CAS 1349723-93-8

Elacestrant DiHCl

CAS: 1349723-93-8

Fórmula: C₃₀H₃₈N₂O₂·2HCl

Peso molecular: 458.65 2*36.46

Ref: 4Z-E-242001

Elacestrant dihydrochloride

CAS: 1349723-93-8

Elacestrant dihydrochloride

Pureza: ≥98%

Peso molecular: 531.56g/mol

Ref: 54-BUP12719

Elacestrant dihydrochloride

CAS: 1349723-93-8

Elacestrant dihydrochloride (DA-DKRAD1901 dihydrochloride) is an orally available selective estrogen receptor degrader with IC50s of 48 for ERα and 870 nM for

Fórmula: C₃₀H₄₀Cl₂N₂O₂

Pureza: 99.59% - >99.99%

Cor e Forma: Solid

Peso molecular: 531.56

Ref: TM-T13675

Elacestrant dihydrochloride

Produto Controlado

CAS: 1349723-93-8

Elacestrant dihydrochloride is a potential drug for the treatment of breast cancer. This agent has been shown to inhibit the activity of CDK4/6, which are enzymes that regulate the cell cycle and prevent progression from G1 to S phase. Elacestrant dihydrochloride also causes apoptosis in tumor cells by binding to death receptors, causing them to trigger the release of proteins that activate apoptosis. The uptake of elacestrant dihydrochloride into tumor cells is increased by epidermal growth factor (EGF) and other receptor binding drugs. A study found that elacestrant dihydrochloride at a dose of 100 mg/kg was effective in reducing tumor growth in xenograft mice models when combined with palbociclib.

Fórmula: C₃₀H₄₀Cl₂N₂O₂

Pureza: Min. 95%

Peso molecular: 531.56 g/mol

Ref: 3D-FE177759