CAS 13422-51-0
:Cobinamida, Co-hidroxi-, f-(dihidrogênio fosfato), sal interna, 3'-éster com (5,6-dimetil-1-α-D-ribofuranosil-1H-benzimidazol-κN3)
Descrição:
Cobinamida, Co-hidroxi-, f-(dihidrogênio fosfato), sal interna, 3'-éster com (5,6-dimetil-1-α-D-ribofuranosil-1H-benzimidazol-κN3) é um composto químico complexo que apresenta uma estrutura contendo cobalto, que é significativa em sistemas biológicos, particularmente no metabolismo da vitamina B12. Este composto é caracterizado pela sua coordenação com cobalto, que desempenha um papel crucial em várias reações enzimáticas. A presença de um grupo fosfato sugere uma potencial solubilidade em ambientes aquosos, aumentando sua biodisponibilidade. O moiety 5,6-dimetil-1-α-D-ribofuranosilo-1H-benzimidazol indica uma semelhança estrutural com nucleosídeos, o que pode influenciar sua interação com macromoléculas biológicas. Como uma sal interna, provavelmente exibe propriedades iônicas únicas que podem afetar sua estabilidade e reatividade. No geral, a intrincada estrutura e os grupos funcionais deste composto sugerem aplicações potenciais em bioquímica e farmacologia, particularmente em estudos relacionados a derivados da vitamina B12 e seus papéis fisiológicos. Mais pesquisas seriam necessárias para elucidar suas atividades biológicas específicas e possíveis usos terapêuticos.
Fórmula:C62H90ClCoN13O15P
InChI:InChI=1S/C62H90N13O14P.Co.H2O/c1-29-20-40-41(21-30(29)2)75(28-70-40)56-52(84)53(42(27-76)87-56)89-90(85,86)88-31(3)26-69-49(83)19-15-36-50-32(4)54-58(6,7)34(12-16-43(63)77)38(71-54)22-39-35(13-17-44(64)78)59(8,23-46(66)80)55(72-39)33(5)51-37(14-18-45(65)79)61(10,25-48(68)82)62(11,74-51)57(73-50)60(36,9)24-47(67)81;;/h20-22,28,31,34-37,42,52-53,56-57,76,84H,12-19,23-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);;1H2/q;+3;/p-3
Chave InChI:InChIKey=YOZNUFWCRFCGIH-UHFFFAOYSA-K
SMILES:[OH-][Co+3]1234[N]=5C6(C)C7[N-]1C(C(C)(C7CC(N)=O)CCC(=O)NCC(C)OP(=O)([O-])OC8C(O)C(N9C=[N]2C=%10C9=CC(C)=C(C)C%10)OC8CO)=C(C)C%11=[N]3C(=CC%12=[N]4C(=C(C)C5C(CCC(N)=O)C6(CC(N)=O)C)C(CC(N)=O)(C)C%12CCC(N)=O)C(C)(C)C%11CCC(N)=O
Sinónimos:- Alpha Cobione
- AlphaRedisol
- Axlon
- Ciplamin H
- Cobalamin, hydroxo-
- Cobalex
- Cobalin H
- Cobinamide hydroxide phosphate 3'-ester with 5,6-dimethyl-1-α-D-ribofuranosylbenzimidazole inner salt
- Cobinamide hydroxide phosphate 3′-ester with 5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosylbenzimidazole inner salt
- Cobinamide, Co-hydroxy-, f-(dihydrogen phosphate), inner salt, 3′-ester with (5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosyl-1H-benzimidazole-κN<sup>3</sup>)
- Cobinamide, dihydroxide, dihydrogen phosphate (ester), mono (inner salt), 3'-ester with 5,6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole
- Cobinamide, dihydroxide, dihydrogen phosphate (ester), mono(inner salt), 3'-ester with 5,6-dimethyl-1-α-D-ribofuranosylbenzimidazole
- Cobinamide, dihydroxide, dihydrogen phosphate (ester), mono(inner salt), 3′-ester with 5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosyl-1H-benzimidazole
- Cobinamide, dihydroxide, dihydrogen phosphate (ester), mono(inner salt), 3′-ester with 5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosylbenzimidazole
- Codroxomin
- Cyanokit
- Depovit B12
- Docclan
- Docelan
- Docevita
- Droxomin
- Ducobee Hy
- Duradoce
- Duralta-12
- Hidroxocobalamina
- Hydrocobalamin
- Hydrogrisevit
- Hydrovit
- Hydroxocobalamin
- Hydroxocobalamine
- Hydroxocobemine
- Hydroxy vitamin B12
- Hydroxy vitamin B<sub>12</sub>
- Hydroxycobalamin
- Hydroxycobalamine
- Hyxobamine
- Idrogrisevit
- Megamilbedoce
- Neo-Betalin 12
- Neo-Cytamen
- Neo-Macrabin
- Neo-Rojamin
- OH-Duphar
- Oxobemin
- Primabalt RP
- Redisol H
- Sytobex H
- Vibeden
- Vitadurin
- Vitamin B12a
- Vitamin B<sub>12a</sub>
- α-(5,6-Dimethylbenzimidazolyl)hydroxocobamide
- Cobinamide,Co-hydroxy-, f-(dihydrogen phosphate), inner salt, 3'-ester with(5,6-dimethyl-1-a-D-ribofuranosyl-1H-benzimidazole-kN3)
- Hydroxocobalamin Vitamin B12
