CAS 139481-59-7: Candesartana

Descrição: Candesartana é um antagonista do receptor da angiotensina II usado principalmente no tratamento da hipertensão e insuficiência cardíaca. Pertence à classe de medicamentos conhecidos como sartanas, que atuam bloqueando a ação da angiotensina II, um hormônio que contrai os vasos sanguíneos e aumenta a pressão arterial. A fórmula química de Candesartana é C24H20N6O3, e apresenta uma estrutura de bifenila com um anel de tetrazol, contribuindo para suas propriedades farmacológicas. Candesartana é tipicamente administrado por via oral e é conhecido por sua longa meia-vida, permitindo a dosagem uma vez ao dia. É bem absorvido no trato gastrointestinal, embora sua biodisponibilidade possa ser afetada pela ingestão de alimentos. Efeitos colaterais comuns podem incluir tontura, fadiga e hipotensão, enquanto efeitos adversos graves podem envolver comprometimento renal e hipercalemia. Candesartana é contraindicado na gravidez devido ao potencial dano ao feto. No geral, é um medicamento eficaz para o manejo da hipertensão e para melhorar os resultados cardiovasculares em pacientes com insuficiência cardíaca.

Fórmula: C₂₄H₂₀N₆O₃

InChI: InChI=1S/C24H20N6O3/c1-2-33-24-25-20-9-5-8-19(23(31)32)21(20)30(24)14-15-10-12-16(13-11-15)17-6-3-4-7-18(17)22-26-28-29-27-22/h3-13H,2,14H2,1H3,(H,31,32)(H,26,27,28,29)

Chave InChI: InChIKey=HTQMVQVXFRQIKW-UHFFFAOYSA-N

SMILES: O=C(O)C1=CC=CC=2N=C(OCC)N(C21)CC=3C=CC(=CC3)C=4C=CC=CC4C5=NN=NN5

Sinónimos:

