CAS 134-63-4
:Cloridrato de (-)-Lobelina
Descrição:
Cloridrato de (-)-Lobelina é um composto químico que é conhecido principalmente por seu uso em farmacologia e como um potencial agente terapêutico. É um alcaloide derivado da planta Lobelia inflata, comumente conhecida como tabaco indiano. Este composto exibe uma variedade de atividades biológicas, incluindo efeitos no sistema nervoso central, onde pode atuar como um estimulante ou um depressor, dependendo da dosagem e do contexto. Cloridrato de (-)-Lobelina é caracterizado por sua natureza quiral, com o "(-)" indicando sua estereoisomeria específica, que é crucial para sua atividade biológica. A forma de sal hidroclorídrico melhora sua solubilidade em água, tornando-o mais adequado para aplicações farmacêuticas. Além de seus potenciais usos terapêuticos, (-)-Lobelina tem sido estudada por seus efeitos sobre a dependência de nicotina e como um estimulante respiratório. No entanto, seu uso está sujeito a escrutínio regulatório devido a preocupações com segurança e eficácia. No geral, Cloridrato de (-)-Lobelina é um composto de interesse tanto em química medicinal quanto em farmacologia, com pesquisas em andamento sobre suas várias aplicações.
Fórmula:C22H27NO2·ClH
InChI:InChI=1S/C22H27NO2.ClH/c1-23-19(15-21(24)17-9-4-2-5-10-17)13-8-14-20(23)16-22(25)18-11-6-3-7-12-18;/h2-7,9-12,19-21,24H,8,13-16H2,1H3;1H/t19-,20+,21-;/m0./s1
Chave InChI:InChIKey=MKMYPTLXLWOUSO-NFQNBQCWSA-N
SMILES:C([C@H](O)C1=CC=CC=C1)[C@H]2N(C)[C@@H](CC(=O)C3=CC=CC=C3)CCC2.Cl
Sinónimos:- (-)-α-Lobeline hydrochloride
- 2-((2R,6S)-6-((S)-2-Hydroxy-2-Phenylethyl)-1-Methylpiperidin-2-Yl)-1-Phenylethanone Hydrochloride
- 2-(6-(2-Hydroxy-2-Phenethyl)-1-Methyl-2-Piperidyl)Acetophenone Hydrochloride
- 2-[6-(2-Hydroxy-2-Phenylethyl)-1-Methylpiperidin-2-Yl]-1-Phenylethanone Hydrochloride (1:1)
- 2-{(2R,6S)-6-[(2R)-2-hydroxy-2-phenylethyl]-1-methylpiperidin-2-yl}-1-phenylethanone hydrochloride
- 2-{(2R,6S)-6-[(2S)-2-hydroxy-2-phenylethyl]-1-methylpiperidin-2-yl}-1-phenylethanone
- 2-{(2R,6S)-6-[(2S)-2-hydroxy-2-phenylethyl]-1-methylpiperidin-2-yl}-1-phenylethanone hydrochloride (1:1)
- Butane-1,4-Diyl Dimethanesulfonate
- Ethanone, 2-[(2R,6S)-6-[(2S)-2-hydroxy-2-phenylethyl]-1-methyl-2-piperidinyl]-1-phenyl-, hydrochloride
- Ethanone, 2-[(2R,6S)-6-[(2S)-2-hydroxy-2-phenylethyl]-1-methyl-2-piperidinyl]-1-phenyl-, hydrochloride (1:1)
- Ethanone, 2-[6-(2-hydroxy-2-phenylethyl)-1-methyl-2-piperidinyl]-1-phenyl-, hydrochloride, [2R-[2α,6α(S*)]]-
- Lobelin hydrochloride
- Lobeline HCL
- Lobron
- Vuf 10751
- Zoolobelin
- alpha-Lobeline hydrochloride
- (-)-Lobeline hydrochloride
- Lobeline hydrochloride
- Lobeline, hydrochloride
- ALPHA-LOBELIN HCL
- 2-(6-(beta-hydroxyphenethyl)-1-methyl-2-piperidyl)-acetophenonhydrochlor
