CAS 13726-69-7

1-(1,1-Dimetiletil) (2S,4R)-4-hidroxi-1,2-pirrolidinedicarboxilato

Descrição:

1-(1,1-Dimetiletil) (2S,4R)-4-hidroxi-1,2-pirrolidinedicarboxilato, com número CAS 13726-69-7, é um composto químico caracterizado por sua estrutura de pirrolidina, que apresenta dois grupos carboxilato e um grupo hidroxila. Este composto é um derivado da pirrolidina, um heterociclo de cinco membros que contém nitrogênio, e é notável por sua estereoquímica, especificamente a configuração (2S,4R), que indica a disposição espacial de seus substituintes. A presença do grupo tert-butilo (1,1-dimetiletil) contribui para suas características hidrofóbicas, influenciando sua solubilidade e reatividade. O grupo hidroxila melhora seu potencial para a formação de ligações de hidrogênio, o que pode afetar suas interações em sistemas biológicos. Este composto pode ser de interesse em química medicinal e síntese orgânica devido às suas características estruturais, que podem conferir atividades biológicas específicas ou servir como intermediários na síntese de moléculas mais complexas. Assim como muitos compostos orgânicos, sua estabilidade, reatividade e aplicações potenciais dependeriam das condições específicas sob as quais é utilizado.

Fórmula: C₁₀H₁₇NO₅

InChI: InChI=1S/C10H17NO5/c1-10(2,3)16-9(15)11-5-6(12)4-7(11)8(13)14/h6-7,12H,4-5H2,1-3H3,(H,13,14)/t6-,7+/m1/s1

Chave InChI: InChIKey=BENKAPCDIOILGV-RQJHMYQMSA-N

SMILES: C(OC(C)(C)C)(=O)N1[C@H](C(O)=O)C[C@@H](O)C1

Sinónimos:

• (2S,4R)-1-(tert-butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylic acid
• (2S,4R)-1-(tertbutoxycarbonyl)-4-hydroxypyrrolidine carboxylic acid
• (2S,4R)-1-Boc-4-Hydroxy-Proline
• (2S,4R)-4-Hydroxy-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylic acid
• (2S,4R)-4-Hydroxy-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid
• (2S,4R)-4-Hydroxypyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester
• (2S,4R)-4-hydroxy-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester
• (2S,4R)-N-tert-Butoxycarbonyl-4-hydroxyproline
• (4R)-1-(tert-Butoxycarbonyl)-4-hydroxy-<span class="text-smallcaps">L</span>-proline
• (4R)-1-(tert-butoxycarbonyl)-4-hydroxy-L-proline
• 1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(1,1-dimethylethyl) ester, (2S,4R)-
• 1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(1,1-dimethylethyl) ester, (2S-trans)-
• 1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-tert-butyl ester, <span class="text-smallcaps">L</span>-
• 1-(1,1-Dimethylethyl) (2S,4R)-4-hydroxy-1,2-pyrrolidinedicarboxylate
• 1-(Tert-Butoxycarbonyl)-4-Hydroxyproline
• 1-(tert-Butoxycarbonyl)-(2S,4R)-4-hydroxypyrrolidine-2-carboxylic acid
• 4-Hydroxy-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester
• BOC-4-Hydroxy-L-Proline
• Boc-<span class="text-smallcaps">L</span>-trans-γ-hydroxyproline
• Boc-Hyp-OH
• Boc-L-Hyp-OHN-(tert-Butoxycarbonyl)-L-4-hydroxyproline
• Boc-trans-4-hydroxy-L-proline
• Boc-trans-Hydroxy-<span class="text-smallcaps">L</span>-proline
• N-(tert-Butoxycarbonyl)-4-hydroxy-<span class="text-smallcaps">L</span>-proline
• N-(tert-Butoxycarbonyl)hydroxy-<span class="text-smallcaps">L</span>-proline
• N-(tert-Butoxycarbonyl)hydroxyproline
• N-(tert-Butyloxycarbonyl)-4-hydroxyproline
• N-BOC-trans-4-hydroxy-L-proline
• N-Boc-trans-4-hydroxy-<span class="text-smallcaps">L</span>-proline
• N-T-bocl-hydroxyproline
• N-tert-Butoxycarbonyl trans-4-hydroxy-<span class="text-smallcaps">L</span>-proline
• N-tert-Butoxycarbonyl-(4R)-4-hydroxy-<span class="text-smallcaps">L</span>-proline
• NSC 343720
• trans-1-(tert-Butoxycarbonyl)-4-hydroxy-<span class="text-smallcaps">L</span>-proline
• 1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-tert-butyl ester, L-

trans-N-(tert-Butoxycarbonyl)-4-hydroxy-L-proline

CAS: 13726-69-7

Fórmula: C₁₀H₁₇NO₅

Pureza: >98.0%(T)(HPLC)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 231.25

Ref: 3B-B1635

N-Boc-trans-4-hydroxy-L-proline, 97%

CAS: 13726-69-7

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Fórmula: C₁₀H₁₇NO₅

Pureza: 97%

Cor e Forma: White, Powder

Peso molecular: 231.25

Ref: 02-H27110

N-Boc-(2S,4R)-4-hydroxyproline

CAS: 13726-69-7

Fórmula: C₁₀H₁₇NO₅

Pureza: 97%

Cor e Forma: Solid

Peso molecular: 231.2457

Ref: IN-DA0034K2

(2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acid, N-BOC protected

CAS: 13726-69-7

(2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acid, N-BOC protected

Fórmula: C₁₀H₁₇NO₅

Pureza: 97%

Cor e Forma: white/off white crystalline powder

Peso molecular: 231.24567g/mol

Ref: 54-OR307069

Boc-Hyp-OH

CAS: 13726-69-7

Fórmula: C₁₀H₁₇NO₅

Pureza: ≥ 98.0%

Cor e Forma: White powder

Peso molecular: 231.25

Ref: 7W-GM8684

Boc-L-Hydroxyproline

CAS: 13726-69-7

Fórmula: C₁₀H₁₇NO₅

Peso molecular: 231.25

Ref: 4Z-P-166029

Boc-Hyp-OH

CAS: 13726-69-7

M03213 - Boc-Hyp-OH

Fórmula: C₁₀H₁₇NO₅

Pureza: 97%

Cor e Forma: Crystalline Powder,Powder

Peso molecular: 231.248

Ref: 10-M03213

BOC-L-Hydroxyproline extrapure, 98%

CAS: 13726-69-7

Fórmula: C₁₀H₁₇NO₅

Pureza: min 98%

Cor e Forma: White to off white, Crystalline powder

Peso molecular: 231.25

Ref: SR-38544

Boc-trans-Hydroxy-L-proline

Produto Controlado

CAS: 13726-69-7

Applications boc-trans-Hydroxy-L-proline is used in the preparation of hydroxyproline derivatives. boc-trans-Hydroxy-L-proline is an intermediate in the synthesis of Fosinopril-d5 Sodium Salt (F727803), the labeled analogue of Fosinopril Sodium Salt (F727800), a phosphinic acid containing angiotensin converting enzyme (ACE) inhibitor. Antihypertensive.
References Nakanishi, K., et. al.: Peptide Sci., 47, 197 (2010); Singhvi, S.M., et al.: Br. J. Clin. Pharmacol., 25, 9 (1988); Sullivan, P.A., et al.: Am. J. Hypertension, 1, 280S (1988)

Fórmula: C₁₀H₁₇NO₅

Cor e Forma: Neat

Peso molecular: 231.25

Ref: TR-H952495