• (1,1'-biphenyl)-4-yl)methyl)-
• (4S)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
• 1-((2′-(1H-Tetrazol-5-yl)-[1,1′-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylic acid
• 1-{[(cyclohexyloxy)carbonyl]oxy}ethyl 2-ethoxy-1-{[2'-(2H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-benzimidazole-7-carboxylate
• 1H-Benzimidazole-7-carboxylic acid
• 1H-Benzimidazole-7-carboxylic acid, 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-
• 1H-Benzimidazole-7-carboxylic acid, 2-ethoxy-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-
• 2-Ethoxy-1-([4-[2-(1H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl]methyl)-1H-1,3-benzodiazole-7-carboxylic acid
• 2-Ethoxy-1-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-7-benzimidazolecarboxy
• 2-Ethoxy-1-[[2'-(1H-tetrazol-5-yl)-1,1'-biphenyl-4-yl]methyl]-7-benzimidazolecarboxylic acid
• 2-Ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H-benzimidazole-7-carboxylic acid
• 2-Ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazol-7-carboxylic acid
• 2-Ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylic acid
• 2-Ethoxy-1-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylic acid
• 2-Ethoxy-3-[[4-[2-(1H-tetrazol-5-yl)phenyl]phenyl]methyl]-3H-benzoimidazole-4-carboxylic acid
• 2-ethoxy-1-((2'-(1H-tetrazol-5-yl)
• 2-ethoxy-1-({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl)-1H-benz
• 2-ethoxy-1-{[2'-(2H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-benzimidazole-7-carboxylic acid
• 3-[[2'-(1H-Tetrazol-5-yl)biphenyl-4-yl]methyl]-2-ethoxy-3H-benzimidazole-4-carboxylic acid
• Blopress
• Blopress (TN)
• C07468
• Candesartan (USAN)
• Candesartan M1
• Candesartan [USAN:INN]
• Chebi:3347
• Cv 11974
• D00522
• imidazole-7-carboxylic acid
• lic acid
• 2-Ethoxy-1-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-7-benzimidazolecarboxy
• lic acid
• 2-ethoxy-1-((2'-(1H-tetrazol-5-yl)
• (1,1'-biphenyl)-4-yl)methyl)-
• Candesartan
• 2-ethoxy-1-({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl)-1H-benz
• imidazole-7-carboxylic acid
• 2-ethoxy-1-((2'-(1H-tetrazol-5-yl)
• (1,1'-biphenyl)-4-yl)methyl)-
• 2-ethoxy-1-({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl)-1H-benz
• imidazole-7-carboxylic acid
• 2-Ethoxy-1-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-7-benzimidazolecarboxy
• lic acid
• 2-ethoxy-1-({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl)-1H-benz
• imidazole-7-carboxylic acid
• 2-Ethoxy-1-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-7-benzimidazolecarboxy
• lic acid
• 2-ethoxy-1-((2'-(1H-tetrazol-5-yl)
• (1,1'-biphenyl)-4-yl)methyl)-
• 2-Ethoxy-1-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-7-benzimidazolecarboxy
• lic acid
• 2-ethoxy-1-({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl)-1H-benz
• imidazole-7-carboxylic acid
• 2-ethoxy-1-((2'-(1H-tetrazol-5-yl)
• (1,1'-biphenyl)-4-yl)methyl)-
• 2-ethoxy-1-((2'-(1H-tetrazol-5-yl)
• (1,1'-biphenyl)-4-yl)methyl)-
• 2-ethoxy-1-({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl)-1H-benz
• imidazole-7-carboxylic acid
• 2-Ethoxy-1-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-7-benzimidazolecarboxy
• lic acid
• 2-Ethoxy-1-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-7-benzimidazolecarboxy
• lic acid
• 2-ethoxy-1-((2'-(1H-tetrazol-5-yl)
• (1,1'-biphenyl)-4-yl)methyl)-
• 2-ethoxy-1-({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl)-1H-benz
• imidazole-7-carboxylic acid
• 2-Ethoxy-1-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-7-benzimidazolecarboxy
• lic acid
• 2-ethoxy-1-({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl)-1H-benz
• imidazole-7-carboxylic acid
• 2-ethoxy-1-((2'-(1H-tetrazol-5-yl)
• (1,1'-biphenyl)-4-yl)methyl)-
• 2-ethoxy-1-({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl)-1H-benz
• imidazole-7-carboxylic acid
• 2-Ethoxy-1-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-7-benzimidazolecarboxy
• lic acid
• 2-ethoxy-1-((2'-(1H-tetrazol-5-yl)
• (1,1'-biphenyl)-4-yl)methyl)-
• 2-ethoxy-1-({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl)-1H-benz
• imidazole-7-carboxylic acid
• 2-Ethoxy-1-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-7-benzimidazolecarboxy
• lic acid
• 2-ethoxy-1-((2'-(1H-tetrazol-5-yl)
• (1,1'-biphenyl)-4-yl)methyl)-
• 2-ethoxy-1-({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl)-1H-benz
• imidazole-7-carboxylic acid
• 2-Ethoxy-1-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-7-benzimidazolecarboxy
• lic acid
• 2-ethoxy-1-((2'-(1H-tetrazol-5-yl)
• (1,1'-biphenyl)-4-yl)methyl)-
• 2-ethoxy-1-({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl)-1H-benz
• imidazole-7-carboxylic acid
• 2-Ethoxy-1-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-7-benzimidazolecarboxy
• lic acid
• 2-ethoxy-1-((2'-(1H-tetrazol-5-yl)
• (1,1'-biphenyl)-4-yl)methyl)-
• 2-Ethoxy-1-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-7-benzimidazolecarboxy
• lic acid
• 2-ethoxy-1-((2'-(1H-tetrazol-5-yl)
• (1,1'-biphenyl)-4-yl)methyl)-
• 2-ethoxy-1-({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl)-1H-benz
• imidazole-7-carboxylic acid
• 2-Ethoxy-1-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-7-benzimidazolecarboxy
• lic acid
• 2-ethoxy-1-({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl)-1H-benz
• imidazole-7-carboxylic acid
• 2-ethoxy-1-((2'-(1H-tetrazol-5-yl)
• (1,1'-biphenyl)-4-yl)methyl)-
• 2-ethoxy-1-({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl)-1H-benz
• imidazole-7-carboxylic acid
• 2-Ethoxy-1-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-7-benzimidazolecarboxy
• lic acid
• 2-ethoxy-1-((2'-(1H-tetrazol-5-yl)
• (1,1'-biphenyl)-4-yl)methyl)-
• 2-ethoxy-1-({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl)-1H-benz
• imidazole-7-carboxylic acid
• 2-ethoxy-1-((2'-(1H-tetrazol-5-yl)
• (1,1'-biphenyl)-4-yl)methyl)-
• 2-Ethoxy-1-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-7-benzimidazolecarboxy
• lic acid
• 2-ethoxy-1-({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl)-1H-benz
• imidazole-7-carboxylic acid
• 2-Ethoxy-1-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-7-benzimidazolecarboxy
• lic acid
• 2-ethoxy-1-((2'-(1H-tetrazol-5-yl)
• (1,1'-biphenyl)-4-yl)methyl)-
• 2-Ethoxy-1-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-7-benzimidazolecarboxy
• lic acid
• 2-ethoxy-1-({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl)-1H-benz
• imidazole-7-carboxylic acid
• 2-ethoxy-1-((2'-(1H-tetrazol-5-yl)
• (1,1'-biphenyl)-4-yl)methyl)-
• 2-ethoxy-1-({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl)-1H-benz
• imidazole-7-carboxylic acid
• 2-ethoxy-1-((2'-(1H-tetrazol-5-yl)
• (1,1'-biphenyl)-4-yl)methyl)-
• 2-Ethoxy-1-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-7-benzimidazolecarboxy
• lic acid
• 2-ethoxy-1-((2'-(1H-tetrazol-5-yl)
• (1,1'-biphenyl)-4-yl)methyl)-
• 2-Ethoxy-1-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-7-benzimidazolecarboxy
• lic acid
• 2-ethoxy-1-({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl)-1H-benz
• imidazole-7-carboxylic acid

