CAS 1421-65-4

L-3,4-dihidroxifenilalanina metil*éster hidrocloridrato

Descrição:

L-3,4-diidroxifenilalanina metila cloridrato, comumente referido como metila L-DOPA, é um derivado do aminoácido L-DOPA, que é um precursor de neurotransmissores como a dopamina. Este composto é caracterizado por seus grupos hidroxila no anel benzênico, que contribuem para sua reatividade e solubilidade em solventes polares. A presença do grupo éster metílico aumenta sua lipofilicidade em comparação com L-DOPA, potencialmente afetando sua absorção e biodisponibilidade. Como sal cloridrato, é tipicamente mais estável e solúvel em soluções aquosas, tornando-o adequado para várias aplicações farmacêuticas. L-DOPA e seus derivados são estudados principalmente por seu papel no tratamento de condições como a doença de Parkinson, onde a deficiência de dopamina é uma preocupação significativa. As propriedades farmacológicas do composto, incluindo sua capacidade de atravessar a barreira hematoencefálica, fazem dele um foco crítico em neurofarmacologia. Além disso, sua síntese e caracterização são de interesse em química medicinal para o desenvolvimento de novos agentes terapêuticos.

Fórmula: C₁₀H₁₄ClNO₄

InChI: InChI=1/C10H13NO4.ClH/c1-15-10(14)7(11)4-6-2-3-8(12)9(13)5-6;/h2-3,5,7,12-13H,4,11H2,1H3;1H

Chave InChI: InChIKey=WFGNJLMSYIJWII-FJXQXJEOSA-N

SMILES: C([C@@H](C(OC)=O)N)C1=CC(O)=C(O)C=C1.Cl

Sinónimos:

• (S)-Dopa methyl ester hydrochloride
• (S)-Methyl 2-amino-3-(3,4-dihydroxyphenyl)propanoate hydrochloride
• 3,4-Dihydroxyphenyl-<span class="text-smallcaps">L</span>-alanine methyl ester hydrochloride
• 3-Hydroxy-<span class="text-smallcaps">L</span>-tyrosine methyl ester hydrochloride
• <span class="text-smallcaps">L</span>-Dopa methyl ester hydrochloride
• <span class="text-smallcaps">L</span>-Tyrosine, 3-hydroxy-, methyl ester, hydrochloride
• <span class="text-smallcaps">L</span>-Tyrosine, 3-hydroxy-, methyl ester, hydrochloride (1:1)
• Alanine, 3-(3,4-dihydroxyphenyl)-, methyl ester, hydrochloride
• Alanine, 3-(3,4-dihydroxyphenyl)-, methyl ester, hydrochloride, <span class="text-smallcaps">L</span>-
• L-3,4-Dihydroxyphenylalanine methyl ester hydrochloride
• L-DOPA Me ester hydrochloride
• Levodopa methyl ester hydrochloride
• Methyl 3-Hydroxytyrosinate
• Methyl 3-Hydroxytyrosinate Hydrochloride (1:1)
• Methyl <span class="text-smallcaps">L</span>-3-(3,4-dihydroxyphenyl)alaninate hydrochloride
• St 41769
• methyl 3-hydroxy-L-tyrosinate hydrochloride (1:1)
• L-Tyrosine, 3-hydroxy-, methyl ester, hydrochloride
• L-Tyrosine, 3-hydroxy-, methyl ester, hydrochloride (1:1)
• 3,4-Dihydroxyphenyl-L-alanine methyl ester hydrochloride
• Alanine, 3-(3,4-dihydroxyphenyl)-, methyl ester, hydrochloride, L-
• L-3,4-Dihydroxyphenylalanine methyl ester
• Methyl L-3-(3,4-dihydroxyphenyl)alaninate hydrochloride
• -3,4-Dihydroxyphenylalanine methyl ester hydrochloride
• Dihydroxyphenylalanine Methyl ester hydrochloride
• TIANFUCHEM--1421-65-4--High purity L-3,4-DIHYDROXYPHENYLALANINE METHYL ESTER HYDROCHLORIDE in stock
• Nsc295453
• LevoMet Hydrochloride
• L-3,4-DIHYDROXYPHENYLALANINE METHYLESTER HYDROCHLO
• 3-Hydroxy-L-tyrosine Methyl Ester Hydrochloride
• L-3,4-Dihydroxyphenylalanine Methyl Ester Hydrochloride,>95%
• Melevodopa Hydrochloride
• H-PHE(3,4-DI-HYDROXY)-OME HCL
• METHYL L-DOPA HYDROCHLORIDE
• 3,4-
• Methyl 3-Hydroxy-L-tyrosine Hydrochloride
• [(2S)-3-(3,4-dihydroxyphenyl)-1-methoxy-1-oxopropan-2-yl]azanium
• 3-hydroxy- L-Tyrosine methyl ester, hydrochloride (1:1)
• Levodopa Impurity 10
• Melevodopa
• L-DOPA Methyl Ester Hydrochloride
• -Methyl 2-amino-3-(3,4-dihydroxyphenyl)
• methyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate hydrochloride
• H-TYR(3-HYDROXY)-OME HCL
• methyldopa hydrochloride
• 3-(3,4-Dihydroxyphenyl)alanine Methyl Ester Hydrochloride
• 2-Amino-3-(3,4-dihydroxyphenyl)-propanoic acid methylester hydrochloride
• L
• 4-DIHYDROXYPHENYLALANINE METHYL ESTER HYDROCHLORIDE
• 3,4-DIHYDROXY PHENYLALANINE METHYL ESTER HYDROCHLORIDE
• -
• 3,4-Dihydroxy-L-phenylalanine Methyl Ester Hydrochloride
• (S)-2-Amino-3-(3,4-dihydroxyphenyl)propanoic acid hydrochloride
• L-3,4-dihydroxyphenylalanine methyl*ester hydroch
• Dopamine, methyl ester

