CAS 141595-53-1

N,N-hexametilenocarbamoil-leu-N-*formil-D-trp-D-

Descrição:

N,N-hexametilenocarbamoilo-leu-N-formilo-D-triptofano (CAS 141595-53-1) é um composto sintético que pertence à classe de derivados peptídicos. Apresenta uma cadeia de hexametileno que conecta um grupo carbamoilo a um resíduo de leucina, juntamente com uma porção de D-triptofano formilado. Esta estrutura sugere que pode exibir propriedades típicas de peptídeos, como atividade biológica potencial e interações com receptores ou enzimas específicos. A presença do grupo formilo pode influenciar sua reatividade e solubilidade, enquanto a configuração do aminoácido D pode afetar sua estabilidade e resistência à degradação enzimática. O composto provavelmente será de interesse na pesquisa bioquímica, particularmente em estudos relacionados à síntese de peptídeos, design de fármacos ou como um potencial agente terapêutico. Suas características específicas, como solubilidade, ponto de fusão e atividade biológica, exigiriam investigação empírica para entender completamente seu comportamento em vários ambientes.

Fórmula: C₃₆H₄₄N₆O₆

InChI: InChI=1/C36H44N6O6/c1-23(2)17-29(40-36(48)41-15-9-3-4-10-16-41)33(44)38-30(19-25-21-42(22-43)32-14-8-6-12-27(25)32)34(45)39-31(35(46)47)18-24-20-37-28-13-7-5-11-26(24)28/h5-8,11-14,20-23,29-31,37H,3-4,9-10,15-19H2,1-2H3,(H,38,44)(H,39,45)(H,40,48)(H,46,47)/t29-,30+,31+/m0/s1

Sinónimos:

• N-(azepan-1-ylcarbonyl)-L-leucyl-1-formyl-D-tryptophyl-D-tryptophan
• Bq-610

BQ-610

CAS: 141595-53-1

BQ-610 is a very potent ET-A receptor antagonist which is about 30000 times more selective for ET-A receptors than for ET-B receptors. Furthermore, it has been found that BQ-610 strongly antagonizes ET-1 induced concentration in porcine coronary artery with a pA₂ value of 8.2.

Fórmula: C₃₆H₄₄N₆O₆

Pureza: > 95%

Peso molecular: 656.78

Ref: 01-4034542

D-Tryptophan, N-[(hexahydro-1H-azepin-1-yl)carbonyl]-L-leucyl-1-formyl-D-tryptophyl-

CAS: 141595-53-1

Fórmula: C₃₆H₄₄N₆O₆

Peso molecular: 656.7712

Ref: IN-DA001GNK

BQ-610

CAS: 141595-53-1

BQ-610 is a drug that has been shown to improve brain functions and energy metabolism. It also inhibits the transmission of pain signals in the mesenteric region of rats by blocking voltage-dependent calcium channels. BQ-610 is found to suppress the production of endothelin-a receptor, which is an important regulator for many diseases such as infectious diseases, hypertension, and other cardiovascular disorders. The drug has also been shown to reduce oxidative stress by inhibiting cell nuclei and reducing inflammation by inhibiting basic protein synthesis. BQ-610 has been shown to be effective against congestive heart failure in rats by increasing blood flow and improving biochemical properties.

Fórmula: C₃₆H₄₄N₆O₆

Pureza: Min. 95%

Peso molecular: 656.79 g/mol

Ref: 3D-PED-3610-PI

BQ-610

CAS: 141595-53-1

BQ-610 is an Endothelin A receptor antagonist.

Fórmula: C₃₆H₄₄N₆O₆

Cor e Forma: Solid

Peso molecular: 656.77

Ref: TM-T70727

BQ-610 Azepane-1-carbonyl-Leu-D-Trp(For)-D-Trp-OH

CAS: 141595-53-1

BQ-610 is a novel peptide that has been shown to reduce the severity of mucosal inflammation in animal models of inflammatory bowel disease. It functions by binding to myofibroblasts, which are cells that produce an extracellular matrix and collagen. BQ-610 also blocks signalling pathways that are responsible for the production of TNF-α, MMP-2, and other molecules involved in the pathogenesis of inflammatory bowel disease. BQ-610 is effective at reducing inflammation in animal models of colitis, but not in human colonic epithelial cells or human colonic tissue.

Fórmula: C₃₆H₄₄N₆O₆

Pureza: Min. 95%

Peso molecular: 656.77 g/mol

Ref: 3D-FB109401