CAS 132866-11-6
:Cloridrato de lercanidipino
Descrição:
Cloridrato de lercanidipino é um bloqueador de canais de cálcio utilizado principalmente no tratamento da hipertensão. Pertence à classe de antagonistas do cálcio dihidropiridínicos, que atuam inibindo a entrada de íons de cálcio no músculo liso vascular e no músculo cardíaco, levando à vasodilatação e à redução da pressão arterial. A substância é caracterizada por sua alta lipofilicidade, o que melhora sua absorção e biodisponibilidade. A lercanidipina apresenta uma longa meia-vida, permitindo a dosagem uma vez ao dia, o que melhora a adesão do paciente. É tipicamente administrada em sua forma de sal hidroclorídico, o que melhora sua solubilidade em soluções aquosas. O composto é conhecido por sua seletividade pelos vasos sanguíneos periféricos, minimizando os efeitos sobre a contratilidade cardíaca e a frequência cardíaca. Efeitos colaterais comuns podem incluir edema periférico, dor de cabeça e rubor. Assim como outros bloqueadores de canais de cálcio, recomenda-se cautela em pacientes com certas condições cardiovasculares. No geral, Cloridrato de lercanidipino é um agente antihipertensivo eficaz com um perfil farmacocinético favorável.
Fórmula:C36H42ClN3O6
InChI:InChI=1/C36H41N3O6.ClH/c1-24-31(34(40)44-6)33(28-18-13-19-29(22-28)39(42)43)32(25(2)37-24)35(41)45-36(3,4)23-38(5)21-20-30(26-14-9-7-10-15-26)27-16-11-8-12-17-27;/h7-19,22,30,33,37H,20-21,23H2,1-6H3;1H
Chave InChI:InChIKey=WMFYOYKPJLRMJI-UHFFFAOYSA-N
SMILES:C(OC(CN(CCC(C1=CC=CC=C1)C2=CC=CC=C2)C)(C)C)(=O)C=3C(C(C(OC)=O)=C(C)NC3C)C4=CC(N(=O)=O)=CC=C4.Cl
Sinónimos:- 1,4-Dihydro-2,6-Dimethyl-4-(3-Nitrophenyl)-3,5-Pyridinedicarboxylic Acid 2-[(3,3-Diphenylpropyl)Methylamino]-1,1-Dimethylethyl Methyl Ester Hydrochloride
- 1,4-Dihydro-2,6-dimethyl-4-(3-nittrophenyl)-3,5-pyridinedicarboxylic Acid 2-[(3,3-Diphenylpropyl)methylamino]-1,1-dimethylethyl Methyl Ester Hydrochloride
- 1,4-Dihydro-2,6-dimethyl-4-(3-nittrophenyl)-3,5-pyridinedicarboxylicAcid2-[(3,3-Diphenylpropyl)methylamino]-1,1-dimeth
- 1-[(3,3-Diphenylpropyl)(Methyl)Amino]-2-Methylpropan-2-Yl Methyl 2,6-Dimethyl-4-(3-Nitrophenyl)-1,4-Dihydropyridine-3,5-Dicarboxylate Hydrochloride (1:1)
- 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl methyl ester, monohydrochloride
- 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-[2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl] 5-methyl ester, hydrochloride (1:1)
- Cardiovasc
- Carmen
- Corifeo
- Lercadip
- Lercan
- Lercanidipine Hcl
- LercanidipineHcl
- Lercanidipinehydrochloride(Forr&Donly)
- Lercapin
- Lercaridipin HCL
- Lercaton
- Lerkamen
- Lervasc
- Lerzam
- Lotensyl
- Rec 15/2375
- Renovia
- Vasodip
- Zandip
- Zanicor
- Lercanidipine hydrochloride
- BCL-10 human
- B-cell lymphoma/leukemia 10
- 1,4-dihydro-2,6-diMethyl-4-(3-nitrophenyl)-3,5-
- 3,5-Pyridinedicarboxylicacid, 1,4-dihydro-2,6-diMethyl-4-(3-nitrophenyl)-,3-[2-[(3,3-diphenylpropyl)MethylaMino]-1,1-diMethylethyl] 5-Methyl ester,hydrochloride (1:1)
- Lercaridipine
- Lercanidipine hemihydrate hydrochloride
- B-cell CLL/lymphoma 10
- CLAP
- 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl methyl ester 3,5-pyridinedicarboxylic acid hydrochloride
- CIPER
- 75
- O3-[1-[3,3-diphenylpropyl(methyl)amino]-2-methyl-propan-2-yl] O5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride
- 3-O-[1-[3,3-diphenylpropyl(methyl)amino]-2-methylpropan-2-yl] 5-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride
- c-E10
- CARD-containing molecule enhancing NF-κ-B
- Lercanidipine hydrochloride heMihydrate
- 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid O3-[2-[3,3-diphenylpropyl(methyl)amino]-1,1-dimethyl-ethyl] ester O5-methyl ester hydrochloride
- mE10
- Ver mais sinónimos
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100
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16 produtos.
Lercanidipine Hydrochloride
CAS:Fórmula:C36H41N3O6·HClPureza:>98.0%(T)(HPLC)Cor e Forma:Light orange to Yellow to Green powder to crystalPeso molecular:648.20Lercanidipine Hydrochloride (2-[(3,3-Diphenylpropyl)methylamino]-1,1-dimethylethyl methyl (4RS)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate monohydrochloride)
CAS:Compounds containing an unfused pyridine ring in the structure, nesoiFórmula:C36H41N3O6·HClPeso molecular:611.299543,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-[2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl] 5-methyl ester, hydrochloride (1:1)
CAS:Fórmula:C36H42ClN3O6Pureza:98%Cor e Forma:SolidPeso molecular:648.1882Lercanidipine-13C-d3 HCl
CAS:Fórmula:C3513CH38D3N3O6·HClCor e Forma:Yellow SolidPeso molecular:615.75 36.46Lercanidipine hydrochloride
CAS:Fórmula:C36H41N3O6·HCl·xH2OPureza:(HPLC) ≥ 98.0%Cor e Forma:Light-yellow to yellow powder or crystalsPeso molecular:648.19 (anhydrous)Lercanidipine hydrochloride
CAS:Lercanidipine hydrochloride (Corifeo) is a calcium channel blocker of the dihydropyridine class.Fórmula:C36H41N3O6·HClPureza:99.86% - 99.91%Cor e Forma:Pale-Yellow PowderPeso molecular:648.19Lercanidipine Hydrochloride
CAS:Produto ControladoFórmula:C36H41N3O6·ClHCor e Forma:Light YellowPeso molecular:648.19Lercanidipine HCl - Bio-X ™
CAS:<p>Lercanidipine is a calcium channel blocker that is used for the treatment of hypertension. This drug inhibits ion channels and interferes with the release of calcium from the sarcoplasmic reticulum. As a result, coronary and systemic arteries are dilated, allowing for an increased supply of oxygen to myocardial tissue. .</p>Fórmula:C36H41N3O6•HClPureza:Min. 95%Cor e Forma:PowderPeso molecular:648.19 g/molLercanidipine hydrochloride
CAS:<p>Calcium channel blocker</p>Fórmula:C36H42ClN3O6Pureza:Min. 95%Cor e Forma:PowderPeso molecular:648.19 g/mol3-(1-((3,3-Diphenylpropyl)(methyl)amino)-2-methylpropan-2-yl) 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride
CAS:Pureza:98%Peso molecular:648.2000122
