CAS 137017-45-9

Cytidine, 2'-deoxy-5-formyl-

CAS: 137017-45-9

Fórmula: C₁₀H₁₃N₃O₅

Pureza: 98%

Peso molecular: 255.2273

Ref: IN-DA0012PF

4-Amino-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidine-5-carbaldehyde

CAS: 137017-45-9

4-Amino-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidine-5-carbaldehyde

Pureza: 98%

Peso molecular: 255.23g/mol

Ref: 54-OR1062323

2''-Deoxy-5-formylcytidine

CAS: 137017-45-9

Fórmula: C₁₀H₁₃N₃O₅

Pureza: ≥ 98.0%

Cor e Forma: White to off-white solid

Peso molecular: 255.23

Ref: 7W-GW1127

2'-Deoxy-5-formyl-cytidine

Produto Controlado

CAS: 137017-45-9

Applications 2'-Deoxy-5-formyl-cytidine is a nucleotide derivative found in embryonic stem cell DNA.
References Pfaffeneder, T., et al.: Angew. Chem. Int. Edit., 50, 7008-7012 (2011)

Fórmula: C₁₀H₁₃N₃O₅

Cor e Forma: Neat

Peso molecular: 255.227

Ref: TR-D239810

2'-Deoxy-5-formylcytidine

CAS: 137017-45-9

2'-Deoxy-5-formylcytidine is a nucleoside analog that is used as a chemotherapeutic agent. It is cytotoxic to cells by binding to DNA and preventing the synthesis of DNA, RNA, and protein. The drug has been shown to induce cellular senescence in human fibroblasts, which can be reversed by the addition of deuterium. 2'-Deoxy-5-formylcytidine also inhibits the production of reactive oxygen species (ROS) by inducing the expression of antioxidant enzymes such as superoxide dismutase 2 and glutathione peroxidase 1. The oxidation products are misincorporated into DNA strands, leading to intramolecular hydrogen bonds with cytosine bases. These modifications lead to denaturation of DNA and inhibition of transcription and replication.
2'-Deoxy-5-formylcytidine also interacts with oligodeoxynucleotides, which leads to misinc

Fórmula: C₁₀H₁₃N₃O₅

Pureza: Min. 97 Area-%

Cor e Forma: White Powder

Peso molecular: 255.23 g/mol

Ref: 3D-ND63556

2'-Deoxy-5-formyl-cytidine-1,3-15N2,2-13C

Produto Controlado

CAS: 137017-45-9

Fórmula: CC₉H₁₃₁₅N₂NO₅

Cor e Forma: Neat

Peso molecular: 258.207

Ref: TR-D239812