CAS 139290-65-6

(R)-(+)-ALFA-(2,3-DIMETOXIFENIL)-1-[2-(4-FLUOROFENIL)ETIL]-4-PIPERIDINA METANOL

Descrição:

(R)-(+)-ALFA-(2,3-DIMETOXIFENIL)-1-[2-(4-FLUOROFENIL)ETIL]-4-PIPERIDINA METANOL, com número CAS 139290-65-6, é um composto químico caracterizado por sua complexa estrutura molecular, que inclui um anel de piperidina e múltiplos substituintes aromáticos. Este composto é tipicamente classificado como um derivado de piperidina e pode exibir propriedades associadas à atividade do sistema nervoso central, dada a presença da moiety de piperidina. A presença do átomo de flúor no grupo fenila pode influenciar suas propriedades farmacológicas, potencialmente aumentando a lipofilicidade e alterando a afinidade de ligação aos receptores. O grupo metanol sugere o potencial para ligações de hidrogênio, o que pode afetar a solubilidade e a reatividade. Além disso, a estereoquímica indicada pela configuração (R) implica arranjos espaciais específicos que podem impactar significativamente a atividade biológica e as interações com alvos biológicos. No geral, as características estruturais únicas deste composto sugerem aplicações potenciais em química medicinal, particularmente no desenvolvimento de agentes terapêuticos. No entanto, estudos detalhados seriam necessários para elucidar completamente suas propriedades e usos potenciais.

Fórmula: C₂₂H₂₈FNO₃

InChI: InChI=1/C22H28FNO3/c1-26-20-5-3-4-19(22(20)27-2)21(25)17-11-14-24(15-12-17)13-10-16-6-8-18(23)9-7-16/h3-9,17,21,25H,10-15H2,1-2H3

Chave InChI: InChIKey=HXTGXYRHXAGCFP-OAQYLSRUSA-N

SMILES: [C@H](O)(C1=C(OC)C(OC)=CC=C1)C2CCN(CCC3=CC=C(F)C=C3)CC2

Sinónimos:

• (+)-Mdl 100907
• (+)-a-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol
• (2,3-Dimethoxyphenyl){1-[2-(4-Fluorophenyl)Ethyl]Piperidin-4-Yl}Methanol
• (R)-(2,3-Dimethoxyphenyl)-[1-[2-(4-fluorophenyl)ethyl]piperidin-4-yl]methanol
• (aR)-a-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol
• 4-Piperidinemethanol, 1-[2-(4-Fluorophenyl)Ethyl]-Alpha-(2,3-Dimethoxyphenyl)-, (Alphar)
• 4-Piperidinemethanol, α-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-, (R)-
• 4-Piperidinemethanol, α-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-, (αR)-
• M 100907
• Mdl100907
• R-Mdl 100907
• Volinanserin
• (R)-(+)-ALPHA-(2,3-DIMETHOXYPHENYL)-1-[2-(4-FLUORO-PHENYL)ETHYL]-4-PIPERIDINE METHANOL
• MDL-100907(Volinanserin)
• MDL100907 tartrate salt
• Volinanserin Hydrochloride Salt
• (aR)-a-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol Hydrochloride
• (R)-(+)-(-(2,3-Dimethoxyphenyl)-1-[2-(4-fluoro-phenyl)ethyl]-4-piperidine methanol
• MDL100907-L-tartrate
• (R)-(2,3-dimethoxyphenyl)(1-(4-fluorophenethyl)piperidin-4-yl)methanol
• (+)-a-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol Hydrochloride
• 4-Piperidinemethanol, 1-[2-(4-fluorophenyl)ethyl]-(-(2,3-dimethoxyphenyl)-, ((R), (R,R)-tartrate
• 4-Piperidinemethanol, 1-[2-(4-fluorophenyl)ethyl]-(-(2,3-dimethoxyphenyl)-, ((R)
• (+)-α-(2,3-DiMethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidineMethanol Hydrochloride
• (R)-(+)-a-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-pipidinemethanol
• (R)-(+)-(-(2,3-Dimethoxyphenyl)-1-[2-(4-fluoro-phenyl)ethyl]-4-piperidine methanol (R,R)-tartrate

4-Piperidinemethanol, α-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-, (αR)-

CAS: 139290-65-6

Fórmula: C₂₂H₂₈FNO₃

Pureza: 99%

Cor e Forma: Solid

Peso molecular: 373.4610

Ref: IN-DA001AP3

Volinanserin

CAS: 139290-65-6

Volinanserin

Pureza: ≥98%

Peso molecular: 373.46g/mol

Ref: 54-BUP13230

Volinanserin

CAS: 139290-65-6

Volinanserin (MDL100907) is a potent 5-HT2 receptor antagonist with a Ki of 0.36 nM, 300x selective over 5-HT1c, alpha-1, and sigma receptors.

Fórmula: C₂₂H₂₈FNO₃

Pureza: 98.94% - 99.95%

Cor e Forma: Solid

Peso molecular: 373.46

Ref: TM-T5389

Volinanserin HCl

CAS: 139290-65-6

Fórmula: C₂₂H₂₈FNO₃·HCl

Peso molecular: 373.47 36.46

Ref: 4Z-V-100001

(R)-(2,3-Dimethoxyphenyl)(1-(4-fluorophenethyl)piperidin-4-yl)methanol

CAS: 139290-65-6

Pureza: 95.0%

Peso molecular: 373.4679870605469

Ref: 10-F436152

Volinanserin Hydrochloride Salt

CAS: 139290-65-6

Applications A serotonin 5-HT2A receptor antagonist. Used as potential controls in various biological studies.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Wong, D.F., et al.: Science, 226, 1393 (1984), Blin, J., et al.: Eur. J. Pharmacol., 147, 73 (1988), Kehne, J.H., et al.: J. Pharmacol. Exp. Ther., 277, 968 (1996),

Fórmula: C₂₂H₂₈FNO₃

Cor e Forma: Neat

Peso molecular: 373.46

Ref: TR-V755000

MDL 100907

CAS: 139290-65-6

Selective antagonist of the serotonin receptors 5-HT2A with subnanomolar affinity. The compound has clozapine-like anti-psychotic properties and more favourable CNS safety profile than traditional anti-psychotics. MDL 100907 has been used in studies on antisocial behaviour in mice and shown that the blockage of 5-HT2A receptors leads to decreased post-traumatic aggression and bradycardia.

Fórmula: C₂₂H₂₈FNO₃

Pureza: Min. 95%

Cor e Forma: White Solid

Peso molecular: 373.46 g/mol

Ref: 3D-FV28720