do colesterol. É caracterizado por suas propriedades hidrofílicas, que o tornam menos tóxico do que outros ácidos biliares. O UDCA é conhecido por sua capacidade de promover a solubilização do colesterol na bile, ajudando assim na prevenção da formação de cálculos biliares de colesterol. Tem sido utilizado terapeuticamente para tratar várias doenças hepáticas, incluindo colangite biliar primária e certas formas de colestase. O composto exibe uma estrutura única, apresentando um grupo hidroxila na posição 7, o que contribui para sua solubilidade e atividade biológica. Além disso, o UDCA possui efeitos anti-inflamatórios e imunomoduladores, tornando-o benéfico no manejo de condições relacionadas ao fígado. Seu mecanismo de ação envolve o aumento do fluxo biliar e a redução da toxicidade dos ácidos biliares, o que pode ser particularmente vantajoso na disfunção hepática. No geral, Ácido ursodesoxicólico é um composto significativo tanto em contextos clínicos quanto bioquímicos, refletindo sua importância na saúde gastrointestinal e no manejo de doenças.

Fórmula: C₂₄H₄₀O₄

InChI: InChI=1/C24H40O4/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10-8-16(25)12-15(23)13-20(22)26/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28)/p-1/t14-,15-,16-,17-,18+,19+,20+,22+,23+,24-/m1/s1

Chave InChI: InChIKey=RUDATBOHQWOJDD-UZVSRGJWSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@](C[C@@H]3O)(C[C@H](O)CC4)[H])(CC1)[H])[H])(CC[C@@]2([C@@H](CCC(O)=O)C)[H])[H]

Sinónimos:

• (3α,5β,7β)-3,7-Dihydroxycholan-24-oic acid
• 17β-(1-Methyl-3-carboxypropyl)etiocholane-3α,7β-diol
• 3α,7β-Dihydroxy-5β-cholan-24-oate
• 3α,7β-Dihydroxy-5β-cholan-24-oic acid
• 3α,7β-Dihydroxy-5β-cholanic acid
• 3α,7β-Dihydroxy-5β-cholanoic acid
• 3α,7β-Dihydroxycholanic acid
• 5β-Cholan-24-oic acid, 3α,7β-dihydroxy-
• 5β-Cholanic acid, 3α,7β-dihydroxy-
• 7β-Hydroxylithocholic acid
• Acide Ursodesoxycholique
• Acido Ursodeoxicolico
• Actigall
• Adursal
• Arsacol
• CHOLON-24-OIC ACID, 3,7-DIHYDROXY-(3α, 5β, 7.β)-
• Cholit-Ursan
• Delursan
• Desocol
• Desol
• Destolit
• Deursil
• Litursol
• Lyeton
• Nsc 683769
• Paptarom
• Solutrat
• Udca
• Urdes
• Urosiol
• Ursacol
• Ursic acid
• Urso
• Ursobilin
• Ursochol
• Ursocholic acid, deoxy-
• Ursocol
• Ursodamor
• Ursodeoxycholic Acid
• Ursodeoxycholsaure
• Ursodesoxycholic acid
• Ursodiol
• Ursofalk
• Ursogall
• Ursolvan
• Ursosan
• (4R)-4-[(3R,5S,7S,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
• (3alpha,5beta,7beta)-3,7-dihydroxycholan-24-oic acid
• 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethanol
• (4R)-4-[(3R,5S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
• (3alpha,5alpha,7beta)-3,7-dihydroxycholan-24-oate
• (3alpha,5beta,7beta)-3,7-dihydroxycholan-24-oate
• 3alpha,7beta-Dihydroxy-6beta-cholan-24-oic acid
• (3alpha,5beta,7beta,8xi,9xi,14xi)-3,7-dihydroxycholan-24-oic acid
• Cholan-24-oic acid, 3,7-dihydroxy-, (3α,5β,7β)-
• (3alpha,5beta,7alpha)-3,7-dihydroxycholan-24-oic acid
• 3,7-Dihydroxycholan-24-oic acid
• 5BETA-CHOLANIC ACID-3ALPHA,7BETA-DIOL
• 3,7-dihydroxy-,(3-alpha,5-beta,7-beta)-cholan-24-oicaci
• 17-beta-(1-methyl-3-carboxypropyl)etiocholane-3-alpha,7-beta-diol
• 3ALPHA, 7BETA-DIOXYCHOLANIC ACID
• 5BETA-CHOLAN-24-OIC ACID-3ALPHA, 7BETA-DIOL
• (6-BETA)-CHOLANIC ACID-(3-ALPHA)-(7-BETA)-DIOL
• UDCS
• 6BETA-CHOLANIC ACID-3A,7BETA-DIOL
• 3ALPHA, 7BETA-DIHYDROXY-5BETA-CHOLANIC ACID
• 3ALPHA,7BETA-DIHYDROXY-5BETA-CHOLAN-24-OIC ACID
• 7BETA-HYDROXYLITHOCHOLIC ACID
• 3-alpha,7-beta-dihydroxy-5-beta-cholan-24-oicaci

Ursodeoxycholic Acid

CAS: 128-13-2

Fórmula: C₂₄H₄₀O₄

Pureza: >98.0%(T)

Cor e Forma: White to Almost white powder to crystaline

Peso molecular: 392.58

Ref: 3B-U0030

Ursodeoxycholic acid, 99%

CAS: 128-13-2

A secondary bile acid This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand tr

