CAS 138605-00-2

β-Alanina, N,N-dimetil-, (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-(acetiloxi)-3-eteni-dodecahidro-10,10b-diidroxi-3,4a,7,7,10a-pentametil-1-oxo-1H-nafto[2,1-b]pirano-6-il éster, cloridrato (1:1)

Descrição:

A substância química conhecida como β-Alanina, N,N-dimetil-, com a estereoquímica especificada e o número CAS 138605-00-2, é um composto orgânico complexo caracterizado por sua estrutura intrincada, que inclui múltiplos centros quirais e grupos funcionais como ésteres e hidroxilas. Este composto é um derivado da β-alanina, um aminoácido que desempenha um papel em vários processos biológicos. A presença do grupo dimetil sugere uma lipofilicidade aumentada, o que pode influenciar sua solubilidade e atividade biológica. O grupo funcional éster indica uma reatividade potencial, particularmente em reações de hidrólise, que podem afetar sua estabilidade e biodisponibilidade. Além disso, a forma de cloridrato implica que o composto é um sal, provavelmente aumentando sua solubilidade em ambientes aquosos. No geral, as características estruturais únicas deste composto podem conferir propriedades farmacológicas específicas, tornando-o de interesse na química medicinal e bioquímica. No entanto, estudos detalhados seriam necessários para elucidar completamente sua atividade biológica e aplicações potenciais.

Fórmula: C₂₇H₄₃NO₈·ClH

InChI: InChI=1S/C27H43NO8.ClH/c1-10-24(5)15-18(31)27(33)25(6)17(30)11-13-23(3,4)21(25)20(35-19(32)12-14-28(8)9)22(34-16(2)29)26(27,7)36-24;/h10,17,20-22,30,33H,1,11-15H2,2-9H3;1H/t17-,20-,21-,22-,24-,25-,26+,27-;/m0./s1

Chave InChI: InChIKey=VIRRLEDAYYYTOD-YHEOSNBFSA-N

SMILES: O[C@@]12[C@]3(C)[C@@]([C@H](OC(CCN(C)C)=O)[C@H](OC(C)=O)[C@@]1(C)O[C@](C=C)(C)CC2=O)(C(C)(C)CC[C@@H]3O)[H].Cl

Sinónimos:

• (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-3-ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxododecahydro-1H-benzo[f]chromen-5-yl acetate
• (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-(acetyloxy)-3-ethenyl-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxododecahydro-1H-benzo[f]chromen-6-yl 4-methylpentanoate hydrochloride (1:1)
• (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-(acetyloxy)-3-ethenyl-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxododecahydro-1H-benzo[f]chromen-6-yl N,N-dimethyl-beta-alaninate hydrochloride (1:1)
• (3R-(3-Alpha,4A-Beta,5-Beta,6-Beta,6A-Alpha,10-Alpha,10A-Beta,10B-Alpha))-Id
• 1H-Naphtho[2,1-b]pyran, β-alanine deriv.
• 6-(3-Dimethylaminopropionyl)forskolin hydrochloride
• Adehl
• Adehl (TN)
• Beta-Alanine,N,N-Dimethyl-,5-(Acetyloxy)-3-Ethenyldodecahydro-10,10B-Dihydrox
• Colforsin dapropate hydrochloride
• Colforsindapropatehydrochloride
• N,N-Dimethyl-(3R,4aR,5S,6aS,10S,10aR,10bS)-5-(acetyloxy)-3-ethenyldodecahydro-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-
• Nkh 477
• Y-3,4A,7,7,10A-Pentamethyl-1-Oxo-1H-Naphtho(2,1-B)Pyran-6-Ylester,Hydrochlor
• β-Alanine, N,N-dimethyl-, (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-(acetyloxy)-3-ethenyldodecahydro-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-1H-naphtho[2,1-b]pyran-6-yl ester, hydrochloride
• β-Alanine, N,N-dimethyl-, (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-(acetyloxy)-3-ethenyldodecahydro-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-1H-naphtho[2,1-b]pyran-6-yl ester, hydrochloride (1:1)

NKH477

CAS: 138605-00-2

Fórmula: C₂₇H₄₄ClNO₈

Pureza: 98%

Peso molecular: 546.0932

Ref: IN-DA01E1RR

NKH477

CAS: 138605-00-2

NKH477

Pureza: ≥98%

Peso molecular: 546.09g/mol

Ref: 54-BUP21855

NKH477

CAS: 138605-00-2

NKH477 (Colforsin dapropate hydrochloride) is a derivative of forskolin with antidepressant activity.

Fórmula: C₂₇H₄₄ClNO₈

Pureza: 98% - 98%

Cor e Forma: Solid

Peso molecular: 546.09

Ref: TM-T16332

NKH 477

Produto Controlado

CAS: 138605-00-2

Fórmula: C₂₇H₄₃NO₈·ClH

Cor e Forma: Neat

Peso molecular: 546.093

Ref: TR-N605000

NKH 477

CAS: 138605-00-2

NKH 477 is a drug that has been shown to increase the amount of calcium in the cytosol of cells. It has been found to be effective at low doses, which may be due to its ability to activate phospholipase C and stimulate the release of calcium from intracellular stores. NKH477 is an analogue of glucagon-like peptide 1 (GLP-1) and has been shown to have similar effects on cardiac muscle, but with less effect on pancreatic beta cells.
The effect of NKH 477 on cardiac muscle was studied in vitro using papillary muscle strips from guinea pig hearts. The drug was shown to cause relaxation of the muscles by stimulating ryanodine receptors, which are responsible for releasing calcium from intracellular stores. This drug may also have potential as a treatment for type 2 diabetes mellitus by activating GLP-1 receptors in the pancreas.

Fórmula: C₂₇H₄₄ClNO₈

Pureza: Min. 95%

Peso molecular: 546.09 g/mol

Ref: 3D-BN178886