CAS 13422-55-4

Metilcobalamina

Descrição:

Metilcobalamina, com o número CAS 13422-55-4, é uma forma biologicamente ativa da vitamina B12, também conhecida como cobalamina. É uma vitamina solúvel em água que desempenha um papel crucial em vários processos fisiológicos, incluindo a síntese de DNA, a formação de glóbulos vermelhos e a função neurológica. Metilcobalamina é caracterizada por sua estrutura de anel corrin contendo cobalto, que é essencial para sua atividade biológica. É frequentemente usada como suplemento dietético e é particularmente importante para indivíduos com deficiência de vitamina B12, que pode levar à anemia e problemas neurológicos. Metilcobalamina é conhecido por sua capacidade de atravessar a barreira hematoencefálica, tornando-se benéfico para a saúde neurológica. Em termos de estabilidade, é sensível à luz e ao calor, o que pode afetar sua potência. A substância é tipicamente administrada por meio de suplementos orais ou injeções, dependendo das necessidades do indivíduo. No geral, Metilcobalamina é vital para manter uma função nervosa saudável e processos metabólicos no corpo.

Fórmula: C₆₃H₉₁CoN₁₃O₁₄P

InChI: InChI=1S/C62H90N13O14P.CH3.Co/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);1H3;/q;-1;+3/p-2/t31-,34-,35-,36-,37+,41-,52?,53-,56+,57+,59-,60+,61+,62+;;/m1../s1

Chave InChI: InChIKey=ZFLASALABLFSNM-FGIXMQGJSA-L

SMILES: [CH3-][Co+3]1234[N]=5[C@@]6(C)[C@]7([N-]1C([C@@](C)([C@H]7CC(N)=O)CCC(=O)NC[C@@H](C)OP(=O)([O-])O[C@H]8C(O)([C@@H](N9C=[N]2C=%10C9=CC(C)=C(C)C%10)O[C@@H]8CO)[H])=C(C)C%11=[N]3C(=CC%12=[N]4C(=C(C)C5[C@@H](CCC(N)=O)[C@@]6(CC(N)=O)C)[C@](CC(N)=O)(C)[C@@H]%12CCC(N)=O)C(C)(C)[C@@H]%11CCC(N)=O)[H]

Sinónimos:

• Algobaz
• Co-Methylcobalamin
• Cobalamin, Co-methyl-
• Cobinamide, Co-methyl deriv., hydroxide, dihydrogen phosphate (ester), inner salt, 3'-ester with 5,6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole
• Cobinamide, Co-methyl deriv., hydroxide, dihydrogen phosphate (ester), inner salt, 3'-ester with 5,6-dimethyl-1-α-D-ribofuranosylbenzimidazole
• Cobinamide, Co-methyl deriv., hydroxide, dihydrogen phosphate (ester), inner salt, 3′-ester with 5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosyl-1H-benzimidazole
• Cobinamide, Co-methyl deriv., hydroxide, dihydrogen phosphate (ester), inner salt, 3′-ester with 5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosylbenzimidazole
• Cobinamide, Co-methyl derivative, hydroxide, dihydrogen phosphate (ester), inner salt, 3'-ester with 5,6-dimethyl-1-α-D-ribofuranosyl-1H-benzimidazole
• Cobinamide, Co-methyl-, dihydrogen phosphate (ester), inner salt, 3′-ester with (5,6-dimethyl-1-α-<span class="text-smallcaps">D</span>-ribofuranosyl-1H-benzimidazole-κN³)
• Hitocobamin M
• MeCbl
• Mecobalamin
• Mecobalamina
• Mecobalamine
• Methycobal
• Methyl cobalamine
• Methyl vitamin B12
• Methyl vitamin B₁₂
• Methyl-5,6-dimethylbenzimidazolylcobalamin
• Methyl-B12
• Methyl-B₁₂
• Methylcob(III)alamin
• Methylcobalamin
• Methylcobaz

Methylcobalamin Hydrate

CAS: 13422-55-4, 288315-09-3

Fórmula: C₆₃H₉₁CoN₁₃O₁₄P·xH₂O

Pureza: >98.0%(N)

Cor e Forma: Red to Dark red to Brown powder to crystal

Peso molecular: 1,344.40 (as Anhydrous)

Ref: 3B-M2742

Methylcobalamin

CAS: 13422-55-4

Vitamin b12 (cyanocobalamin and related compounds with vitamin b12 activity) and its derivatives