Fórmula: C₂₄H₄₀O₄

Pureza: 99%

Cor e Forma: Crystals or powder or crystalline powder, White

Peso molecular: 392.58

Ref: 02-B20490

URSODEOXYCHOLIC ACID CRS

CAS: 128-13-2

URSODEOXYCHOLIC ACID CRS

Ref: 41-U0800000

Ursodeoxycholic acid impurity standard

CAS: 128-13-2

Ursodeoxycholic acid impurity standard

Cor e Forma: Off-White

Ref: 47-1142

Ursodeoxycholic acid

CAS: 128-13-2

Ursodeoxycholic acid

Fórmula: C₂₄H₄₀O₄

Pureza: 99.7%

Cor e Forma: White. To. Off-White

Peso molecular: 392.29266

Ref: 47-706

URSODEOXYCHOLIC ACID FOR SYSTEM SUITABILITY CRS

CAS: 128-13-2

URSODEOXYCHOLIC ACID FOR SYSTEM SUITABILITY CRS

Fórmula: C₂₄H₄₀O₄

Peso molecular: 392.572

Ref: 41-Y0001163

Ursodiol

CAS: 128-13-2

Carboxylic acids w/ alcohol function but w/o other oxygen function and their derivatives, nesoi

Fórmula: C₂₄H₄₀O₄

Cor e Forma: White Off-White Powder

Peso molecular: 392.29266

Ref: 45-1707806

Cholan-24-oic acid, 3,7-dihydroxy-, (3a,5b,7b)-

CAS: 128-13-2

Fórmula: C₂₄H₄₀O₄

Pureza: 99%

Cor e Forma: Solid

Peso molecular: 392.5720

Ref: IN-DA00HRR5

Ursodeoxycholic acid

CAS: 128-13-2

Ursodeoxycholic acid (UDCA) is a potent inhibitor of liver-specific fatty acid transporter 5 (FATP5),inhibits cholesterol absorption. High-Quality, Low-Cost!

Fórmula: C₂₄H₄₀O₄

Pureza: 99.74% - ≥95%

Cor e Forma: White - Almost White Solid Powder

Peso molecular: 392.57

Ref: TM-T0700

Ursodiol (Ursodeoxycholic Acid)

CAS: 128-13-2

Fórmula: C₂₄H₄₀O₄

Cor e Forma: White To Off-White Solid

Peso molecular: 392.58

Ref: 4Z-U-025

Ursodeoxycholic Acid

CAS: 128-13-2

Ursodeoxycholic Acid

Pureza: 98%

Peso molecular: 392.57g/mol

Ref: 54-OR1029332

Ursodeoxycholic acid

CAS: 128-13-2

Fórmula: C₂₄H₄₀O₄

Pureza: 99.0 - 101.0 % (dried basis)

Cor e Forma: White or almost white powder

Peso molecular: 392.56

Ref: 7W-GP1000

Ursodeoxycholic acid

CAS: 128-13-2

Ursodeoxycholic acid

Pureza: ≥95%

Peso molecular: 392.57g/mol

Ref: 54-BUP18898

Ursodeoxycholic acid

CAS: 128-13-2

Fórmula: C₂₄H₄₀O₄

Pureza: 95%~99%

Peso molecular: 392.58

Ref: BP-SBP03888

Ursodeoxycholic Acid

CAS: 128-13-2

Cor e Forma: Neat

Ref: 86-MM0836.00

Ursodeoxycholic Acid

CAS: 128-13-2

Applications Used as an anticholelithogenic. Epimer with Chenodiol with respect to the hydroxyl group at C7.
References Tint, G.S., et al.: Gastroenterology, 91, 1007 (1986), Poupon, R.E, et al.: N. Engl. J. Med., 324, 1548 (1991), MacKenzie, P., et al.: J. Biol. Chem., 283, 36205 (2008),

Fórmula: C₂₄H₄₀O₄

Cor e Forma: White To Off-White

Peso molecular: 392.57

Ref: TR-U850000

Ursodeoxycholic acid

CAS: 128-13-2

Pureza: 98.0%

Cor e Forma: Solid, White powder

Peso molecular: 392.5799865722656

Ref: 10-F095820

Ursodeoxycholic acid

Produto Controlado

CAS: 128-13-2

Ursodeoxycholic acid is a secondary bile acid, which is derived from the metabolism of primary bile acids by intestinal bacteria. It modifies the composition of bile and reduces the absorption of cholesterol in the gastrointestinal tract by decreasing the cholesterol saturation of bile. This leads to a solubilization of cholesterol gallstones, making it an essential therapeutic agent in the management of cholesterol gallstone disease.

Fórmula: C₂₄H₄₀O₄

Cor e Forma: Powder

Peso molecular: 392.57 g/mol

Ref: 3D-FU09676

Ursodeoxycholic acid

Produto Controlado

CAS: 128-13-2

Ursodeoxycholic acid is a naturally occurring bile acid, which is synthesized in the liver from cholesterol. It functions primarily to reduce cholesterol absorption in the intestine and dissolve cholesterol gallstones. This mechanism involves changing the composition of bile and reducing the cholesterol saturation in bile, which reduces micellar cholesterol and bile acid pool size, limiting stone formation.

Fórmula: C₂₄H₄₀O₄

Pureza: Min. 98 Area-%

Peso molecular: 392.58 g/mol

Ref: 3D-U-9000

Ursodeoxycholic Acid (UDCS) extrapure, 99%

CAS: 128-13-2

Fórmula: C₂₄H₄₀O₄

Pureza: min. 99.5%

Cor e Forma: White to off-white, Crystalline powder, Clear, Colourless to pale yellow

Peso molecular: 392.57

Ref: SR-50178