Candesartan, 98%

CAS: 139481-59-7

Candesartan is a selective AT1 (angiotensin II receptor 1) antagonist. Antagonism of angiotensin receptors inhibits …

• Fórmula: C₂₄H₂₀N₆O₃
• Pureza: 98%
• Cor e Forma: White to pale cream, Powder
• Peso molecular: 440.45

Candesartan Cilexetil Related Compound G (1-{[2'-(1H-Tetrazol-5-yl)biphenyl-4-yl]methyl}-2-ethoxybenzimidazole-7-carboxylic acid)

CAS: 139481-59-7

Heterocyclic compounds with nitrogen hetero-atom(s) only, aromatic or modified aromatic, nesoi

• Fórmula: C₂₄H₂₀N₆O₃
• Cor e Forma: White Powder
• Peso molecular: 440.15969

Candesartan

CAS: 139481-59-7

• Fórmula: C₂₄H₂₀N₆O₃
• Pureza: 95%
• Cor e Forma: Solid
• Peso molecular: 440.454

Candesartan

CAS: 139481-59-7

Candesartan (CV 11974) is an angiotensin II receptor blocker used widely in the therapy of …

• Fórmula: C₂₄H₂₀N₆O₃
• Pureza: 98.30% - 99.55%
• Cor e Forma: Colorless Solid Crystalline
• Peso molecular: 440.47

Candesartan

CAS: 139481-59-7

• Pureza: ≥98%
• Peso molecular: 440.47g/mol

Candesartan

CAS: 139481-59-7

• Fórmula: C₂₄H₂₀N₆O₃
• Peso molecular: 440.45

Candesartan (Candesartan Cilexetil EP Impurity G, Candesartan Cilexetil USP Related Compound G)

CAS: 139481-59-7

• Fórmula: C₂₄H₂₀N₆O₃
• Cor e Forma: White To Off-White Solid
• Peso molecular: 440.46

2-ethoxy-1-{[2'-(1H-1,2,3,4-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl}-1H-1,3-benzodiazole-7-carboxylic acid

CAS: 139481-59-7

• Pureza: 99%
• Peso molecular: 440.463012695313

2-Ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H-benzimidazole-7-carboxylic Acid (Candesartan)

CAS: 139481-59-7

• Fórmula: C₂₄H₂₀N₆O₃
• Cor e Forma: Neat
• Peso molecular: 440.45

Candesartan 100 µg/mL in Acetonitrile:Methanol

CAS: 139481-59-7

• Fórmula: C₂₄H₂₀N₆O₃
• Cor e Forma: Single Solution
• Peso molecular: 440.45

Candesartan

CAS: 139481-59-7

• Fórmula: C₂₄H₂₀N₆O₃
• Cor e Forma: Neat
• Peso molecular: 440.45

Candesartan

CAS: 139481-59-7

Impurity Candesartan Cilexetil EP Impurity G Applications Candesartan (Candesartan Cilexetil EP Impurity G) is an …

• Fórmula: C₂₄H₂₀N₆O₃
• Cor e Forma: Off White
• Peso molecular: 440.45

Candesartan - Bio-X ™

CAS: 139481-59-7

Candesartan is a drug that belongs to the class of angiotensin II receptor antagonists and …

• Fórmula: C₂₄H₂₀N₆O₃
• Pureza: Min. 95%
• Cor e Forma: Powder
• Peso molecular: 440.45 g/mol

Candesartan

CAS: 139481-59-7

Angiotensin II receptor I antagonist; anti-hypertensive

• Fórmula: C₂₄H₂₀N₆O₃
• Pureza: Min. 98 Area-%
• Cor e Forma: White Powder
• Peso molecular: 440.46 g/mol