CAS 142217-77-4
:(1S,2S,3S,5S)-5-(2-Amino-6-(benzyloxi)-9H-purina-9-il)-3-(benzyloxi)-2-(benzyloximetil)ciclopentanol
Descrição:
A substância química com o nome "(1S,2S,3S,5S)-5-(2-Amino-6-(benzyloxi)-9H-purina-9-il)-3-(benzyloxi)-2-(benzyloximetil)ciclopentanol" e número CAS "142217-77-4" é um composto orgânico complexo caracterizado por seus grupos multifuncionais e estereoquímica. Apresenta um núcleo de ciclopentanol, que é um álcool cíclico de cinco membros, e está substituído por múltiplos grupos benzyloxi, aumentando sua lipofilicidade e potencial atividade biológica. A presença de um grupo amino e um derivado de purina sugere que este composto pode exibir propriedades relevantes para a química dos ácidos nucleicos ou servir como um potencial agente farmacêutico. A estereoquímica específica indicada pela configuração (1S,2S,3S,5S) implica que o composto tem arranjos espaciais definidos, o que pode influenciar significativamente sua reatividade e interação com alvos biológicos. No geral, a complexidade estrutural deste composto e seus grupos funcionais sugerem aplicações potenciais em química medicinal, particularmente no desenvolvimento de terapias direcionadas a processos relacionados aos ácidos nucleicos.
Fórmula:C32H33N5O4
InChI:InChI=1/C32H33N5O4/c33-32-35-30-28(31(36-32)41-19-24-14-8-3-9-15-24)34-21-37(30)26-16-27(40-18-23-12-6-2-7-13-23)25(29(26)38)20-39-17-22-10-4-1-5-11-22/h1-15,21,25-27,29,38H,16-20H2,(H2,33,35,36)/t25-,26+,27+,29+/m1/s1
Sinónimos:- (1S,2S,3S,5S)-5-(2-Amino-6-(benzyloxy)-9H-purin-9-yl)-3-(benzyloxy)-2-(benzyloxymethyl)cydopentanol
- Entecavir intermediate N4
- (1S,2S,3S,5S)-5-(2-amino-6-(benzyloxy)-9H-purin-9-yl)-3-(benzyloxy)-2-((4-methylbenzyloxy)methyl)cyclopentanol
- Ent-4
- Intermediate of Entecavir 2
- (1S,2S,3S,5S)-5-(2-amino-6-(benzyloxyl)-9H-purin-9yl)-3-(benzyloxymethyl)cyclopentanol
- (1S,2S,3S,5S)-5-(2-Amino-6-(benzyloxy)-9H-purin-9-yl)-3-(benzyloxy)-2-(benzyloxymethyl) cyclopentanol
Ordenar por
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7 produtos.
Cyclopentanol, 5-[2-amino-6-(phenylmethoxy)-9H-purin-9-yl]-3-(phenylmethoxy)-2-[(phenylmethoxy)methyl]-, (1S,2S,3S,5S)-
CAS:Fórmula:C32H33N5O4Pureza:98%Cor e Forma:SolidPeso molecular:551.6355(1S,2S,3S,5S)-5-(2-Amino-6-(benzyloxy)-9H-purin-9-yl)-3-(benzyloxy)-2-(benzyloxymethyl)cyclopentanol
CAS:(1S,2S,3S,5S)-5-(2-Amino-6-(benzyloxy)-9H-purin-9-yl)-3-(benzyloxy)-2-(benzyloxymethyl)cyclopentanolPureza:98%(1S,2S,3S,5S)-5-(2-Amino-6-(benzyloxy)-9H-purin-9-yl)-3-(benzyloxy)-2-(benzyloxymethyl)cyclopentanol
CAS:Pureza:97%Peso molecular:551.64697265625(2R,3R,5R)-5-[2-Amino-6-(phenylmethoxy)-9H-purin-9-yl]-3-(phenylmethoxy)-2-[(phenylmethoxy)methyl]-cyclopentanol
CAS:Produto Controlado<p>Applications (2R,3R,5R)-5-[2-Amino-6-(phenylmethoxy)-9H-purin-9-yl]-3-(phenylmethoxy)-2-[(phenylmethoxy)methyl]-cyclopentanol is an intermediate in the preparation of ent-Entecavir (E558905).<br></p>Fórmula:C32H33N5O4Cor e Forma:NeatPeso molecular:551.635(1S,2S,3S,5S)-5-(2-Amino-6-(benzyloxy)-9H-purin-9-yl)-3-(benzyloxy)-2-(benzyloxymethyl)cyclopentanol
CAS:<p>(1S,2S,3S,5S)-5-(2-Amino-6-(benzyloxy)-9H-purin-9-yl)-3-(benzyloxy)-2-(benzyloxymethyl)cyclopentanol is a synthetic compound that is used to treat patients with chronic myeloid leukemia. It has been shown to inhibit tyrosine kinase and interacts with the guanine binding site of the purine nucleoside phosphorylase. This drug also inhibits the enzyme (deoxy)ribonucleotide reductase and competes with adenosine for binding to adenosine receptors. The stereoisomers of this drug are active against chronic myeloid leukemia cells. The S enantiomer is more potent than the R enantiomer and exhibits greater selectivity for leukemic cells than healthy cells. It has also been shown to inhibit nitric oxide synthase and may have anti-</p>Fórmula:C32H33N5O4Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:551.64 g/mol
![Cyclopentanol, 5-[2-amino-6-(phenylmethoxy)-9H-purin-9-yl]-3-(phenylmethoxy)-2-[(phenylmethoxy)met…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA001HZM.jpg&w=3840&q=75)
![(2R,3R,5R)-5-[2-Amino-6-(phenylmethoxy)-9H-purin-9-yl]-3-(phenylmethoxy)-2-[(phenylmethoxy)methyl]…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb%2FA600160.jpg&w=3840&q=75)
