CAS 135620-04-1

Catalisador S,S-Jacobsen

Descrição:

Catalisador S,S-Jacobsen, também conhecido como catalisador de Jacobsen, é um complexo quiral de manganês(III) amplamente utilizado em catálise assimétrica, particularmente para a epoxidação de alcenos. Este catalisador é caracterizado por sua estrutura de ligante quiral única, que geralmente inclui uma estrutura do tipo salen, permitindo facilitar reações enantiosseletivas. O centro de manganês no complexo desempenha um papel crucial na ativação do oxidante, muitas vezes um perácido, para gerar uma espécie eletrofílica que pode reagir seletivamente com o substrato de alceno. A configuração S,S do ligante confere quiralidade, permitindo a formação de produtos enantiomericamente enriquecidos. O catalisador é conhecido por sua alta eficiência e seletividade, tornando-o valioso na química orgânica sintética, especialmente na produção de produtos farmacêuticos e químicos finos. Além disso, o catalisador pode ser utilizado em condições de reação brandas, o que é vantajoso para preservar grupos funcionais sensíveis nos substratos. Sua versatilidade e eficácia o tornaram uma escolha proeminente no campo da síntese assimétrica.

Fórmula: C₃₆H₅₂ClMnN₂O₂

InChI: InChI=1S/C36H54N2O2.ClH.Mn/c1-33(2,3)25-17-23(31(39)27(19-25)35(7,8)9)21-37-29-15-13-14-16-30(29)38-22-24-18-26(34(4,5)6)20-28(32(24)40)36(10,11)12;;/h17-22,29-30,39-40H,13-16H2,1-12H3;1H;/q;;+3/p-3/t29-,30-;;/m0../s1

Chave InChI: InChIKey=LJVAWOSDJSQANR-ARDORAJISA-K

SMILES: [Cl-][Mn+3]123[N]([C@@]4([C@@]([N]1=CC=5C([O-]2)=C(C(C)(C)C)C=C(C(C)(C)C)C5)(CCCC4)[H])[H])=CC=6C([O-]3)=C(C(C)(C)C)C=C(C(C)(C)C)C6

Sinónimos:

• (+)-Bis(3,5-Di-T-Bu-Salicyl.)-1,2-Cyclo-Hexanediamino-Mn Cl
• (-)-Bis(3,5-Di-T-Bu-Salicyl.)-1,2-Cyclo-
• (1R,2R)-(-)-[1,2-Cyclohexanediamino-N,N'-BIS(3,5-DI-T-Butylsalicylidene)]MANGANESE(III)CHLORIDE
• (1S,2S)-(+)-[1,2-Cyclohexanediamino-N,N'-BIS(3,5-DI-T-Butylsalicylidene)]manganese (III) chloride
• (R,R)-(-)-N,N'-BIS(3.5-DI-T-Butylsalicylidene)-1,2-CYCLOHEXANEDIAMINE-manganese (III) chloride
• (R,R)-Jacobsen Cat.
• (R,R)-Jacobsen Catalyst
• (R,R)-Jacobsen'S Catalyst
• (R,R)-Jacobsen'S Catalyst Manganese(Iii) Chloride Complex
• (S,S)-(+)-N,N'-BIS(3,5-DI-TERT-Butylsalicylidene)-1,2-Cyclohexanediamino-MANGANESE(III) CHLORIDE
• (S,S)-(+)-N,N′-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediamino manganese(II) chloride
• (S,S)-(+)-N,N′-Bis(3,5-di-tert-butylsalicylidene)-1,2-diaminocyclohexylmanganese(III) chloride
• (S,S)-Jacobsen Cat.
• (S,S)-Jacobsen Catalyst
• (S,S)-Jacobsen'S Catalyst
• (S,S)-Jacobsen'S Catalyst Manganese(Iii) Chloride Complex
• (S,S)-N,N'-BIS(3,5-DI-TERT-BUTYLSALICYL-IDENE)-1,2-Cyclohexanediamino-MN-CL
• (S,S)-[N,N′-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediamine]manganese(III) chloride
• (SP-5-13)-Chloro[[2,2′-[(1S,2S)-1,2-cyclohexanediylbis[(nitrilo-κN)methylidyne]]bis[4,6-bis(1,1-dimethylethyl)phenolato-κO]](2-)]manganese
• 2,2'-{(1R,2R)-cyclohexane-1,2-diylbis[nitrilo(E)methylylidene]}bis(4,6-di-tert-butylphenol)-trichloromanganese (1:1)
• 2,2'-{(1S,2S)-cyclohexane-1,2-diylbis[nitrilo(E)methylylidene]}bis(4,6-di-tert-butylphenol)-trichloromanganese (1:1)
• Jacobsen'S Catalyst
• Kjb 002
• Manganese, chloro[[2,2′-[(1S,2S)-1,2-cyclohexanediylbis[(nitrilo-κN)methylidyne]]bis[4,6-bis(1,1-dimethylethyl)phenolato-κO]](2-)]-, (SP-5-13)-
• Manganese, chloro[[2,2′-[1,2-cyclohexanediylbis(nitrilomethylidyne)]bis[4,6-bis(1,1-dimethylethyl)phenolato]](2-)-N,N′,O,O′]-, [SP-5-13-(1S-trans)]-
• Manganese, chloro[[2,2′-[1,2-cyclohexanediylbis[(nitrilo-κN)methylidyne]]bis[4,6-bis(1,1-dimethylethyl)phenolato-κO]](2-)]-, [SP-5-13-(1S-trans)]-

