CAS 133845-63-3

PF-9601N

CAS: 133845-63-3

PF-9601N

Pureza: ≥98%

Peso molecular: 290.36g/mol

Ref: 54-BUP10824

PF-9601N

CAS: 133845-63-3

PF-9601N: potent, selective MAO-BI with neuroprotection in PD models.

Fórmula: C₁₉H₁₈N₂O

Pureza: 98.29%

Cor e Forma: Solid

Peso molecular: 290.36

Ref: TM-T8849

PF9601N

CAS: 133845-63-3

PF9601N is a selective inhibitor of the enzyme dopamine-beta-hydroxylase (DBH). DBH is a rate-limiting enzyme in the synthesis of dopamine, and PF9601N has been shown to provide neuroprotection against neuronal death. PF9601N binds reversibly to the active site of DBH and inhibits amine oxidation, thereby inhibiting the production of norepinephrine and epinephrine. The basic structure of PF9601N is similar to that of reserpine, which was used for decades as an antihypertensive drug. The in vivo model for PF9601N is rat striatal cells treated with 6-hydroxydopamine, which induces cell death by apoptosis. In response to this treatment, cells treated with PF9601N showed significantly less neuronal death than those not treated with the compound.

Fórmula: C₁₉H₁₈N₂O

Pureza: Min. 95%

Peso molecular: 290.36 g/mol

Ref: 3D-IFA84563