CAS 14197-60-5

Ginsenosídeo Rg3

Descrição:

Ginsenosídeo Rg3 é um composto natural classificado como uma saponina triterpenoide, encontrado principalmente no ginseng, especialmente no Panax ginseng. É conhecido por suas potenciais propriedades farmacológicas, incluindo efeitos anti-inflamatórios, antioxidantes e anticancerígenos. Ginsenosídeo Rg3 existe em duas formas isoméricas, Rg3(S) e Rg3(R), que podem exibir diferentes atividades biológicas. O composto possui uma estrutura molecular complexa caracterizada por uma espinha dorsal semelhante a um esteroide com múltiplos grupos hidroxila, contribuindo para sua solubilidade e reatividade. Ginsenosídeo Rg3 é frequentemente estudado por seu papel na melhoria da função imunológica e seus potenciais efeitos neuroprotetores. Além disso, tem sido investigado por sua capacidade de modular várias vias de sinalização, tornando-se um assunto de interesse tanto na medicina tradicional quanto na farmacologia moderna. Seu perfil de segurança e potencial terapêutico continuam a ser explorados em estudos clínicos e pré-clínicos, destacando sua relevância na saúde e bem-estar.

Fórmula: C₄₂H₇₂O₁₃

InChI: InChI=1S/C42H72O13/c1-21(2)10-9-14-42(8,51)22-11-16-41(7)29(22)23(45)18-27-39(5)15-13-28(38(3,4)26(39)12-17-40(27,41)6)54-37-35(33(49)31(47)25(20-44)53-37)55-36-34(50)32(48)30(46)24(19-43)52-36/h10,22-37,43-51H,9,11-20H2,1-8H3/t22-,23+,24+,25+,26-,27+,28-,29-,30+,31+,32-,33-,34+,35+,36-,37-,39-,40+,41+,42-/m0/s1

Chave InChI: InChIKey=RWXIFXNRCLMQCD-JBVRGBGGSA-N

SMILES: C[C@]12[C@@]3(C)[C@@]([C@@]([C@@](CCC=C(C)C)(C)O)(CC3)[H])([C@H](O)C[C@@]1([C@]4(C)[C@@](CC2)(C(C)(C)[C@@H](O[C@H]5[C@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)[C@@H](O)[C@H](O)[C@@H](CO)O5)CC4)[H])[H])[H]

Sinónimos:

• (20S)-Propanaxadiol
• (2S,3R,4S,5S,6R)-2-[(2R,3R,4S,5S,6R)-4,5-dihydroxy-2-[[(10R,12S,13R,14R,17S)-12-hydroxy-17-[(2R)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,10,13,14-pentamethyl-2,3,5,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-(hydroxymethyl)oxa
• (3Beta,12Beta)-12,20-Dihydroxydammar-24-En-3-Yl 2-O-Beta-D-Glucopyranosyl-Beta-D-Glucopyranoside
• (3β,12β)-12,20-Dihydroxydammar-24-en-3-yl 2-O-β-<span class="text-smallcaps">D</smallcap>-glucopyranosyl-β-<smallcap>D</span>-glucopyranoside
• (3β,12β)-12,20-Dihydroxydammar-24-en-3-yl O-β-<span class="text-smallcaps">D</smallcap>-glucopyranosyl-(1→2)-β-<smallcap>D</span>-glucopyranoside
• (5xi,8xi,9xi,12alpha,14beta,20R)-12,20-dihydroxylanost-24-en-3-yl 2-O-beta-D-glucopyranosyl-beta-D-glucopyranoside
• (8xi,9xi,12alpha,14beta,17alpha)-12-hydroxy-17-[(2S)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,10,14-tetramethylgonan-3-yl 2-O-[3-deoxy-3-(hydroxymethyl)-beta-D-glucopyranosyl]-beta-D-glucopyranoside
• 20(R)-Propanaxadiol
• 20(S)-Ginsenoside-Rg3
• 20(S)-Ginsenoside-Rg₃
• 20(S)-Rg3
• 20S-Ginsenoside Rg3
• 3-O-β-<span class="text-smallcaps">D</smallcap>-Glucopyranosyl-(1→2)-β-<smallcap>D</span>-glucopyranosyldammar-24-ene-3β,12β,20S-triol
• Beta-D-Glucopyranoside,(3-Beta,12-Beta)-12,20-Dihydroxydammar-24-En-3-Yl2-O-B
• Dammar-24-Ene-12-Beta,20-Diol,3-Beta-((2-O-Beta-D-Glucopyranosyl-Beta-D-Gluc
• Dammar-24-ene-12β,20-diol, 3β-[(2-O-β-<span class="text-smallcaps">D</smallcap>-glucopyranosyl-β-<smallcap>D</span>-glucopyranosyl)oxy]-
• Dammar-24-ene-12β,20-diol, 3β-[(2-O-β-D-
• Dammarane, β-<span class="text-smallcaps">D</span>-glucopyranoside deriv.
• Eta-D-Glucopyranosyl-
• Ginsenoside 20-Rg3
• Ginsenoside Rg3s
• Ginsenoside Rg₃
• Opyransoyl)Oxy)-
• S-Ginsenoside Rg₃
• beta-D-Glucopyranoside,(3beta,12beta)-12,20-dihydroxydammar-24-en-3-yl 2-O-beta-D-glucopyranosyl
• β-<span class="text-smallcaps">D</smallcap>-Glucopyranoside, (3β,12β)-12,20-dihydroxydammar-24-en-3-yl 2-O-β-<smallcap>D</span>-glucopyranosyl-
• Dammar-24-ene-12β,20-diol, 3β-[(2-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]-
• Dammarane, β-D-glucopyranoside deriv.
• (3β,12β)-12,20-Dihydroxydammar-24-en-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside

20(S)-Ginsenoside Rg3

CAS: 14197-60-5

Fórmula: C₄₂H₇₂O₁₃

Pureza: >95.0%(HPLC)

Cor e Forma: White to Light yellow powder to crystal

Peso molecular: 785.03

Ref: 3B-G0568

Ginsenoside Rg3

CAS: 14197-60-5

Ginsenoside Rg3 analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Fórmula: C₄₂H₇₂O₁₃

Pureza: (HPLC) ≥98%

Cor e Forma: Powder

Peso molecular: 785.03

Ref: 11-0152S

20(S)-Ginsenoside Rg3

CAS: 14197-60-5

20(S)-Ginsenoside Rg3

Pureza: ≥98%

Peso molecular: 785.01g/mol

Ref: 54-BUP13475

Ginsenoside Rg3

CAS: 14197-60-5

Ginsenoside-Rg3, possess an ability to inhibit the lung metastasis of tumor cells, and the mechanism of their antimetastatic effect is related to inhibition of the adhesion and invasion of tumor cells, and also to anti-angiogenesis activity.

Fórmula: C₄₂H₇₂O₁₃

Pureza: 95%~99%

Cor e Forma: White powder

Peso molecular: 785.025

Ref: BP-BP0666

Ginsenoside Rg3

CAS: 14197-60-5

Fórmula: C₄₂H₇₂O₁₃

Peso molecular: 785.03

Ref: 4Z-G-157004

Ginsenoside Rg3-d6

CAS: 14197-60-5

Fórmula: C₄₂H₆₆D₆O₁₃

Peso molecular: 791.06

Ref: 4Z-G-157008

Ginsenoside Rg3

CAS: 14197-60-5

Fórmula: C₄₂H₇₂O₁₃

Pureza: ≥ 98.0%

Cor e Forma: White to beige powder

Peso molecular: 785.01

Ref: 7W-GC4250

20(S)-Ginsenoside Rg3

CAS: 14197-60-5

20(S)-Ginsenoside Rg3 (Rg3) possess an ability to inhibit the lung metastasis of tumor cells via inhibition of the adhesion and invasion of tumor cells.

Fórmula: C₄₂H₇₂O₁₃

Pureza: 98.11% - 99.93%

Cor e Forma: Solid

Peso molecular: 785.01

Ref: TM-T3402

Ginsenoside rg3

CAS: 14197-60-5

Natural glycoside

Fórmula: C₄₂H₇₂O₁₃

Pureza: ≥ 90.0 % (HPLC)

Cor e Forma: Powder

Peso molecular: 785.03

Ref: 5G-89681

Ginsenoside Rg3

Produto Controlado

CAS: 14197-60-5

Applications Ginsenoside Rg3 shows a synergistic antitumor effect with cisplatin in cisplatin-resistant bladder tumor cell lines and is considered to be an anti-tumor agent.
References Lee, Y; et al.: Onc. Rep., 32, 1803 (2014); Ge, X. et al.: J. Int. Med. Res., 42, 628 (2014)

Fórmula: C₄₂H₇₂O₁₃

Cor e Forma: Neat

Peso molecular: 785.01

Ref: TR-G387590

(20S)-Ginsenoside Rg3

CAS: 14197-60-5

(20S)-Ginsenoside Rg3 is a bioactive saponin compound derived from the root of Panax ginseng. It is a naturally occurring component in ginseng, a traditional medicinal plant extensively studied for its diverse health benefits. The mode of action of (20S)-Ginsenoside Rg3 primarily involves the modulation of cellular pathways, such as the inhibition of tumor growth through apoptosis induction and anti-angiogenic effects. Additionally, it interacts with various signaling molecules, leading to its anti-inflammatory, antioxidant, and neuroprotective activities.

Fórmula: C₄₂H₇₂O₁₃

Pureza: Min. 98 Area-%

Cor e Forma: White Powder

Peso molecular: 785.01 g/mol

Ref: 3D-OG09291