CAS 1400-61-9

Nistatina

Descrição:

Nistatina é um medicamento antifúngico usado principalmente para tratar infecções fúngicas, particularmente aquelas causadas por espécies de Candida. É um antibiótico macrolídeo polieno derivado da bactéria Streptomyces noursei. Nistatina exibe uma cor amarelada característica e é solúvel em dimetilsulfóxido (DMSO) e levemente solúvel em água, o que limita seu uso sistêmico devido à potencial toxicidade. O mecanismo de ação envolve a ligação ao ergosterol, um componente chave das membranas celulares fúngicas, levando à formação de poros que interrompem a integridade da membrana e resultam na morte celular. Nistatina é tipicamente administrado topicamente ou por via oral, dependendo do tipo e localização da infecção, e é comumente usado no tratamento de candidíase oral e infecções cutâneas. Embora geralmente bem tolerado, pode causar irritação local ou reações alérgicas em alguns indivíduos. Seu uso é contraindicado em pacientes com hipersensibilidade conhecida ao medicamento ou seus componentes. No geral, Nistatina continua sendo um agente importante no manejo de infecções fúngicas superficiais.

Fórmula: Unspecified

InChI: InChI=1/C18H28O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h3-10H,2,11-17H2,1H3,(H,19,20)

SMILES: CCC=CC=CC=CC=CCCCCCCCC(=O)O

Sinónimos:

• (21E,23E,25E,27E,31E,33E)-20-[(3-amino-3,6-dideoxy-D-mannopyranosyl)oxy]-4,6,8,11,12,16,18,36-octahydroxy-35,37,38-trimethyl-2,14-dioxooxacyclooctatriaconta-21,23,25,27,31,33-hexaene-17-carboxylic acid
• 33-[(3-Amino-3,6-Dideoxyhexopyranosyl)Oxy]-3,4,7,9,11,17,37-Heptahydroxy-15,16,18-Trimethyl-13-Oxo-14,39-Dioxabicyclo[33.3.1]Nonatriaconta-19,21,25,27,29,31-Hexaene-36-Carboxylic Acid
• <span class="text-smallcaps">L</span>-Nystatin
• Biofanal
• Candio-Hermal
• Ceratocide
• Diastatin
• Flagystatin
• Fungicidin
• L-Nystatin
• Moronal (antibiotic)
• Myconystatin
• Mycostatin
• Mycostatin Pastilles
• Mykostatyna
• N-[1-hydroxy-1-(4-hydroxyphenyl)propan-2-yl]-4-phenylbutan-2-aminium chloride
• Nilstat
• Nistatin
• Nistatina
• Nyotran
• Nysfungin
• Nystacid
• Nystan
• Nystatin
• Nystatin Suspension Cell Culture Tested
• Nystatin, Streptomyces noursei, Sterile, TC Grade
• Nystatine
• Nystavescent
• Nystex
• Nystop
• O-V Statin
• Octadeca-9,11,13,15-Tetraenoic Acid

Nystatin

CAS: 1400-61-9

Nystatin, 1400-61-9, is a macrolide complex with antifungal and antibiotic properties which exhibits activity against several species of yeast. Learn more.

Fórmula: C₄₇H₇₅NO₁₇

Cor e Forma: White to pale cream, Powder

Peso molecular: 926.11

Ref: 02-J62486

NYSTATIN CRS

CAS: 1400-61-9

NYSTATIN CRS

Fórmula: C₁₈H₂₈O₂

Peso molecular: 276.4137

Ref: 41-N1400000

NYSTATIN RS

CAS: 1400-61-9

NYSTATIN RS

Fórmula: C₁₈H₂₈O₂

Peso molecular: 276.4137

Ref: 41-ICRS0369

THIRD INTERNATIONAL STANDARD FOR NYSTATIN

CAS: 1400-61-9

THIRD INTERNATIONAL STANDARD FOR NYSTATIN

Fórmula: C₁₈H₂₈O₂

Peso molecular: 276.4137

Ref: 41-ISA_29384

Nystatin

CAS: 1400-61-9

Aminoglycoside antibiotics

Fórmula: C₄₇H₇₅NO₁₇

Cor e Forma: Yellow Light Tan Powder

Peso molecular: 925.5035

Ref: 45-1477003

Nystatin

CAS: 1400-61-9

Fórmula: C₄₇H₇₅NO₁₇

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 926.0949

Ref: IN-DA001BY5

Nystatin

CAS: 1400-61-9

Fórmula: C₄₇H₇₅NO₁₇

Cor e Forma: Yellow Solid

Peso molecular: 926.11

Ref: 4Z-N-082001

Nystatin hydrate

CAS: 1400-61-9

Fórmula: C₄₇H₇₅NO₁₇·xH₂O

Pureza: ≥ 4500U/mg (dried basis)

