CAS 1405-89-6

Bacitracina zinco

Descrição:

Bacitracina zinco é um composto antibiótico que é uma mistura complexa de polipeptídeos cíclicos produzidos pela bactéria Bacillus subtilis. É utilizado principalmente por suas propriedades antibacterianas, particularmente contra bactérias Gram-positivas. A forma de sal de zinco melhora sua estabilidade e solubilidade, tornando-o adequado para várias aplicações, incluindo pomadas tópicas e medicina veterinária. Bacitracina zinco atua inibindo a síntese da parede celular bacteriana, o que leva à lise celular e morte. É frequentemente utilizado em combinação com outros antibióticos para ampliar seu espectro de atividade. O composto é geralmente considerado seguro para uso tópico, mas pode causar reações alérgicas em alguns indivíduos. Em termos de propriedades físicas, Bacitracina zinco é tipicamente um pó branco a off-white que é solúvel em água e tem um sabor ligeiramente amargo. Seu uso é regulamentado, e é importante seguir as diretrizes para prevenir o desenvolvimento de resistência a antibióticos.

Fórmula: Unspecified

InChI: InChI=1/C66H103N17O16S.Zn/c1-9-35(6)52(69)66-81-48(32-100-66)63(97)76-43(26-34(4)5)59(93)74-42(22-23-50(85)86)58(92)83-53(36(7)10-2)64(98)75-40-20-15-16-25-71-55(89)46(29-49(68)84)78-62(96)47(30-51(87)88)79-61(95)45(28-39-31-70-33-72-39)77-60(94)44(27-38-18-13-12-14-19-38)80-65(99)54(37(8)11-3)82-57(91)41(21-17-24-67)73-56(40)90;/h12-14,18-19,31,33-37,40-48,52-54H,9-11,15-17,20-30,32,67,69H2,1-8H3,(H2,68,84)(H,70,72)(H,71,89)(H,73,90)(H,74,93)(H,75,98)(H,76,97)(H,77,94)(H,78,96)(H,79,95)(H,80,99)(H,82,91)(H,83,92)(H,85,86)(H,87,88);/q;+2/p-2/t35?,36-,37-,40-,41+,42+,43-,44+,45-,46-,47+,48?,52?,53-,54-;/m0./s1

SMILES: CCC(C)C(C1=NC(CS1)C(=NC(CC(C)C)C(=NC(CCC(=O)O)C(=NC(C(C)CC)C(=NC1CCCCN=C(C(CC(=N)O)N=C(C(CC(=O)O)N=C(C(Cc2cnc[nH]2)N=C(C(Cc2ccccc2)N=C(C(C(C)CC)N=C(C(CCCN)N=C1O)O)O)O)O)O)O)O)O)O)O)N.[Zn]

Sinónimos:

• Albac
• Bacifarmin
• Bacifarmin-zinc
• Baciferm
• Baciferm PB
• Bacitracin Zinc
• Bacitracin zinc salt
• L-isoleucinamide, N-[[2-(1-amino-2-methylbutyl)-4,5-dihydro-4-thiazolyl]carbonyl]-L-leucyl-D-alpha-glutamyl-N-[(3S,6R,9S,12R,15S,18R,21S)-3-(2-amino-2-oxoethyl)-18-(3-aminopropyl)-6-(carboxymethyl)-9-(1H-imidazol-5-ylmethyl)-15-(1-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-12-(phenylmethyl)-1,4,7,10,13,16,19-heptaazacyclopentacos-21-yl]-, zinc salt (1:1)
• Noptracin
• St 56
• zinc N-{[2-(1-amino-2-methylbutyl)-4,5-dihydro-1,3-thiazol-4-yl]carbonyl}-L-leucyl-5-oxidanidyl-5-oxidanylidene-D-norvalyl-N-{(3S,6R,9S,12R,15S,18R,21S)-3-(2-amino-2-oxoethyl)-18-(3-aminopropyl)-12-benzyl-6-(carboxylatomethyl)-9-(1H-imidazol-5-ylmethyl)-15-[(1S)-1-methylpropyl]-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclopentacosan-21-yl}-L-isoleucinamide

BACITRACIN FOR SYSTEM SUITABILITY CRS

CAS: 1405-89-6

BACITRACIN FOR SYSTEM SUITABILITY CRS

Fórmula: C₆₆H₁₀₃N₁₇O₁₆SZn

Cor e Forma: White. Yellow. Powder.

