CAS 128517-07-7

(1S,4Z,7S,10S,11E,20R)-4-etilideno-7,20-dipropan-2-il-9-oxa-15,16-ditia-3,6,18,21-tetrazabiciclo[8.7.6]tricos-11-eno-2,5,8,19,22-pentona

Descrição:

A substância química com o nome "(1S,4Z,7S,10S,11E,20R)-4-etilideno-7,20-dipropan-2-il-9-oxa-15,16-ditia-3,6,18,21-tetrazabiciclo[8.7.6]tricos-11-eno-2,5,8,19,22-pentona" e número CAS "128517-07-7" é um composto orgânico complexo caracterizado por sua estrutura bicíclica única, que incorpora múltiplos grupos funcionais, incluindo moieties oxo e thia. A estereoquímica indicada pelas designações (S) e (Z) sugere arranjos espaciais específicos de átomos, que podem influenciar significativamente a reatividade e interações do composto. A presença de múltiplos grupos alquilo, como etilideno e dipropan-2-il, contribui para suas características hidrofóbicas, enquanto a estrutura bicíclica pode conferir rigidez à molécula. Este composto provavelmente exibirá propriedades químicas interessantes, incluindo potencial atividade biológica, devido à sua estrutura intrincada. Suas aplicações podem abranger vários campos, incluindo farmacêuticos e ciência dos materiais, embora os usos específicos dependam de mais pesquisas sobre suas propriedades e comportamento em diferentes ambientes.

Fórmula: C₂₄H₃₆N₄O₆S₂

InChI: InChI=1/C24H36N4O6S2/c1-6-16-21(30)28-20(14(4)5)24(33)34-15-9-7-8-10-35-36-12-17(22(31)25-16)26-23(32)19(13(2)3)27-18(29)11-15/h6-7,9,13-15,17,19-20H,8,10-12H2,1-5H3,(H,25,31)(H,26,32)(H,27,29)(H,28,30)/b9-7+,16-6-/t15-,17+,19+,20-/m0/s1

Sinónimos:

• Fr 901228
• Romidepsin
• (1R,4S,7Z,10S,16E,21R)-7-ethylidene-4,21-bis(1-methylethyl)-2-oxa-12,13-dithia-5,8,20,23-tetraazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone

Cyclo[(2Z)-2-amino-2-butenoyl-L-valyl-(3S,4E)-3-hydroxy-7-mercapto-4-heptenoyl-D-valyl-D-cysteinyl], cyclic (3→5)-disulfide

CAS: 128517-07-7

Fórmula: C₂₄H₃₆N₄O₆S₂

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 540.6958

Ref: IN-DA000Y5C

Romidepsin

CAS: 128517-07-7

Romidepsin

Pureza: ≥98%

Peso molecular: 540.7g/mol

Ref: 54-BUP04661

Romidepsin

CAS: 128517-07-7

Fórmula: C₂₄H₃₆N₄O₆S₂

Peso molecular: 540.69

Ref: 4Z-R-160001

Romidepsin

CAS: 128517-07-7

Romidepsin (NSC-630176), an IV histone deacetylase inhibitor, treats refractory cutaneous/peripheral T-cell lymphomas.

Fórmula: C₂₄H₃₆N₄O₆S₂

Pureza: 99.4% - 99.94%

Cor e Forma: Solid

Peso molecular: 540.7

Ref: TM-T6006

Romidepsin

Produto Controlado

CAS: 128517-07-7

Applications Romidepsin is a histone deacetylase inhibitor that can alter chromatin structure and gene transcription leading to multiple changes in cellular protein production. This may result in cell cycle arrest and tumor growth inhibition. Romidepsin has shown anti-proliferative activity in vitro against multiple mouse and human tumor cell lines and in vivo in human tumor xenograft models. Romidepsin can be administered with a second agent, such as a cytotoxic agent, a steroidal agent, a proteasome inhibitor, or a kinase inhibitor.
References Ueda, H., et al.: J. Antibiot., 47, 301 (1994), Weidle, U., et al.: Anticancer Res., 20, 1471 (2000), Kitazono, M., et al.: Cancer Res., 61, 6328 (2001), Sandor, V., et al.: Clin. Cancer Res., 8, 718 (2002),

Fórmula: C₂₄H₃₆N₄O₆S₂

Cor e Forma: White To Off-White

Peso molecular: 540.70

Ref: TR-R425060

Romidepsin

CAS: 128517-07-7

Natural anti-cancer agent; inhibitor of histone deacetylases

Fórmula: C₂₄H₃₆N₄O₆S₂

Pureza: Min. 95 Area-%

Cor e Forma: White Powder

Peso molecular: 540.7 g/mol

Ref: 3D-FR10656

Romidepsin - Bio-X ™

CAS: 128517-07-7

This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

Fórmula: C₂₄H₃₆N₄O₆S₂

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 540.7 g/mol

Ref: 3D-BR300116

Romidepsin

CAS: 128517-07-7

Pureza: 98%

Peso molecular: 540.69

Ref: 10-F979349

Romidepsin-d8

Produto Controlado

CAS: 128517-07-7

Applications Labelled Romidepsin (R425060). Romidepsin is a histone deacetylase inhibitor that can alter chromatin structure and gene transcription leading to multiple changes in cellular protein production. This may result in cell cycle arrest and tumor growth inhibition. Romidepsin has shown anti-proliferative activity in vitro against multiple mouse and human tumor cell lines and in vivo in human tumor xenograft models. Romidepsin can be administered with a second agent, such as a cytotoxic agent, a steroidal agent, a proteasome inhibitor, or a kinase inhibitor.
References Ueda, H., et al.: J. Antibiot., 47, 301 (1994), Weidle, U., et al.: Anticancer Res., 20, 1471 (2000), Kitazono, M., et al.: Cancer Res., 61, 6328 (2001), Sandor, V., et al.: Clin. Cancer Res., 8, 718 (2002),

Fórmula: C₂₄D₈H₂₈N₄O₆S₂

Cor e Forma: Neat

Peso molecular: 548.745

Ref: TR-R425062