CAS 1335202-59-9

Febuxostat Related Compound D (2-[4-(sec-Butoxy)-3-cyanophenyl]-4-methylthiazole-5-carboxylic acid)

CAS: 1335202-59-9

Compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure

Fórmula: C₁₆H₁₆N₂O₃S

Cor e Forma: Off-White Fine Powder

Peso molecular: 316.08816

Ref: 45-1269384

Febuxostat sec-butoxy acid

CAS: 1335202-59-9

Febuxostat sec-butoxy acid

Pureza: 95%

Ref: 54-OR1038213

Febuxostat sec-butoxy acid

CAS: 1335202-59-9

Febuxostat sec-butoxy acid is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a K i of 0.6 nM [1] .

Fórmula: C₁₆H₁₆N₂O₃S

Cor e Forma: Solid

Peso molecular: 316.37

Ref: TM-T73966

Febuxostat USP Related Compound D

CAS: 1335202-59-9

Fórmula: C₁₆H₁₆N₂O₃S

Cor e Forma: Pale Grey Solid

Peso molecular: 316.38

Ref: 4Z-F-3936

Febuxostat 2-Butyl Isomer

Produto Controlado

CAS: 1335202-59-9

Applications Febuxostat 2-butyl Isomer is an impurity of Febuxostat (F229000) which is a xanthine oxidase/xanthine dehydrogenase inhibitor.
References Osada, Y., et al.: Eur. J. Pharmacol., 241, 183 (1993); Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003); Mayer, M.D., et al.: Am. J. Therap., 12, 22 (2005); Tomlinson, B., et al.: Curr. Opin. Invest. Drugs, 6, 1168 (2005)

Fórmula: C₁₆H₁₆N₂O₃S

Cor e Forma: Neat

Peso molecular: 316.37

Ref: TR-F229040

Febuxostat sec-Butyl Ether Acid Impurity

CAS: 1335202-59-9

Fórmula: C₁₆H₁₆N₂O₃S

Peso molecular: 316.38

Ref: ST-EA-CP-F7004

2-(4-(SEC-BUTOXY)-3-CYANOPHENYL)-4-METHYLTHIAZOLE-5-CARBOXYLIC ACID

CAS: 1335202-59-9

Pureza: 95%

Peso molecular: 316.3800049

Ref: 10-F796281

Febuxostat Sec-butoxy acid

CAS: 1335202-59-9

Febuxostat is a non-peptide inhibitor of xanthine oxidase (XO), an enzyme that catalyzes the conversion of xanthine and hypoxanthine to uric acid. Febuxostat is used as a treatment for chronic gout in adults who are not adequately controlled on allopurinol alone or who cannot tolerate allopurinol. Febuxostat has been shown to be effective in inhibiting the activity of human recombinant XO, both in vitro and in vivo. The compound is a competitive inhibitor of L-histidine with an IC50 of 0.3 microM at pH 7.4 and 0.1 microM at pH 6.0, which is more potent than other peptidomimetics such as febuprofen and fexofenadine, but less potent than CGP57148B and CGP37849A.
Febuxostat has also been shown to have

Fórmula: C₁₆H₁₆N₂O₃S

Pureza: Min. 95%

Peso molecular: 316.4 g/mol

Ref: 3D-KDC20259