CAS 131-48-6

Ácido acetilneuramínico

Descrição:

Ácido acetilneuramínico, comumente referido como ácido siálico, é um açúcar amino que ocorre naturalmente e é um derivado do ácido neuramínico. É caracterizado por seu papel como um componente crucial de glicoproteínas e glicolípidos, particularmente nas membranas celulares dos animais. Este composto é conhecido por sua carga negativa em pH fisiológico, o que contribui às suas funções biológicas, incluindo reconhecimento celular, sinalização e modulação da resposta imune. Ácido acetilneuramínico é tipicamente encontrado em altas concentrações em tecidos como o cérebro e está envolvido em vários processos biológicos, incluindo reconhecimento de patógenos e modulação de interações celulares. Sua estrutura apresenta uma espinha dorsal de nove carbonos com um grupo acetila, o que melhora sua solubilidade e estabilidade. A presença de grupos hidroxila e amino permite uma extensa formação de ligações de hidrogênio, influenciando suas interações com outras biomoléculas. Devido à sua importância na comunicação celular e suas potenciais implicações na saúde e na doença, Ácido acetilneuramínico é um assunto de interesse em bioquímica e pesquisa médica.

Fórmula: C₁₁H₁₉NO₉

InChI: InChI=1S/C11H19NO9/c1-4(14)12-8(5(15)2-6(16)11(20)21)10(19)9(18)7(17)3-13/h5,7-10,13,15,17-19H,2-3H2,1H3,(H,12,14)(H,20,21)/t5-,7+,8+,9+,10+/m0/s1

Chave InChI: InChIKey=KBGAYAKRZNYFFG-BOHATCBPSA-N

SMILES: [C@H]([C@H]([C@@H]([C@@H](CO)O)O)O)([C@H](CC(C(O)=O)=O)O)NC(C)=O

Sinónimos:

• 5-N-Acetyl-<span class="text-smallcaps">D</span>-neuraminic acid
• 5-N-Acetyl-D-neuraminic acid
• 5-N-Acetylneuraminic acid
• <span class="text-smallcaps">D</smallcap>-glycero-<smallcap>D</span>-galacto-2-Nonulosonic acid, 5-(acetylamino)-3,5-dideoxy-
• <span class="text-smallcaps">D</smallcap>-glycero-<smallcap>D</span>-galacto-Nonulosonic acid, 5-acetamido-3,5-dideoxy-
• Aceneuramic acid
• Acetylneuraminic acid
• Acide N-acetylneuraminique
• D-glycero-D-galacto-2-Nonulosonic acid, 5-(acetylamino)-3,5-dideoxy-
• D-glycero-D-galacto-Nonulosonic acid, 5-acetamido-3,5-dideoxy-
• Lactaminic acid
• N-Acetyl-<span class="text-smallcaps">D</span>-neuraminic acid
• N-Acetyl-D-neuraminic acid
• N-Acetylneuramic acid
• N-Acetylneuraminsaure
• N-Acetylsialic acid
• N-acetylneuraminic acid
• Nana
• Ux 001
• acido N-acetilneuraminico
• 5-(acetylamino)-3,5-dideoxy-D-glycero-beta-D-galacto-non-2-ulopyranosonic acid
• 5-Acetamido-3,5-dideoxy-D-glycero-D-galactonulosonic acid
• (6xi)-5-(acetylamino)-3,5-dideoxy-beta-D-gluco-non-2-ulopyranosonic acid
• Galactononulosonic acid
• o-Sialic acid
• SialicAcid/N-acetylneuraminicacids
• Sialic Acid
• 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-2-ulopyranosonic acid
• 5-(acetylamino)-3,5-dideoxy-D-glycero-alpha-D-galacto-non-2-ulopyranosonic acid

N-Acetylneuraminic Acid

CAS: 131-48-6

Fórmula: C₁₁H₁₉NO₉

Pureza: >98.0%(T)(HPLC)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 309.27

Ref: 3B-A1105

N-Acetylneuraminic Acid

CAS: 131-48-6, 2109762-46-9

Fórmula: C₁₁H₁₉NO₉

Pureza: >98.0%(T)(HPLC)

Cor e Forma: White to Light yellow powder to crystal

Peso molecular: 309.27

Ref: 3B-A0639

N-(-)-Acetylneuraminic acid, 97%

CAS: 131-48-6

N-Acetylneuraminic acid is useful biologically in neurotransmission, leukocyte extravasation, viral or bacterial infections and carbohydrate-protein recognition. Neu5Ac is used to study its biochemistry, metabolism and uptake. Neu5Ac is used in the development of nanocarriers. This Thermo Scientific

Fórmula: C₁₁H₁₉NO₉

Pureza: 97%

Cor e Forma: White, Powder or crystals or crystalline powder

Peso molecular: 309.27

Ref: 02-L13950

N-Acetylneuraminic acid

CAS: 131-48-6

N-Acetylneuraminic acid (Acide aceneuramique) is a nine-carbon sialic acid monosaccharide commonly found in glycoproteins on cell membranes and in glycolipids

Fórmula: C₁₁H₁₉NO₉

Pureza: 98.88% - 99.97%

Cor e Forma: Solid

Peso molecular: 309.27

Ref: TM-T1638

N-Acetylneuraminic acid

CAS: 131-48-6

N-Acetylneuraminic acid

Pureza: ≥98%

Peso molecular: 309.27g/mol

Ref: 54-BUP16765

N-Acetylneuraminic acid

CAS: 131-48-6

N-Acetylneuraminic acid

Fórmula: C₁₁H₁₉NO₉

Pureza: 97%

Cor e Forma: white solid

Peso molecular: 309.27g/mol

Ref: 54-OR8154

N-Acetyl-Neuraminic acid (Sialic acid)

