CAS 138844-81-2: Ibandronato de sódio

Descrição: Ibandronato de sódio é um composto de bisfosfonato usado principalmente no tratamento e prevenção da osteoporose, particularmente em mulheres pós-menopáusicas. Funciona inibindo a reabsorção óssea mediada por osteoclastos, aumentando assim a densidade mineral óssea e reduzindo o risco de fraturas. A substância é caracterizada por sua alta afinidade pelo hidroxiapatita, o que permite que se ligue efetivamente ao tecido ósseo. Ibandronato de sódio é tipicamente administrado por via oral ou intravenosa, com sua farmacocinética influenciada por fatores como ingestão de alimentos e função renal. O composto é conhecido por sua relativamente longa meia-vida no osso, permitindo uma dosagem menos frequente em comparação com outros bisfosfonatos. Efeitos colaterais comuns podem incluir distúrbios gastrointestinais, dor musculoesquelética e, em casos raros, osteonecrose da mandíbula. Devido ao seu mecanismo de ação, Ibandronato de sódio também está sendo investigado para aplicações potenciais em outras condições envolvendo o metabolismo ósseo. Como com qualquer medicamento, é essencial considerar contraindicações e interações com outros medicamentos ao prescrever ou usar este composto.

Fórmula: C₉H₂₃NO₇P₂·Na

InChI: InChI=1S/C9H23NO7P2.Na/c1-3-4-5-7-10(2)8-6-9(11,18(12,13)14)19(15,16)17;/h11H,3-8H2,1-2H3,(H2,12,13,14)(H2,15,16,17);

Chave InChI: InChIKey=WQVSHLXLXKMYEW-UHFFFAOYSA-N

SMILES: [Na].O=P(O)(O)C(O)(CCN(C)CCCCC)P(=O)(O)O

Sinónimos:

