
CAS 139755-91-2
:O-Desethyl Sildenafil
CAS:O-Desethyl sildenafil is a metabolite of the phosphodiesterase 5 (PDE5) inhibitor sildenafil .1Fórmula:C20H26N6O4SCor e Forma:SolidPeso molecular:446.53Sildenafil EP Impurity C (O-Desethyl Sildenafil)
CAS:Fórmula:C20H26N6O4SCor e Forma:White To Off-White SolidPeso molecular:446.535-[2-Hydroxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl]-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one (Desethylsildenafil)
CAS:Produto ControladoFórmula:C20H26N6O4SCor e Forma:NeatPeso molecular:446.52Desethyl Sildenafil
CAS:Produto ControladoImpurity Sildenafil EP Impurity C
Applications Desethyl Sildenafil (Sildenafil EP Impurity C) is a metabolite of Sildenafil (S435000), an orally active selective type 5 cGMP phosphodiesterase inhibitor.
References Terrett, N.K., et al.: Bioorg. Med. Chem. Lett., 6, 1819 (1996); Goldstein, I., et al.: N. Engl. J. Med., 338, 1397 (1998)Fórmula:C20H26N6O4SCor e Forma:WhitePeso molecular:446.52Desethyl sildenafil
CAS:Sildenafil is a phosphodiesterase type 5 (PDE5) inhibitor that is used to treat erectile dysfunction. The compound is not considered hazardous and does not have any known environmental effects. It is primarily metabolized by the liver and excreted in urine. Metabolites are inactive and do not contribute to the pharmacological effect of sildenafil. Sildenafil has been detected in wastewater, although at very low concentrations due to its high water solubility. Matrix effects, such as adsorption onto particulates, can also affect the concentration of active drug in wastewater samples. There are various analytical methods available for measuring sildenafil in wastewater including headspace gas chromatography (HSGC), liquid chromatography-mass spectrometry (LCMS), and liquid chromatography-tandem mass spectrometry (LC-MS/MS). Histology studies have shown that sildenafil does not accumulate in tissues or
Fórmula:C20H26N6O4SPureza:Min. 95%Peso molecular:446.52 g/mol







