CAS 1404456-53-6

2-Thiophenecarboxamide, 5-[[(5-chloro-2-methyl-3-pyridinyl)amino]methyl]-N-[(1S)-1-(cyclopentylmethyl)-2-(cyclopropylamino)-2-oxoethyl]-

CAS: 1404456-53-6

Fórmula: C₂₃H₂₉ClN₄O₂S

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 461.0200

Ref: IN-DA001CFZ

(S)-5-(((5-Chloro-2-Methylpyridin-3-Yl)Amino)Methyl)-N-(3-Cyclopentyl-1-(Cyclopropylamino)-1-Oxopropan-2-Yl)Thiophene-2-Carboxamide

CAS: 1404456-53-6

(S)-5-(((5-Chloro-2-Methylpyridin-3-Yl)Amino)Methyl)-N-(3-Cyclopentyl-1-(Cyclopropylamino)-1-Oxopropan-2-Yl)Thiophene-2-Carboxamide

Pureza: 98%

Peso molecular: 461.02g/mol

Ref: 54-OR1023795

GSK 2830371

CAS: 1404456-53-6

GSK 2830371

Pureza: ≥98%

Peso molecular: 461.02g/mol

Ref: 54-BUP06501

GSK 2830371

CAS: 1404456-53-6

GSK 2830371 is an orally active, allosteric Wip1 phosphatase inhibitor with IC50 of 6 nM.

Fórmula: C₂₃H₂₉ClN₄O₂S

Pureza: 99.85%

Cor e Forma: Solid

Peso molecular: 461.02

Ref: TM-T6521

GSK 2830371

Produto Controlado

CAS: 1404456-53-6

Fórmula: C₂₃H₂₉ClN₄O₂S

Cor e Forma: Neat

Peso molecular: 461.02

Ref: TR-G797475

GSK 2830371-d4

CAS: 1404456-53-6

GSK 2830371-d4 is a chemical compound that inhibits the growth of breast cancer cells. It has been shown to inhibit the proliferation of Her2+ breast cancer cells and induce apoptosis, which leads to long-term efficacy in inhibiting tumor growth. GSK 2830371-d4 also inhibits the activation of HER2+ breast cancer cells by suppressing the mitochondrial membrane potential, thereby inhibiting cell proliferation. This drug is also effective against carcinoma cell lines and shows no acute toxicities at low doses. GSK 2830371-d4 may be a potential biomarker for identifying patients with increased risk of developing breast cancer due to its ability to inhibit the activation of HER2+ breast cancer cells by suppressing the mitochondrial membrane potential.

Fórmula: C₂₃H₂₅D₄ClN₄O₂S

Pureza: Min. 95%

Peso molecular: 465.04 g/mol

Ref: 3D-EGC45653