
CAS 1343040-07-2
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4 produtos.
2-{cyclopentyl[(9H-fluoren-9-ylmethoxy)carbonyl]amino}acetic acid
CAS:Fórmula:C22H23NO4Pureza:98%Peso molecular:365.4223N-(((9h-Fluoren-9-yl)methoxy)carbonyl)-N-cyclopentylglycine
CAS:N-(((9h-Fluoren-9-yl)methoxy)carbonyl)-N-cyclopentylglycinePureza:98%Peso molecular:365.42g/mol2-{Cyclopentyl[(9H-fluoren-9-ylmethoxy)carbonyl]amino}acetic acid
CAS:The synthesis of 2-{Cyclopentyl[(9H-fluoren-9-ylmethoxy)carbonyl]amino}acetic acid is accomplished through an asymmetric, stereoselective, catalytic route. The first step in the synthesis is conversion of glycine to the corresponding N-protected glycine methyl ester by reaction with benzyl chloroformate followed by protection of both carboxylic acid groups as FMOC derivatives. The key steps are a diastereoselective hydrogenation of the cyclopentane ring system and an efficient alkylation reaction of the resulting alcohol with 9H-fluoren-9-ol. 2-[Cyclopentyl[(9H-fluoren-9-ylmethoxy)carbonyl]amino]acetic acid has been shown to be a potent inhibitor against bacterial growth. It binds to bacterial topoisomerase IV enzyme, whichFórmula:C22H23NO4Pureza:Min. 95%Peso molecular:365.4 g/mol



