CAS 130-61-0
:Cloridrato de tioridazina
Descrição:
Cloridrato de tioridazina é um medicamento antipsicótico usado principalmente para tratar a esquizofrenia e outros transtornos psicóticos. Pertence à classe de compostos fenotiazínicos, que são caracterizados por uma estrutura de três anéis que inclui um átomo de enxofre. A tioridazina atua principalmente como um antagonista da dopamina, bloqueando os receptores de dopamina no cérebro, o que ajuda a aliviar os sintomas da psicose. A forma de sal hidroclorídrico melhora sua solubilidade e estabilidade. Em termos de características físicas, Cloridrato de tioridazina é tipicamente um pó cristalino branco a branco sujo. É solúvel em água e álcool, com um ponto de fusão relativamente baixo. O composto pode apresentar efeitos colaterais, incluindo sedação, efeitos anticolinérgicos e potenciais problemas cardiovasculares, exigindo monitoramento cuidadoso durante o tratamento. Além disso, a tioridazina tem sido associada a um risco de prolongamento do QT, o que pode levar a distúrbios graves do ritmo cardíaco. Assim como qualquer medicamento, é essencial usar Cloridrato de tioridazina sob a orientação de um profissional de saúde, considerando seus benefícios terapêuticos e riscos potenciais.
Fórmula:C21H26N2S2·ClH
InChI:InChI=1S/C21H26N2S2.ClH/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23;/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3;1H
Chave InChI:InChIKey=NZFNXWQNBYZDAQ-UHFFFAOYSA-N
SMILES:C(CC1N(C)CCCC1)N2C=3C(SC=4C2=CC=CC4)=CC=C(SC)C3.Cl
Sinónimos:- 10-(2-(1-Methyl-2-Piperidinyl)Ethyl)-2-(Methylthio)-10H-Phenothiazinmono
- 10-(2-(1-methyl-2-piperidyl)ethyl)-2-(methylthio)-phenothiazinmonohydrochl
- 10-(2-(1-methyl-2-piperidyl)ethyl)-2-methylthiophenothiazinehydrochloride
- 10-[2-(1-Methyl-2-Piperidyl)-Ethyl]-2-[Methylthiol]-Phenothiazine Hydrochloride
- 10-[2-(1-Methyl-2-Piperidyl)Ethyl]-2-(Methylthio)-10H-Phenothiazine Hydrochloride
- 10-[2-(1-Methyl-2-piperidinyl)ethyl]-2-(methylthio)-10H-phenothiazine Hydrochloride
- 10-[2-(1-Methylpiperidin-2-yl)ethyl]-2-(methylsulfanyl)-10H-phenothiazine hydrochloride
- 10-[2-(1-methylpiperidin-2-yl)ethyl]-2-(methylsulfanyl)-10H-phenothiazine hydrochloride (1:1)
- 10-[3-(1-Methyl-2-piperidyl)ethyl]-2-(methylthio)phenothiazine hydrochloride
- 10H-Phenothiazine, 10-2-(1-methyl-2-piperidinyl)ethyl-2-(methylthio)-, monohydrochloride
- 10H-Phenothiazine, 10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylthio)-, hydrochloride (1:1)
- 10H-Phenothiazine, 10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylthio)-, monohydrochloride (9CI)
- 2-Methylmercapto-10-[2-(N-methyl-2-piperidyl)ethyl]phenothiazine Hydrochloride
- 2-methylmercapto-10-(2-(n-methyl-2-piperidyl)ethyl)phenothiazinehydrochlorid
- Aldazine
- Labotest-Bb Lt00451961
- Mallorol
- Mellaril
- Mellaril hydrochloride
- Melleretten
- Melleril
- NSC 186060
- Novoridazine
- Orsanil
- Phenothiazine, 10-[2-(1-methyl-2-piperidyl)ethyl]-2-(methylthio)-, hydrochloride
- Phenothiazine, 10-[2-(1-methyl-2-piperidyl)ethyl]-2-(methylthio)-, monohydrochloride
- Ridazin
- Stalleril
- THIORIDAZINEHYDROCHLORIDE,USP
- ThioridazinHCl
- Thioridazine Hcl
- Thioridazinhydrochlorid
- Thioril
- Thiozine
- mellarilhydrochloride
- melleril(tablet)
- usafsz-3
- 10-(2-(1-methyl-2-piperidyl)ethyl)-2-(methylthio)-phenothiazinmonohydrochl
- 10-(2-(1-methyl-2-piperidyl)ethyl)-2-methylthiophenothiazinehydrochloride
- 2-methylmercapto-10-(2-(n-methyl-2-piperidyl)ethyl)phenothiazinehydrochlorid
- mellarilhydrochloride
- melleril(tablet)
- usafsz-3
- ThioridazinHCl
- Thioridazinhydrochlorid
- 10-[2-(1-Methyl-2-piperidinyl)ethyl]-2-(methylthio)-10H-phenothiazine Hydrochloride
- 2-Methylmercapto-10-[2-(N-methyl-2-piperidyl)ethyl]phenothiazine Hydrochloride
- Orsanil
- Ridazin
- Stalleril
- 10H-Phenothiazine, 10-2-(1-methyl-2-piperidinyl)ethyl-2-(methylthio)-, monohydrochloride
- THIORIDAZINEHYDROCHLORIDE,USP
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15 produtos.
