CAS 130793-28-1

ácido (2S,3R,5S)-5-(2-formamido-4-metil-pentanóiloxi)-2-hexil-3-hidroxi-hexadecanoico

Descrição:

A substância química com o nome "ácido (2S,3R,5S)-5-(2-formamido-4-metil-pentanóiloxi)-2-hexil-3-hidroxi-hexadecanoico" e número CAS "130793-28-1" é um composto orgânico complexo caracterizado por sua estereoquímica específica e grupos funcionais. Apresenta múltiplos centros quirais, que contribuem para sua estrutura tridimensional única e potencial atividade biológica. A presença de um grupo formamido indica que pode participar de várias interações bioquímicas, enquanto os grupos hexila e ácido hexadecanoico sugerem características hidrofóbicas que podem influenciar sua solubilidade e interações com membranas. O grupo hidroxila aumenta sua polaridade, potencialmente afetando sua reatividade e interações com outras moléculas. Este composto pode ser de interesse na pesquisa farmacêutica ou bioquímica devido à sua complexidade estrutural e potenciais aplicações no desenvolvimento de medicamentos ou como sonda bioquímica. Suas propriedades específicas, como ponto de fusão, solubilidade e reatividade, exigiriam investigação empírica para caracterizar completamente seu comportamento em vários ambientes.

Fórmula: C₂₉H₅₅NO₆

InChI: InChI=1/C29H55NO6/c1-5-7-9-11-12-13-14-15-16-18-24(36-29(35)26(30-22-31)20-23(3)4)21-27(32)25(28(33)34)19-17-10-8-6-2/h22-27,32H,5-21H2,1-4H3,(H,30,31)(H,33,34)/t24-,25-,26?,27+/m0/s1

Chave InChI: InChIKey=FKUNIADJSAJLGB-YIPNQBBMSA-N

SMILES: [C@H](C[C@H]([C@H](CCCCCC)C(O)=O)O)(OC([C@H](CC(C)C)NC=O)=O)CCCCCCCCCCC

Sinónimos:

• L-Leucine, N-formyl-, 1-[3-carboxy-2-hydroxynonyl]dodecyl ester, [2R-[1(S*),2R*,3S*]]-
• L-Leucine, N-formyl-, (1S)-1-[(2R,3S)-3-carboxy-2-hydroxynonyl]dodecyl ester
• N-Formyl-L-leucine (1S)-1-[(2R,3S)-3-carboxy-2-hydroxynonyl]dodecyl ester
• Orlistat Open Ring (2S,3R,5S)-Isomer
• (2S,3R,5S)-Orlistat Open Ring Impurity
• Orlistat Open Ring Epimer impurity (Orlistat Open Ring (2S,3R,5S)-Isomer)
• orlistat open ring epimer impurity
• (Orlistat IMpurity)
• (2S,3S,5S)-5-<<(S)-2-(Formylamino)-4-methylpentanoyl>oxy>-2-hexyl-3-hydroxyhexadecanoic Acid
• Orlistat Related Compound ((2S,3R,5S)-5-[(N-Formyl-L-leucyl)oxy]-2-hexyl-3-hydroxyhexadecanoic acid)
• (2S, 3R, 5S)-5-[(N-ForMyl-L-leucyl)oxy]-2-hexyl-3-hydroxyhexadecanoic acid
• Orlistat Open Ring Impurity (2S,3R,5S)-Isomer
• Orlistat open ring epimer
• (2S,3R,5S)-5-[(N-Formyl-L-leucyl)oxy]-2-hexyl-3-hydroxyhexadecanoic Acid (Orlistat Impurity)
• Orlistat Impurity 26
• N-ForMyl-L-leucine(1S)-1-[(2S,3S)-2-hydroxy-3-[(R)-1-phenylethylcarboMoyl)]
• nonyl]dodecyl-d3 Ester
• Orlistat Impurity
• nonyl]dodecyl Ester

Orlistat Open Ring Epimer ((2S,3R,5S)-5-((formyl-L-leucyl)oxy)-2-hexyl-3-hydroxyhexadecanoic acid)

CAS: 130793-28-1

Acyclic amides (including acyclic carbamates) and their derivatives and salts thereof, nesoi

Fórmula: C₂₉H₅₅NO₆

Cor e Forma: Yellow Solid

Peso molecular: 513.40294

Ref: 45-1A06860

L-Leucine, N-formyl-, (1S)-1-[(2R,3S)-3-carboxy-2-hydroxynonyl]dodecyl ester

CAS: 130793-28-1

Fórmula: C₂₉H₅₅NO₆

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 513.7501

Ref: IN-DA000UYB

Orlistat Impurity 38 (Orlistat Open Ring Epimer)

CAS: 130793-28-1

Fórmula: C₂₉H₅₅NO₆

Cor e Forma: Off-White Solid

Peso molecular: 513.76

Ref: 4Z-O-182

(2S,3R,5S)-5-[(N-Formyl-L-leucyl)oxy]-2-hexyl-3-hydroxyhexadecanoic acid

CAS: 130793-28-1

Fórmula: C₂₉H₅₅NO₆

Pureza: ≥ 90%

Cor e Forma: White, off-white or pale yellow oil or solid

Peso molecular: 513.75

Ref: 7W-GM8818

N-Formyl-L-leucine (1S)-1-[(2R,3S)-3-Carboxy-2-hydroxynonyl]dodecyl Ester

CAS: 130793-28-1

Cor e Forma: Neat

Ref: 86-MM1219.15

(2S,3R,5S)-5-[(N-Formyl-L-leucyl)oxy]-2-hexyl-3-hydroxyhexadecanoic Acid (Orlistat Impurity)

CAS: 130793-28-1

Applications A product from thermal and hydrolytic degradation of Orlistat. Orlistat impurity.
References Stalder, H., et al.: Helv. Chimica Acta, 75, 1593 (1992),

Fórmula: C₂₉H₅₅NO₆

Cor e Forma: Neat

Peso molecular: 513.7501

Ref: TR-F700590

Orlistat Open Ring Epimer impurity

CAS: 130793-28-1

Fórmula: C₂₉H₅₅NO₆

Peso molecular: 513.75

Ref: ST-EA-CP-O11005

(2S,3R,5S)-5-[(N-Formyl-L-leucyl)oxy]-2-hexyl-3-hydroxyhexadecanoic acid

CAS: 130793-28-1

Orlistat is a lipase inhibitor that is used as a weight-loss drug. It works by inhibiting the absorption of dietary fats and their subsequent conversion into triglycerides in the intestines, thereby limiting the calories absorbed. Orlistat has been shown to be effective in lymphatic and fatty acid transport, but oral bioavailability is low due to extensive first-pass metabolism. Orlistat inhibits pancreatic lipase, which may lead to reduced intestinal fat absorption and decreased systemic exposure. This drug also inhibits long-chain fatty acids from being absorbed through the intestinal wall and prevents them from being metabolized, thereby reducing lipid formulations in the blood.

Fórmula: C₂₉H₅₅NO₆

Pureza: Min. 95%

Peso molecular: 513.75 g/mol

Ref: 3D-IF23585