(1S,2S)-(+)-[1,2-Cyclohexanediamino-N,N'-bis(3,5-di-t-butylsalicylidene)]manganese(III) chloride, 98% (S,S)-Jacobsen Cat.

CAS: 135620-04-1

(1S,2S)-(+)-[1,2-Cyclohexanediamino-N,N'-bis(3,5-di-t-butylsalicylidene)]manganese(III) chloride, 98% (S,S)-Jacobsen Cat.

Fórmula: C₃₆H₅₂ClMnN₂O₂

Pureza: 98%

Cor e Forma: brown pwdr.

Peso molecular: 635.22

Ref: 08-25-0301

(S,S)-(+)-N,N'-BIS(3,5-DI-TERT-BUTYLSALICYLIDENE)-1,2-CYCLOHEXANEDIAMINO-MANGANESE(III) CHLORIDE

CAS: 135620-04-1

Fórmula: C₃₆H₅₂ClMnN₂O₂

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 635.2013

Ref: IN-DA003COV

(S,S)-[N,N’-Bis(3,5-Di-Tert-Butylsalicylidene)-1,2-Cyclohexanediamine]Manganese(Iii) Chloride

CAS: 135620-04-1

(S,S)-[N,N’-Bis(3,5-Di-Tert-Butylsalicylidene)-1,2-Cyclohexanediamine]Manganese(Iii) Chloride

Pureza: 98%

Peso molecular: 708.12g/mol

Ref: 54-IN10302

(S,S)-(+)-N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminomanganese(III) chloride

CAS: 135620-04-1

The preparation of racemic N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminomanganese(III) chloride (S,S)-(+)-N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminomanganese(III) chloride is carried out by the reaction of salicyaldehyde with manganese dioxide in acetonitrile. The mixture is heated to reflux for 3 hours. The product is purified by recrystallization from hot acetonitrile and then purified again by preparative thin layer chromatography using a chiral stationary phase. The product is obtained as a white powder in an overall yield of 52%.
The synthesis of (R)-(-)-N-(3,5-Di-tert-butylsalicyl

Fórmula: C₃₆H₅₂ClMnN₂O₂

Cor e Forma: Powder

Peso molecular: 635.2 g/mol

Ref: 3D-FB29346

(S,S)-[N,N’-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediamine]manganese(III) chloride

CAS: 135620-04-1

Pureza: 97%

Peso molecular: 634.31

Ref: 10-F551685