- hydroxy-[(1R,2R,3R,4Z,7S,9Z,12S,13S,14Z,17S,18S,19R)-2,13,18-tris(2-amino-2-oxo-ethyl)-7,12,17-tris(3-amino-3-oxo-propyl)-3-[3-[[(2R)-2-[[(2R,3S,4R,5S)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-yl]oxy-oxido-phosphoryl]oxypropyl]amino]-3-oxo-propyl]-3,5,8,8,13,15,18,19-octamethyl-2,7,12,17-tetrahydro-1H-corrin-21-yl]cobalt(1+) hydrochloride
- Cobinamide, Co-hydroxy-, f-(dihydrogen phosphate), inner salt, 3′-ester with (5,6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole-κN3)
- Cobinamide,dihydroxide, dihydrogen phosphate (ester), mono(inner salt), 3'-ester with5,6-dimethyl-1-a-D-ribofuranosyl-1H-benzimidazole
- alphacobione
- HYDROXOCOBALAMINE HYDROCHLORIDE
- Hydroxocobalamin CRS
- Hydroxocobalamin Acetate/Hydroxocobalamin HCL (Vitamin B12)
- hydroxycobalamin (both acetate and HCl)
- Coalpha-[alpha-(5,6-dimethylbenzimidazolyl)]-Cobeta-hydroxocobamide
- cobinamide,dihydroxide,dihydrogenphosphate(ester),mono(innersalt),3’-est
- vitaminb(sub12a)
- sterwith5,6-dimethyl-1-alpha-d-ribofuranosylbenzimidazole
- erwith5,6-dimethyl-1-alpha-d-ribofuranosyl-1h-benzimidazole
- HYDOXOCOBALAMIN
- Hydroxocobalamin/Hydrovit/vitamin B12 CAS NO.13422-51-0
- axion
- hydroxo-cobalami
- HYDROXYCOBALAMIN HYDROCHLORIDE
- High purity Hydroxocobalamin
- lyovit-h
- OH-CBL HCL
- ohb12
- cobinamidehydroxidephosphate3’-esterwith5,6-dimethyl-1-alpha-d-ribofuranos
- Cyanocobalamin Impurity 13
- oxolamine(arcum)
- ALPHA-(5,6-DIMETHYLBENZIMIDAZOLYL)HYDROXOCOBAMIDE HYDROCHLORIDE
- VITAMIN B12A HYDROCHLORIDE
- depogamma
- docelvita
- Cobinamide, Co-hydroxy-, f-(dihydrogen phosphate), inner salt, 3-ester with (5,6-dimethyl-1-.alpha.-D-ribofuranosyl-1H-benzimidazole-.kappa.N3)
- ciplaminh
- HYDROXOCOBALAMIN,USP
- alpha-(5,6-dimethylbenzimidazolyl)hydroxocobamide
- hydroxyvitaminb12
- primabaltrp
- HYDROXOCOBALAMIN HYDROCHLORIDE
- VITAMIN B12B
- Hydroxocobalamin (~90%)
- cobinamide,dihydroxide,dihydrogenphosphate(ester),mono(innersalt),3’-e
- hydrobamine
- Hydroxocobalam
- HydroxocobalaMin (VitaMin B12a)
- redisolh
- AQUOCOBALAMIN CHLORIDE
- Hydroxocobalamin/VitaminB12Cp2000
- Ver mais sinónimos
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9 produtos.
Hydroxocobalamin
CAS:Hydroxocobalamin (Vitamin B12a) is a naturally occurring, injectable form of vitamin B12 used as a dietary supplement to treat B12 deficiency, includingFórmula:C62H89CoN13O15PPureza:98%Cor e Forma:SolidPeso molecular:1346.36Hydroxocobalamin (>90%)
CAS:<p>Stability Hygroscopic<br>Applications Hydroxocobalamin is an intermediate in the synthesis of Nitritocobalamin(N490240) is a useful synthetic intermediate in the synthesis of Hydroxocobalamin Acetate (H826800); a physiological analog of vitamin B12 where the CN group is replaced with OH. Exists in aqueous solution as an equilibrium mixture of the hydroxy isomer and the ionic aqua isomer (aquacobalamin). Precursor of the coenzymes methylcobalamin and cobamamide. Coordination Compound. Vitamin (hematopoietic).<br>References Kaczka, E.A., et al.: Science, 112, 354 (1950); Friedrich, W., et al.: Vitamins, 837 (1988); Forsyth, J.C., et al.: Clin. Toxicol., 31, 277 (1993)<br></p>Fórmula:C62H89CoN13O15PPureza:>90%Cor e Forma:NeatPeso molecular:1346.36Hydroxocobalamin
CAS:<p>Hydroxocobalamin is a vitamin that has a specific antidote for cyanide poisoning. Hydroxocobalamin is synthesized from hydroxycobalamin, which is produced by the reaction of cyanide with cytochrome c in the presence of ferric ion, and it can be administered orally or intravenously. Hydroxocobalamin reacts with cyanide to form cyanocobalamin and releases the toxic hydrogen cyanide gas as a by-product. Hydroxocobalamin also has effects on cardiac tissue as it increases mitochondrial cytochrome C oxidase activity. The thermodynamic data for hydroxocobalamin are not available because this compound is unstable in water.</p>Fórmula:C62H89CoN13O15PPureza:90%MinCor e Forma:PowderPeso molecular:1,346.35 g/molCobinamide, Co-hydroxy-, f-(dihydrogen phosphate), inner salt, 3'-esterwith (5,6-dimethyl-1-a-D-ribofuranosyl-1H-benzimidazole-kN3)
CAS:Fórmula:C62H89CoN13O15PPureza:98%Cor e Forma:SolidPeso molecular:1346.3551Ref: 4Z-V-035017
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