Peso molecular: 1488.101

Ref: 41-Y0001867

SECOND INTERNATIONAL STANDARD FOR BACITRACIN

CAS: 1405-89-6

SECOND INTERNATIONAL STANDARD FOR BACITRACIN

Ref: 41-ISA_62_003

BACITRACIN ZINC CRS

CAS: 1405-89-6

BACITRACIN ZINC CRS

Fórmula: C₆₆H₁₀₃N₁₇O₁₆SZn

Cor e Forma: White. Yellow. Powder.

Peso molecular: 1488.101

Ref: 41-B0100000

Bacitracin Zinc

CAS: 1405-89-6

Antibiotics nesoi

Fórmula: C₆₆H₁₀₁N₁₇O₁₆SZn(BacitracinAZinc)C₆₅H₉₉N₁₇O₁₆SZn(BacitracinB₁B₂orB₃Zinc)

Cor e Forma: White Tan Light Brown Powder

Peso molecular: 1483.66243

Ref: 45-1048007

Bacitracin (zinc)

CAS: 1405-89-6

Fórmula: C₆₆H₁₀₁N₁₇O₁₆SZn

Cor e Forma: Solid

Peso molecular: 1486.0574

Ref: IN-DA001CJR

Bacitracin zinc salt

CAS: 1405-89-6

Fórmula: C₆₆H₁₀₁N₁₇O₁₆SZn

Pureza: ≥ 65.0U/mg (dried basis)

Cor e Forma: Off-white to light-yellow powder

Peso molecular: 1486.07

Ref: 7W-GA1078

Bacitracin Zinc

CAS: 1405-89-6

Fórmula: C₆₆H₁₀₁N₁₇O₁₆S·Zn

Peso molecular: 1420.70 65.38

Ref: 4Z-PB-073022

Bacitracin Zinc

CAS: 1405-89-6

Bacitracin Zinc is a dephosphorylated disruptor of C55-isoprene pyrophosphate that inhibits Tyr cleavage in Met-enkephalin with an IC50 of 10 μM.

Fórmula: C₆₆H₁₀₁N₁₇O₁₆SZn

Pureza: 63.98%

Cor e Forma: Light-Colored Free-Flowing Powders

Peso molecular: 1486.07

Ref: TM-T2208

Bacitracin Zinc (>80%)

Produto Controlado

CAS: 1405-89-6

Applications Bacitracin is a peptide antibiotic effective against gram-postive bacteria. Bacitracin is an inhibitor of peptidoglycan synthesis. Bacitracin disrupts bacterial cell wall synthesis by inhibiting dephosphorylation of lipid pyrophosphate. Bacitracin also strongly inhibits proline endopeptidase from human muscle.
References Ward, J.B. et al.: Biochem. J., 141, 227 (1974); Anastasi, A. et al.: Biochem. J., 290, 601 (1993); Daly, D.J. et al.: Biochem. Soc. Trans., 13, 1161 (1985); Weinberg, E.D. et al.: Antibiot. Ber., 90, (1967);

Fórmula: C₆₅H₉₉N₁₇O₁₆S·Zn

Pureza: >80%

Cor e Forma: Light Yellow To Off-White

Peso molecular: 1472.06

Ref: TR-B106505

Bacitracin zinc

CAS: 1405-89-6

Bacitracin zinc is a biocide that is used for the treatment of infectious diseases in animals. It has neurotrophic and polyvinyl pyrrolidone properties, which inhibit bacterial growth by preventing protein synthesis. Bacitracin zinc can be used to treat infections caused by bacteria that are resistant to penicillin, tetracycline, erythromycin, and other antibiotics. This drug can be formulated as a suspension or an emulsion in a polymeric matrix with undamaged polymer chains to provide stabilization against hydrolysis.

Fórmula: C₆₆H₁₀₁N₁₇O₁₆SZn

Pureza: Min. 95%

Cor e Forma: Powder

Peso molecular: 1,486.06 g/mol

Ref: 3D-FB37622