L-Dopa Methyl Ester Hydrochloride

CAS: 1421-65-4

Fórmula: C₁₀H₁₃NO₄·HCl

Pureza: >98.0%(T)(HPLC)

Cor e Forma: White to Light yellow powder to crystal

Peso molecular: 247.68

Ref: 3B-D6060

L-Tyrosine, 3-hydroxy-, methyl ester, hydrochloride (1:1)

CAS: 1421-65-4

Fórmula: C₁₀H₁₄ClNO₄

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 247.6755

Ref: IN-DA001HT2

L-3,4-Dihydroxyphenylalanine Methyl Ester Hydrochloride

CAS: 1421-65-4

L-3,4-Dihydroxyphenylalanine Methyl Ester Hydrochloride

Pureza: 98%

Peso molecular: 247.68g/mol

Ref: 54-OR1013624

L-3,4-Dihydroxyphenylalanine methyl ester hydrochloride

CAS: 1421-65-4

Fórmula: C₁₀H₁₃NO₄·HCl

Pureza: ≥ 98.0%

Cor e Forma: Conflicting attributes defined

Peso molecular: 247.68

Ref: 7W-GK2381

Levodopa Methyl Ester Hydrochloride

CAS: 1421-65-4

Cor e Forma: Neat

Ref: 86-MM0262.18

L-DOPA methyl ester (hydrochloride)

CAS: 1421-65-4

L-DOPA methyl ester (LDME) is an agonist of dopamine D1 receptor.

Fórmula: C₁₀H₁₄ClNO₄

Pureza: 98.69% - 99.81%

Cor e Forma: White Solid

Peso molecular: 247.675

Ref: TM-T7654

L-DOPA Methyl Ester Hydrochloride

Produto Controlado

CAS: 1421-65-4

Applications L-DOPA Methyl Ester Hydrochloride is a selective Dopamine D1 receptor agonist (1,2,3).
References (1) Astradsson, A., et al.: Neurobiol. Dis., 35, 348 (2009)(2) Garcia-Molina, F., et al.: J. Agric. Food Chem., 57, 1143 (2009) (3) Giorgioni, G., et al.: Bioorg. Med. Chem., 18, 1834 (2010)

Fórmula: C₁₀H₁₃NO₄·ClH

Cor e Forma: Neat

Peso molecular: 247.68

Ref: TR-D533770

L-DOPA methyl ester hydrochloride

Produto Controlado

CAS: 1421-65-4

L-DOPA methyl ester hydrochloride is a form of L-dopa that is used to treat Parkinson's disease. It is a prodrug of L-dopa, which has been shown to have a pharmacokinetic profile similar to that of levodopa. L-DOPA methyl ester hydrochloride is administered orally and is released slowly into the blood stream over time. This drug has been shown to interact with other drugs, such as antidepressants and antipsychotics, through its effects on neurotransmitters. In addition, this drug may cause locomotor activity in animals and can cause an increase in levels of dehydroascorbic acid in patients with chronic oral administration.

Fórmula: C₁₀H₁₃NO₄•HCl

Pureza: Min. 96 Area-%

Cor e Forma: Powder

Peso molecular: 247.68 g/mol

Ref: 3D-FD22596

(S)-Methyl 2-amino-3-(3,4-dihydroxyphenyl)propanoate hydrochloride

CAS: 1421-65-4

Fórmula: C₁₀H₁₄ClNO₄

Pureza: 98%

Cor e Forma: Liquid, No data available.

Peso molecular: 247.68

Ref: 10-F223023