CAS 143491-57-0

emtricitabina

Descrição:

emtricitabina é um medicamento antirretroviral usado principalmente no tratamento da infecção por HIV. Pertence à classe de medicamentos conhecidos como inibidores da transcriptase reversa de nucleosídeos (ITRNs). A fórmula química de emtricitabina é C₁₃H₁₅N₃O₃S, e apresenta um anel de tiofeno, que contribui para suas propriedades únicas. emtricitabina é caracterizado por sua capacidade de inibir a enzima transcriptase reversa, impedindo assim a replicação do vírus. Geralmente é administrado por via oral e é bem absorvido no trato gastrointestinal. O medicamento é conhecido por seu perfil farmacocinético favorável, incluindo uma longa meia-vida, o que permite a dosagem uma vez ao dia. emtricitabina é frequentemente usado em combinação com outros agentes antirretrovirais para aumentar a eficácia e reduzir o risco de resistência. Efeitos colaterais comuns podem incluir distúrbios gastrointestinais e erupções cutâneas, mas geralmente é bem tolerado. Sua eficácia e perfil de segurança o tornaram um componente chave nos regimes de tratamento do HIV em todo o mundo.

Fórmula: C₈H₁₀FN₃O₃S

InChI: InChI=1/C8H10FN3O3S/c9-4-1-12(8(14)11-7(4)10)5-3-16-6(2-13)15-5/h1,5-6,13H,2-3H2,(H2,10,11,14)

Chave InChI: InChIKey=XQSPYNMVSIKCOC-NTSWFWBYSA-N

SMILES: O=C1N([C@H]2O[C@@H](CO)SC2)C=C(F)C(N)=N1

Sinónimos:

• (-)-2',3'-Dideoxy-5-fluoro-3'-thiacytidine
• (-)-2'-Deoxy-5-fluoro-3'-thiacytidine
• (-)-2′,3′-Dideoxy-5-fluoro-3′-thiacytidine
• (-)-Beta-2',3'-Dideoxy-5-Fluoro-3'-Thiacytidine
• (-)-Ftc
• 1,3-Oxathiolane, 2(1H)-pyrimidinone deriv.
• 2(1H)-Pyrimidinone, 4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-
• 2(1H)-Pyrimidinone, 4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-5-oxathiolanyl]-
• 2(1H)-Pyrimidinone, 4-amino-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-, (2R-cis)-
• 4-Amino-5-Fluoro-1-(2-(Hydroxymethyl)-1,3-Oxathiolan-5-Yl)-(2R-Cis)-2(1H)-Pyrimidinone
• 4-Amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone
• 4-amino-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one
• 524W91
• Bw 1592
• Bw 524W91
• Coviracil
• Emitricibatine
• Emitricitabine
• Emtricitabin
• Emtritabine
• Emtriva
• Fumitremorgin C
• Sm-Q
• EMTRICITABINE
• 4-Amino-5-fluoro-1-[(2R,5S)-2-hydroxymethyl)-1,3-oxathiolan-5-yl]-2-(1H-pyrimidinone, (-)-FTC, (-)--2’,3’-Dideoxy-5-fluoro-3’-thiacytidine, 524W91, BW-52491, Coviracil
• 4-Amino-5-fluoro-1-[(2R,5S)-2-hydroxymethyl)-1,3-oxathiolan-5-yl]-2-(1H-pyrimidinone, (-)-FTC, (-)-b-23Dideoxy-5-fluoro-3thiacytidine, 524W91, BW-52491, Coviracil,
• 4-Amino-5-fluoro-1-[(2R,5S)-2-hydroxymethyl)-1,3-oxathiolan-5-yl]-2-(1H-pyrimidinone,(-)-FTC,(-)-b-23Dideoxy-5-flu
• Entricitabine

Emtricitabine-d2,15N

Produto Controlado

CAS: 143491-57-0

Fórmula: C₈D₂H₈F₁₅NN₂O₃S

Cor e Forma: Neat

Peso molecular: 250.252

Ref: TR-E525003

Emtricitabine System Suitability Mixture A (Emtricitabine; 5-epi Emtricitabine)

Produto Controlado

CAS: 143491-57-0, 145986-26-1

Fórmula: MixtureVisitourWebsite

Cor e Forma: Mixture

Peso molecular: Mixture - Visit our Website

Ref: TR-E154580

Emtricitabine (1.0 mg/mL in Methanol)

CAS: 143491-57-0

Fórmula: C₈H₁₀FN₃O₃S

Ref: TR-KIT7760-1ML

Emtricitabine-d2,15N

CAS: 143491-57-0

Emtricitabine-d2,15N is a labelled version of emtricitabine. It is a nucleoside reverse transcriptase inhibitor that inhibits the HIV-1 virus by blocking the activity of the enzyme needed to convert RNA into DNA. This drug also offers long-term efficacy and can be used in combination with other antiretroviral agents including tenofovir alafenamide hemifumarate (TAF) and tenofovir disoproxil fumarate (TDF). The addition of TAF or TDF to emtricitabine-d2,15N provides an active antiretroviral therapy for HIV/AIDS patients. Emtricitabine-d2,15N has shown to reduce viral load significantly in people taking it as part of their treatment regimen.

Fórmula: C₈D₁₀FN₃O₃S

Pureza: Min. 95%

Peso molecular: 257.3 g/mol

Ref: 3D-NE153331

2',3'-Dideoxy-5-fluoro-3'-thiacytidine

CAS: 143491-57-0

Emtricitabine is a nucleoside analog that is an antiviral drug used to treat HIV/AIDS. It is a synthetic nucleoside analog of cytidine, in which the 3' phosphate and 5' hydroxyl groups have been replaced with a fluorine atom and a methoxy group, respectively. Emtricitabine has been shown to inhibit the synthesis of viral DNA by competing for incorporation into the viral DNA strand during the elongation phase of viral replication. Emtricitabine also has anticancer activity, but no other known therapeutic uses.

Fórmula: C₈H₁₀FN₃O₃S

Pureza: Min. 98 Area-%

Cor e Forma: White Off-White Powder

Peso molecular: 247.25 g/mol

Ref: 3D-NC05645