Thioridazine Hydrochloride
CAS:Fórmula:C21H26N2S2·HClPureza:>98.0%(HPLC)Cor e Forma:White to Almost white powder to crystalPeso molecular:407.03THIORIDAZINE HYDROCHLORIDE CRS
CAS:<p>THIORIDAZINE HYDROCHLORIDE CRS</p>Fórmula:C21H27ClN2S2Cor e Forma:PowderPeso molecular:407.0355Thioridazine Hydrochloride
CAS:<p>Antidepressants, tranquilizers and other pschotherapeutic agents</p>Fórmula:C21H26N2S2·ClHCor e Forma:PowderPeso molecular:406.13042Thioridazine hydrochloride
CAS:<p>Thioridazine hydrochloride (Mellaril) , an antipsychotic drug, is used in the therapy of psychosis and schizophrenia and shows serotonin antagonism or D4</p>Fórmula:C21H27ClN2S2Pureza:99.55% - 99.957%Cor e Forma:White To Off-White SolidPeso molecular:407.04Thioridazine HCl
CAS:Fórmula:C21H26N2S2·HClCor e Forma:White To Off-White SolidPeso molecular:370.58 36.46Thioridazine hydrochloride
CAS:<p>Thioridazine hydrochloride</p>Pureza:≥98%Peso molecular:407.04g/molThioridazine hydrochloride
CAS:Fórmula:C21H26N2S2·HClPureza:≥ 98.0%Cor e Forma:White to off-white powder or crystalsPeso molecular:407.03Thioridazine Hydrochloride
CAS:Produto ControladoFórmula:C21H26N2S2·ClHCor e Forma:NeatPeso molecular:407.04Thioridazine hydrochloride
CAS:Produto ControladoFórmula:C21H26N2S2·ClHCor e Forma:NeatPeso molecular:407.0410-[2-(1-Methylpiperidin-2-yl)ethyl]-2-(methylsulfanyl)-10H-phenothiazine hydrochloride
CAS:<p>10-[2-(1-Methylpiperidin-2-yl)ethyl]-2-(methylsulfanyl)-10H-phenothiazine hydrochloride</p>Fórmula:C21H26N2S2·ClHPureza:98%Cor e Forma: white solidPeso molecular:407.04g/molThioridazine Hydrochloride
CAS:Produto Controlado<p>Applications Thioridazine HCl is a dopamine receptor blocker and antipsychotic. It is the parent compound of sulforidazine and mesoridazine. This compound has been reported to bind strongly to dopamine receptors on cancer stem cells and cause differentiation leaving normal cells alone (see Can. Chem. News 12 July/August 2012).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Goldenthal, E.I., Toxicol. Appl. Pharmacol., 18, 185 (1971), Abdel-Moety, E.M., et al.: Anal. Profile Drug Subs., 18, 459 (1989),<br></p>Fórmula:C21H26N2S2·ClHCor e Forma:Light YellowPeso molecular:407.0410-[2-(1-Methyl-2-piperidinyl)ethyl]-2-(methylthio)-10H-phenothiazine hydrochloride
CAS:Produto Controlado<p>The drug, 10-[2-(1-methyl-2-piperidinyl)ethyl]-2-(methylthio)-10H-phenothiazine hydrochloride (CGP 46660), is a competitive antagonist at the human histamine H3 receptor. It has been shown to bind to the histamine H3 receptor in the range of 0.001 to 1 μM and is selective for this receptor over other receptors. CGP 46660 is an optical sensor that can be used in titration calorimetry experiments to measure changes in heat production when it binds to histamine H3 receptors. The drug also has been shown to inhibit guanine nucleotide-binding protein (G protein) signaling pathways and brain functions such as memory formation, learning, and attention span. These effects were demonstrated in humans by measuring EEG activity. The optimum concentration of CGP 46660 for these effects was found to be between 0.01 and 10 μM.</p>Fórmula:C21H27ClN2S2Pureza:Min. 95%Cor e Forma:PowderPeso molecular:407.04 g/mol
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