- A-LOBELINE HCL
- 2-(6-[2-HYDROXY-2-PHENYLETHYL]-1-METHYL-2-PIPERIDINYL)-1-PHENYLETHANONE HYDROCHLORIDE
- 2-(6-[2-Hydroxy-2-phenylethyl]-1-methyl-2-piperidinyl)-1-phenylethanone, L-Lobeline, Hydrochloride
- LOBELINE HCL, A-
- 2-[6-(.beta.-hydroxyphenethyl)-1-methyl-2-piperidyl]-,hydrochloride,(-)-Acetophenone
- 2-[(2r,6s)-6-[(2s)-2-hydroxy-2-phenyl-ethyl]-1-methyl-2-piperidyl]-1-phenyl-ethanone hydrochloride
- 2-[6-(2-HYDROXY-2-PHENETHYL)-1-METHYL-2-PIPERIDYL]ACETOPHENONE HCL
- Apolipoprotein B (LDL), Sheep anti-Human, Guinea pig, Swine (NO X w/Bovine, Horse, Dog, Cat, Rabbit, Chicken, Goat, Mouse, Rat)
- Lobelinhydrochloride
- L-LOBELINE HYDROCHLORIDE
- [2-[(2R,6S)-6-[(2S)-2-HYDROXYPHENETHYL]]-1-METHYL-2-PIPERIDYL]ACETOPHENONE HYDROCHLORIDE
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11 produtos.
Lobeline hydrochloride
CAS:Lobeline hydrochloride (α-Lobeline hydrochloride) is a nicotinic receptor agonist, acting as an effective antagonist at both α4β2 and α3β2 neuronal nicotinicFórmula:C22H27NO2·HClPureza:99.31% - 99.43%Cor e Forma:Rosettes Of Slender Needles From Alc White To Off-White SolidPeso molecular:373.92Lobeline HCl
CAS:Fórmula:C22H27NO2·HClCor e Forma:White To Off-White SolidPeso molecular:337.46 36.46(-)-Lobeline hydrochloride
CAS:Fórmula:C22H27NO2·HClPureza:≥ 97.0%Cor e Forma:White to off-white powderPeso molecular:373.92Lobeline Hydrochloride
CAS:Produto ControladoFórmula:C22H27NO2·ClHCor e Forma:NeatPeso molecular:373.92a-Lobeline hydrochloride
CAS:<p>a-Lobeline hydrochloride is an alkaloid-based compound, which is primarily derived from the Lobelia plant species. It functions as a nicotinic acetylcholine receptor antagonist and dopamine transporter inhibitor, interacting with the central nervous system to modulate neurotransmitter activities. This compound has historically been explored for its potential in nicotine addiction treatment due to its ability to inhibit the reuptake of dopamine, thereby influencing reward pathways associated with addiction.</p>Fórmula:C22H28ClNO2Pureza:Min. 95%Cor e Forma:White/Off-White SolidPeso molecular:373.92 g/mol2-(6-(2-Hydroxy-2-phenylethyl)-1-methylpiperidin-2-yl)-1-phenylethanone hydrochloride
CAS:Fórmula:C22H28ClNO2Pureza:98%Peso molecular:373.92α-Lobeline Hydrochcloride
CAS:Produto Controlado<p>Applications A neuronal nicotinic acetylcholine receptor agonist. A CNS stimulant.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Damaj, M.I., et al.: J. Pharmacol. Exp. Ther., 282, 410 (1997), Toth, P.T., et al.: Eur. J. Pharmacol., 363, 75 (1998), Flammia, D., et al.: J. Med. Chem., 42, 3726 (1999), Dwoskin, P.A., et al.: Biochem. Pharmacol., 63, 89 (2002),<br></p>Fórmula:C22H27NO2·ClHCor e Forma:NeatPeso molecular:373.92
