CAS 1362850-20-1

Seletalisib

CAS: 1362850-20-1

Fórmula: C₂₃H₁₄ClF₃N₆O

Pureza: 99%

Cor e Forma: Solid

Peso molecular: 482.8451

Ref: IN-DA01EOAJ

Seletalisib

CAS: 1362850-20-1

Seletalisib

Pureza: ≥95%

Peso molecular: 482.85g/mol

Ref: 54-BUP04946

(R)-3-(8-Chloro-3-(2,2,2-Trifluoro-1-(Pyrido[3,2-D]Pyrimidin-4-Ylamino)Ethyl)Quinolin-2-Yl)Pyridine 1-Oxide

CAS: 1362850-20-1

(R)-3-(8-Chloro-3-(2,2,2-Trifluoro-1-(Pyrido[3,2-D]Pyrimidin-4-Ylamino)Ethyl)Quinolin-2-Yl)Pyridine 1-Oxide

Pureza: 98+%

Peso molecular: 482.85g/mol

Ref: 54-PC108594

Seletalisib

CAS: 1362850-20-1

Seletalisib (UCB5857) (UCB5857) is a potent and specific PI3Kδ inhibitor (IC50: 12 nM).

Fórmula: C₂₃H₁₄ClF₃N₆O

Pureza: 99.81%

Cor e Forma: Solid

Peso molecular: 482.85

Ref: TM-TQ0044

Seletalisib (UCB-5857)

CAS: 1362850-20-1

Seletalisib is a novel, potent, and selective inhibitor of the lipid kinase activity. It blocks protein synthesis by binding to the ribosomal protein S6 kinase-1 (RSK1) which is involved in regulating cell proliferation and differentiation. Seletalisib has been shown to be effective in clinical studies for treatment of autoimmune diseases such as systemic lupus erythematosus (SLE). This drug also has pharmacokinetic properties that are suitable for hepatic impairment. Seletalisib also inhibits the production of chemokines, which are inflammatory cytokines that induce chemotaxis of leukocytes and promote inflammation.

Fórmula: C₂₃H₁₄ClF₃N₆O

Pureza: Min. 95%

Peso molecular: 482.85 g/mol

Ref: 3D-MEC85020