Cor e Forma: Yellow to brown-yellow powder

Peso molecular: 926.09 (anhydrous)

Ref: 7W-GA3995

Nystatin

CAS: 1400-61-9

Nystatin

Pureza: ≥60%

Peso molecular: 926.1g/mol

Ref: 54-BUP18530

Nystatin hydrate, 4400 U/mg, USP grade

CAS: 1400-61-9

Fórmula: C₄₇H₇₅NO₁₇·xH₂O

Pureza: ≤ 4.0%

Cor e Forma: Yellow to dark yellow or tan powder

Peso molecular: 926.09 (anhydrous)

Ref: 7W-GP7660

Nystatin dihydrate

CAS: 1400-61-9

Nystatin dihydrate

Fórmula: C₄₇H₇₅NO₁₇·2H₂O

Pureza: By hplc: 91 area-% (Typical Value in Batch COA)

Cor e Forma: yellow powder

Peso molecular: 962.12546g/mol

Ref: 54-BIN0138

Nystatin

Produto Controlado

CAS: 1400-61-9

Fórmula: C₄₇H₇₅NO₁₇

Cor e Forma: Neat

Peso molecular: 926.09

Ref: 04-C15661000

Nystatin

CAS: 1400-61-9

Nystatin (Fungicidin) is a topical and oral antifungal agent with activity against many species of yeast and candida albicans, which is used largely to treat

Fórmula: C₄₇H₇₅NO₁₇

Pureza: 69.55% - 99.86%

Cor e Forma: Yellow Suspension

Peso molecular: 926.1

Ref: TM-T1678

Nystatin

CAS: 1400-61-9

Applications Polyene antifungal antibiotic complex containing 3 biologically active components, A1, A2, A3. Increases the permeability of the cell membrane of sensitive fungi by binding to sterols. Cell culture tested. Growth promotant.Nystatin A1 is shown.
References Brautaset, T., et al.: Chem. Biol., 7, 395 (2000), Brautaset, T., et al.: J. Biol. Chem., 278, 14913 (2003), Bruheim, P., et al.: Antimicrob. Agents Chemother., 48, 4120 (2004), Scott, L., et al.: Drugs, 67, 269 (2007),

Fórmula: C₄₇H₇₅NO₁₇

Cor e Forma: Neat

Peso molecular: 926.09

Ref: TR-N926000

Nystatin

CAS: 1400-61-9

Nystatin is an antifungal compound, which is produced by the bacterium *Streptomyces noursei*. It functions by binding to ergosterol, a crucial component of fungal cell membranes, creating pores that lead to increased membrane permeability. This disruption results in the leakage of essential cellular components, ultimately causing cell death.

Fórmula: C₄₇H₇₅NO₁₇

Pureza: Min. 85 Area-%

Cor e Forma: Powder

Peso molecular: 926.09 g/mol

Ref: 3D-MM31116

Nystatin (Mycostatin) Solution (10000U/ml) for cell culture, Endotoxin (BET) 10.0EU/ml

CAS: 1400-61-9

Fórmula: C₄₇H₇₅NO₁₇

Cor e Forma: Pale yellow to yellow, Suspension

Peso molecular:  926.09

Ref: SR-17565

Nystatin (Mycostatin) for cell culture, 85%, Endotoxin (BET) 0.05EU/mg

CAS: 1400-61-9

Fórmula: C₄₇H₇₅NO₁₇

Pureza: min. 85%

Cor e Forma: Yellow to slightly brownish, Powder

Peso molecular: 926.09

Ref: SR-16828

iso-Nystatin

CAS: 1400-61-9

iso-Nystatin is an antifungal compound, which is derived from the bacterium *Streptomyces noursei*. This specific strain of actinobacteria produces polyene macrolide antifungals, and iso-Nystatin is a derivative that exhibits similar bioactivity as its parent compound, Nystatin. Its mode of action is based on binding ergosterol, a crucial component of fungal cell membranes. This binding disrupts the membrane's structural integrity, inducing pore formation, which leads to ion leakage and ultimately cell lysis and fungal cell death.

Fórmula: C₄₇H₇₅NO₁₇

Pureza: Min. 95%

Peso molecular: 926.09 g/mol

Ref: 3D-FN177277