CAS: 131-48-6

Fórmula: C11H19NO9

Pureza: >98%

Cor e Forma: Solid

Peso molecular: 309.27

Ref: 48-56-1150

N-acetylneuraminic acid

CAS: 131-48-6

Fórmula: C₁₁H₁₉NO₉

Pureza: 95%~99%

Peso molecular: 309.271

Ref: BP-BP4175

N-Acetylneuraminic acid

CAS: 131-48-6

Fórmula: C₁₁H₁₉NO₉

Pureza: ≥ 98.0% (anhydrous)

Cor e Forma: White to off-white powder

Peso molecular: 309.28

Ref: 7W-GC7214

N-Acetylneuraminic Acid

CAS: 131-48-6

Fórmula: C₁₁H₁₉NO₉

Peso molecular: 309.27

Ref: 4Z-S-119002

N-Acetylneuraminic acid

CAS: 131-48-6

N-Acetylneuraminic acid

Fórmula: C₁₁H₁₉NO₉

Pureza: 98%

Cor e Forma: white powder

Peso molecular: 309.27g/mol

Ref: 54-BIM1062

N-Acetylneuraminic Acid

Produto Controlado

CAS: 131-48-6

Applications N-Acetyl-β-neuraminic Acid is a useful reagent in sequential esterification and acetylation of β-​Sialyl phosphite and phosphoramidite.
References Methods Enzymol., 5, 391 (1962), Biochemistry, 18, 2086 (1979)

Fórmula: C₁₁H₁₉NO₉

Cor e Forma: Off White

Peso molecular: 309.27

Ref: TR-A187000

N-Acetyl-D-[1,2,3-13C3]neuraminic Acid

CAS: 131-48-6

Applications Carbon 13 labelled analogue of N-Acetylneuraminic acid (A187000).
References Methods Enzymol., 5, 391 (1962), Biochemistry, 18, 2086 (1979)

Fórmula: C₈₁₃C₃H₁₉NO₉

Cor e Forma: Off-White

Peso molecular: 312.25

Ref: TR-A187007

N-Acetylneuraminic Acid-13C,d3

Produto Controlado

CAS: 131-48-6

Stability Hygroscopic
Applications N-Acetylneuraminic Acid-13C,d3 is a labelled Neuraminic Acid derivative.
References Oetke, C., et al.: J. Biol. Chem., 277, 6688 (2002)

Fórmula: C₁₀₁₃CH₁₆D₃NO₉

Cor e Forma: Neat

Peso molecular: 313.28

Ref: TR-A187009

N-Acetylneuraminic acid

CAS: 131-48-6

N-Acetylneuraminic acid (NANA or Neu5Ac), as the most common sialic acid, is a nine-carbon monosaccharide whose amino group is acetylated (Collins, 2006). Sialic acid is found across the animal kingdom and some prokaryotes. Sialic acid occurs as a component of oligosaccharides (N- and O-linked glycoproteins, glycolipids, human milk, blood groups), bacterial polysaccharides and glycoconjugates. Sialic acid is also found in free form in body fluids (Schauer, 1997).

Fórmula: C₁₁H₁₉NO₉

Pureza: Min. 98 Area-%

Cor e Forma: White Powder

Peso molecular: 309.27 g/mol

Ref: 3D-MA00746

N-Acetyl-D-[1,2,3-¹³C3]neuraminic acid

CAS: 131-48-6

N-Acetyl-D-[1,2,3-¹³C3]neuraminic acid is a modification of the natural sugar N-acetylneuraminic acid. It can be synthesized by reacting 1,2,3-¹³C3]cytidine with sodium hydroxide and acetic anhydride in methanol. It is a carbohydrate that can be found in many plants and animals. This compound has been shown to inhibit glycosylation and methylation reactions. N-Acetyl-D-[1,2,3-¹³C3]neuraminic acid is also a monosaccharide that belongs to the group of sugars. Due to its high purity and availability, this substance can be used as a substitute for sialic acid in research experiments.

Fórmula: C₃C₈H₁₉NO₉

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 312.25 g/mol

Ref: 3D-MA182016

N-Acetylneuraminic Acid extrapure (NANA), 98%

CAS: 131-48-6

Fórmula: C₁₁H₁₉NO₉

Pureza: min. 99%

Cor e Forma: White, Powder

Peso molecular: 309.28

Ref: SR-86419

N-Acetylneuraminic acid

CAS: 131-48-6

Fórmula: C₁₁H₁₉NO₉

Pureza: 97.0%

Cor e Forma: Solid, White powder

Peso molecular: 309.271

Ref: 10-F047790

N-Acetyl-D-[2,3-13C2]neuraminic Acid

Produto Controlado

CAS: 131-48-6

Applications Carbon 13 labelled analogue of N-Acetylneuraminic acid (A187000).
References Methods Enzymol., 5, 391 (1962), Biochemistry, 18, 2086 (1979)

Fórmula: C₂C₉H₁₇NO₉

Cor e Forma: Neat

Peso molecular: 309.239

Ref: TR-A187006

N-Acetyl-D-Neuraminic Acid-13C

Produto Controlado

CAS: 131-48-6

Applications Carbon 13 labelled analogue of N-Acetylneuraminic acid (A187000).
References Methods Enzymol., 5, 391 (1962), Biochemistry, 18, 2086 (1979)

Fórmula: C₁₀₁₃CH₁₉NO₉

Cor e Forma: Off-White

Peso molecular: 310.27

Ref: TR-A187003