CAS 1357576-48-7

AZD4320

CAS: 1357576-48-7

AZD4320 inhibits BCL2/BCLxL; IC50: KPUM-MS3=26nM, KPUM-UH1=17nM, STR-428=170nM.

Fórmula: C₄₅H₄₈ClF₃N₄O₇S₃

Pureza: 98.13% - 99.71%

Cor e Forma: Solid

Peso molecular: 945.53

Ref: TM-T14376

AZD4320

CAS: 1357576-48-7

AZD4320

Pureza: ≥98%

Peso molecular: 945.53g/mol

Ref: 54-BUP04825

AZD 4320-d4

CAS: 1357576-48-7

Fórmula: C₄₅H₄₄D₄ClF₃N₄O₇S₃

Peso molecular: 949.55

Ref: 4Z-A-272002

AZD 4320

CAS: 1357576-48-7

Fórmula: C₄₅H₄₈ClF₃N₄O₇S₃

Peso molecular: 945.53

Ref: 4Z-A-272001

AZD4320

CAS: 1357576-48-7

AZD4320 is a molecule that binds to the CDK4/CDK6 complex, which controls the cell cycle. AZD4320 has been shown to induce apoptosis in cancer cells by triggering mitochondrial membrane depolarization and long-term treatment of chronic lymphocytic leukemia. AZD4320 also inhibits the proliferation of leukemic cells by binding to CDK4/CDK6. This agent has potential as an anti-leukemic drug because it can be used in combination with monoclonal antibodies and thrombocytopenia drugs.

Fórmula: C₄₅H₄₈ClF₃N₄O₇S₃

Pureza: Min. 95%

Peso molecular: 945.5 g/mol

Ref: 3D-HEC57648