CAS 135-16-0

Ácido tetrahidrofólico

Descrição:

Ácido tetrahidrofólico, também conhecido como tetrahidrofolato (THF), é um derivado da vitamina B solúvel em água que desempenha um papel crucial no metabolismo celular, particularmente na síntese de ácidos nucleicos e aminoácidos. É a forma ativa do folato, que é essencial para a síntese, reparo e metilação do DNA, tornando-o vital para a divisão e crescimento celular. Ácido tetrahidrofólico é caracterizado por sua capacidade de aceitar e doar unidades de um carbono em várias reações bioquímicas, facilitando a conversão de homocisteína em metionina e a síntese de purinas e timidina. O composto é tipicamente encontrado no corpo como uma coenzima na forma de vários derivados de poliglutamato, aumentando sua estabilidade e atividade. Em termos de propriedades físicas, Ácido tetrahidrofólico é um pó cristalino de amarelo pálido a laranja que é solúvel em água, mas relativamente insolúvel em solventes orgânicos. Sua deficiência pode levar à anemia megaloblástica e outros problemas de saúde, sublinhando sua importância na nutrição e saúde.

Fórmula: C₁₉H₂₃N₇O₆

InChI: InChI=1S/C19H23N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,11-12,21,23H,5-8H2,(H,24,29)(H,27,28)(H,31,32)(H4,20,22,25,26,30)/t11?,12-/m0/s1

Chave InChI: InChIKey=MSTNYGQPCMXVAQ-KIYNQFGBSA-N

SMILES: O=C1C2=C(NCC(CNC3=CC=C(C(N[C@@H](CCC(O)=O)C(O)=O)=O)C=C3)N2)NC(N)=N1

Sinónimos:

• (-)-<span class="text-smallcaps">L</span>-5,6,7,8-Tetrahydrofolic acid
• (-)-L-5,6,7,8-Tetrahydrofolic acid
• (2S)-2-(4-(((2-Imino-4-oxo-1,2,3,4,5,6,7,8-octahydropteridin-6-yl)methyl)amino)benzamido)pentanedioic acid
• 5,6,7,8-Tetrahydrofolic acid
• <span class="text-smallcaps">L</span>-Glutamic acid, N-[4-[[(2-amino-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-
• <span class="text-smallcaps">L</span>-Glutamic acid, N-[4-[[(2-amino-3,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-
• Glutamic acid, N-[p-[[(2-amino-3,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-, <span class="text-smallcaps">L</span>-
• Glutamic acid, N-[p-[[(2-amino-3,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-, L-
• L-Glutamic acid, N-[4-[[(2-amino-3,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-
• N-[4-[[(2-Amino-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutaminsaure
• N-[4-[[(2-Amino-3,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-<span class="text-smallcaps">L</span>-glutamic acid
• N-[4-[[(2-amino-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
• Tetrahydrofolic acid
• Tetrahydropteroylglutamic acid
• Thfa
• acide N-[4-[[(2-amino-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamique
• acido N-[4-[[(2-amino-1,4,5,6,7,8-hexahidro-4-oxo-6-pteridinil)metil]amino]benzoil]-L-glutamico
• L-Glutamic acid, N-[4-[[(2-amino-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-

Tetrahydrofolic acid

CAS: 135-16-0

Fórmula: C₁₉H₂₃N₇O₆

Pureza: 67%

Cor e Forma: Solid

Peso molecular: 445.4292

Ref: IN-DA009BK3

Tetrahydrofolic acid

CAS: 135-16-0

Tetrahydrofolic acid

Fórmula: C₁₉H₂₃N₇O₆

Pureza: 67%

Cor e Forma: brown solid

Peso molecular: 445.43g/mol

Ref: 54-BIT3012

Tetrahydrofolic acid

CAS: 135-16-0

Fórmula: C₁₉H₂₃N₇O₆

Pureza: ≥ 65%

Cor e Forma: Faint yellow, faint brown or brown powder or solid

Peso molecular: 445.43

Ref: 7W-GV7828

Tetrahydrofolic acid

CAS: 135-16-0

Tetrahydrofolic acid (5,6,7,8-tetrahydrofolic acid) is a VB9 derivative that is a common one-carbon donor in organisms and is involved in growth and metabolism.

Fórmula: C₁₉H₂₃N₇O₆

Pureza: 94.10% - 94.61%

Cor e Forma: Solid

Peso molecular: 445.43

Ref: TM-T21367

Tetrahydrofolic Acid

CAS: 135-16-0

Fórmula: C₁₉H₂₃N₇O₆

Peso molecular: 445.44

Ref: 4Z-F-2419

L-Tetrahydrofolic Acid (>70% when packaged)

Produto Controlado

CAS: 135-16-0

Stability We have observed that this material decomposes steadily over time. Use immediate
Applications L-Tetrahydrofolic Acid is a folic acid derivative and coenzyme involved in the metabolism of amino and nucleic acids. We have observed that this material decomposes steadily over time. Use immediately upon receipt.
References Prinz-Langenohl, R., et al.: Brit. J. Pharmacol., 158, 2014 (2009), Martin, H., et al.: Anal. Biochem., 402, 137 (2010), Dasarathy, J., et al.: Am. J. Clin. Nut., 91, 357 (2010), Karas-Kuzelicki, N., et al.: Clin. Biochem., 43, 37 (2010),

Fórmula: C₁₉H₂₃N₇O₆

Cor e Forma: Neat

Peso molecular: 445.43

Ref: TR-T293515

Tetrahydrofolic Acid

CAS: 135-16-0

Pureza: 67.0%

Peso molecular: 445.436

Ref: 10-F544915

Tetrahydrofolic acid

CAS: 135-16-0

Tetrahydrofolic acid is a water-soluble sodium salt that is found in the form of tetrahydrofolate (THF) in the human body. It is involved in the synthesis of DNA and other biomolecules. Tetrahydrofolic acid has been used as an antimicrobial agent, mainly to inhibit bacterial growth. In wastewater treatment, tetrahydrofolic acid has been shown to have a matrix effect on polymerization reactions and transfer reactions. Tetrahydrofolic acid can also be used as a reagent for analytical methods and reaction solutions for enzymes with THF as a substrate. The enzyme activities are glycol ethers with THF as a cofactor. Tetrahydrofolic acid can be used in model systems to study enzyme kinetics or enzymatic mechanisms.

Fórmula: C₁₉H₂₃N₇O₆

Pureza: 65%Min

Peso molecular: 445.43 g/mol

Ref: 3D-FT165435

L-Tetrahydrofolic Acid

CAS: 135-16-0

Fórmula: C₁₉H₂₃N₇O₆

Peso molecular: 445.40

Ref: ST-EA-CP-F5018