• (1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid monosodium salt
• BM 21.0955Na
• Bm 21.0955
• Bondronat
• Bondronat, (1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid sodium
• Bondronate
• Boniva
• Bonviva
• Ibandronate sodium
• Phosphonic acid, P,P′-[1-hydroxy-3-(methylpentylamino)propylidene]bis-, sodium salt (1:1)
• Phosphonic acid, [1-hydroxy-3-(methylpentylamino)propylidene]bis-, monosodium salt
• Sodium Hydrogen {1-Hydroxy-3-[Methyl(Pentyl)Amino]-1-Phosphonopropyl}Phosphonate
• sodium [1-hydroxy-1-(hydroxy-oxido-phosphoryl)-3-(methyl-pentyl-amino) propyl]phosphonic acid
• sodium [1-hydroxy-1-(hydroxy-oxido-phosphoryl)-3-(methyl-pentyl-amino) propyl]phosphonic acid
• (1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid monosodium salt
• Ibandronate Sodium (anhydrous)
• sodium [1-hydroxy-1-(hydroxy-oxido-phosphoryl)-3-(methyl-pentyl-amino) propyl]phosphonic acid
• (1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid monosodium salt
• sodium [1-hydroxy-1-(hydroxy-oxido-phosphoryl)-3-(methyl-pentyl-amino) propyl]phosphonic acid
• (1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid monosodium salt
• sodium [1-hydroxy-1-(hydroxy-oxido-phosphoryl)-3-(methyl-pentyl-amino) propyl]phosphonic acid
• (1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid monosodium salt
• sodium [1-hydroxy-1-(hydroxy-oxido-phosphoryl)-3-(methyl-pentyl-amino) propyl]phosphonic acid
• (1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid monosodium salt
• sodium [1-hydroxy-1-(hydroxy-oxido-phosphoryl)-3-(methyl-pentyl-amino) propyl]phosphonic acid
• (1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid monosodium salt
• sodium [1-hydroxy-1-(hydroxy-oxido-phosphoryl)-3-(methyl-pentyl-amino) propyl]phosphonic acid
• (1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid monosodium salt
• sodium [1-hydroxy-1-(hydroxy-oxido-phosphoryl)-3-(methyl-pentyl-amino) propyl]phosphonic acid
• (1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid monosodium salt
• sodium [1-hydroxy-1-(hydroxy-oxido-phosphoryl)-3-(methyl-pentyl-amino) propyl]phosphonic acid
• (1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid monosodium salt
• sodium [1-hydroxy-1-(hydroxy-oxido-phosphoryl)-3-(methyl-pentyl-amino) propyl]phosphonic acid
• (1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid monosodium salt
• sodium [1-hydroxy-1-(hydroxy-oxido-phosphoryl)-3-(methyl-pentyl-amino) propyl]phosphonic acid
• (1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid monosodium salt
• sodium [1-hydroxy-1-(hydroxy-oxido-phosphoryl)-3-(methyl-pentyl-amino) propyl]phosphonic acid
• (1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid monosodium salt
• sodium [1-hydroxy-1-(hydroxy-oxido-phosphoryl)-3-(methyl-pentyl-amino) propyl]phosphonic acid
• (1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid monosodium salt
• sodium [1-hydroxy-1-(hydroxy-oxido-phosphoryl)-3-(methyl-pentyl-amino) propyl]phosphonic acid
• (1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid monosodium salt
• sodium [1-hydroxy-1-(hydroxy-oxido-phosphoryl)-3-(methyl-pentyl-amino) propyl]phosphonic acid
• (1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid monosodium salt
• sodium [1-hydroxy-1-(hydroxy-oxido-phosphoryl)-3-(methyl-pentyl-amino) propyl]phosphonic acid
• (1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid monosodium salt
• sodium [1-hydroxy-1-(hydroxy-oxido-phosphoryl)-3-(methyl-pentyl-amino) propyl]phosphonic acid
• (1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid monosodium salt
• sodium [1-hydroxy-1-(hydroxy-oxido-phosphoryl)-3-(methyl-pentyl-amino) propyl]phosphonic acid
• (1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid monosodium salt
• sodium [1-hydroxy-1-(hydroxy-oxido-phosphoryl)-3-(methyl-pentyl-amino) propyl]phosphonic acid
• (1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid monosodium salt
• sodium [1-hydroxy-1-(hydroxy-oxido-phosphoryl)-3-(methyl-pentyl-amino) propyl]phosphonic acid
• (1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid monosodium salt
• sodium [1-hydroxy-1-(hydroxy-oxido-phosphoryl)-3-(methyl-pentyl-amino) propyl]phosphonic acid
• (1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid monosodium salt
• sodium [1-hydroxy-1-(hydroxy-oxido-phosphoryl)-3-(methyl-pentyl-amino) propyl]phosphonic acid
• (1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid monosodium salt
• sodium [1-hydroxy-1-(hydroxy-oxido-phosphoryl)-3-(methyl-pentyl-amino) propyl]phosphonic acid
• (1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid monosodium salt

Ibandronate sodium

CAS: 138844-81-2

Ibandronate sodium (Boniva) is a synthetic nitrogen-containing bisphosphonate, used for the treatment of osteoporosis.

• Fórmula: C₉H₂₂NNaO₇P₂
• Pureza: 98% - 98.13%
• Cor e Forma: Solid
• Peso molecular: 341.21

Phosphonic acid, P,P'-[1-hydroxy-3-(methylpentylamino)propylidene]bis-, sodium salt (1:1)

CAS: 138844-81-2

• Fórmula: C₉H₂₂NNaO₇P₂
• Pureza: 90%
• Cor e Forma: Solid
• Peso molecular: 341.2108

Ibandronate Sodium Salt

CAS: 138844-81-2

• Fórmula: C₉H₂₂NO₇P₂·Na
• Cor e Forma: White To Off-White Solid
• Peso molecular: 318.23 22.99

Sodium Ibandronate

CAS: 114084-78-5 138844-81-2

• Fórmula: C₉H₂₂NNaO₇P₂
• Pureza: >90.0%(T)
• Cor e Forma: White to Almost white powder to crystal
• Peso molecular: 341.21

Ibandronate Sodium Salt

CAS: 138844-81-2

Applications Ibandronate Sodium Salt is an inhibitor of farnesyl diphosphate synthase. References 1. Han, J. …

• Fórmula: C₉H₂₂NO₇P₂·Na
• Cor e Forma: Off-White
• Peso molecular: 341.211

Ibandronate sodium

CAS: 138844-81-2

Farnesyl pyrophosphate synthase inhibitor

• Fórmula: C₉H₂₂NNaO₇P₂
• Pureza: Min. 95%
• Cor e Forma: White To Off-White Solid
• Peso molecular: 341.21 g/mol