Fórmula: C₆₃H₉₁CoN₁₃O₁₄P

Cor e Forma: Dark Red Powder

Peso molecular: 1343.5878

Ref: 45-1424550

Methylcobalamin

CAS: 13422-55-4

Fórmula: C₆₃H₉₁CoN₁₃O₁₄P

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 1344.3823

Ref: IN-DA003S3I

Methylcobalamin-d3

CAS: 13422-55-4

Fórmula: C₆₃H₈₈D₃CoN₁₃O₁₄P

Peso molecular: 1347.42

Ref: 4Z-V-035018

Methylcobalamin hydrate

CAS: 13422-55-4

Fórmula: C₆₃H₉₁CoN₁₃O₁₄P·xH₂O

Pureza: 98.0 - 102.0 % (dried basis)

Cor e Forma: Dark red crystalline powder or crystals

Peso molecular: 1344.41 (anhydrous)

Ref: 7W-GV9033

Methylcobalamin

CAS: 13422-55-4

Fórmula: C₆₃H₉₁CoN₁₃O₁₄P

Cor e Forma: Neat

Peso molecular: 1344.38

Ref: 04-C15084870

Methylcobalamin

CAS: 13422-55-4

Methylcobalamin, a B12 form, aids homocysteine metabolism; treats nutritional issues, Alzheimer's, and rheumatoid arthritis.

Fórmula: C₆₃H₉₁CoN₁₃O₁₄P

Pureza: 98% - 98.23%

Cor e Forma: Solid

Peso molecular: 1344.38

Ref: TM-T3136

Methylcobalamin-13C-d3

CAS: 13422-55-4

Fórmula: CC₆₂H₈₈D₃CoN₁₃O₁₄P

Peso molecular: 1348.42

Ref: 4Z-V-035006

Mecobalamin RS

CAS: 13422-55-4

Cor e Forma: Dark Red

Ref: 2K-1159000021

Mecobalamin-d3

Produto Controlado

CAS: 13422-55-4

Stability Light Sensitive
Applications Isotope labelled Mecobalamin (M202800), one of the biologically active forms of vitamin B12; differing only by the substitution of a methyl for the cyano group. Coenzyme required in the biosynthesis of methionine. Vitamin (hematopoietic).
References Kisliuk, R.L., Biochem. J., 75, 467 (1960), Guest, J.R., et al.: Nature, 195, 340 (1962), Dolphin, D., et al.: Methods Enzymol., 18, 34 (1971), Beck, W.S., et al.: Am. J. Hematol., 34, 83 (1990),

Fórmula: C₆₃H₈₈D₃CoN₁₃O₁₄P

Cor e Forma: Dark Red

Peso molecular: 1347.4

Ref: TR-M202802

Mecobalamin

CAS: 13422-55-4

Stability Light Sensitie
Applications One of the biologically active forms of vitamin B12; differing only by the substitution of a methyl for the cyano group. Coenzyme required in the biosynthesis of methionine. Vitamin (hematopoietic).
References Kisliuk, R.L., Biochem. J., 75, 467 (1960), Guest, J.R., et al.: Nature, 195, 340 (1962), Dolphin, D., et al.: Methods Enzymol., 18, 34 (1971), Beck, W.S., et al.: Am. J. Hematol., 34, 83 (1990),

Fórmula: C₆₃H₉₁CoN₁₃O₁₄P

Cor e Forma: Neat

Peso molecular: 1344.38

Ref: TR-M202800

Mecobalamin

CAS: 13422-55-4

Mecobalamin is a form of vitamin B12 that is used to treat bowel disease. It binds to the target enzymes methionine synthase and cystathionine beta-synthase, which are involved in the synthesis of methionine and cysteine respectively. Mecobalamin has been shown to be effective in treating Crohn's disease when given as a low-dose therapy. Mecobalamin also has demonstrated therapeutic effects in ulcerative colitis, but had no effect on patients with non-ulcerative colitis. Mecobalamin was well tolerated at the doses tested and did not produce any significant changes in blood cell counts or liver enzyme activities.
Mecobalamin is not absorbed orally, so it is given by injection or intravenously. The drug can be injected subcutaneously, intramuscularly, or intravenously.

Fórmula: C₆₃H₉₁CoN₁₃O₁₄P

Pureza: Min. 95%

Cor e Forma: Red Powder

Peso molecular: 1,344.38 g/mol

Ref: 3D-FM25030

Vitamin B12a (B12 Analog) ExiPlus, Multi-Compendial, 98%-102%

CAS: 13422-55-4

Fórmula: C₆₃H₉₁CoN₁₃O₁₄P

Pureza: 98 - 102%

Cor e Forma: Dark red, Crystalline powder, Clear, Red

Peso molecular: 1355.38

Ref: SR-79446

Mecobalamin-13CD3

Produto Controlado

CAS: 13422-55-4

Fórmula: C₆₂CH₈₈D₃CoN₁₃O₁₄P

Cor e Forma: Neat

Peso molecular: 1348.42

Ref: TR-M202801