CAS 143824-78-6

Fmoc-L-Trp(Boc)-OH

Descrição:

Fmoc-L-Trp(Boc)-OH, também conhecido como 9-fluorenilmetoxicarbonila-L-triptofano (Boc)-OH, é um aminoácido protegido comumente utilizado na síntese de peptídeos. Apresenta um grupo fluorenilmetoxicarbonila (Fmoc), que serve como um grupo protetor para a funcionalidade amino, permitindo a desproteção seletiva durante a síntese. A presença do grupo Boc (tert-butiloxicarbonila) na cadeia lateral de indol do triptofano melhora ainda mais sua estabilidade e solubilidade em solventes orgânicos, tornando-o adequado para a síntese de peptídeos em fase sólida. Este composto é tipicamente branco a off-white em aparência e é solúvel em solventes orgânicos como dimetilformamida (DMF) e dimetilsulfóxido (DMSO), mas menos solúvel em água. Sua estrutura molecular inclui um esqueleto de triptofano, que contribui para suas propriedades únicas, como fluorescência e a capacidade de participar em interações de empilhamento π-π. Fmoc-L-Trp(Boc)-OH é amplamente utilizado na síntese de peptídeos e proteínas, particularmente em aplicações de pesquisa e farmacêuticas, devido à sua capacidade de facilitar a introdução de resíduos de triptofano em cadeias de peptídeos.

Fórmula: C₃₁H₃₀N₂O₆

InChI: InChI=1S/C31H30N2O6/c1-31(2,3)39-30(37)33-17-19(20-10-8-9-15-27(20)33)16-26(28(34)35)32-29(36)38-18-25-23-13-6-4-11-21(23)22-12-5-7-14-24(22)25/h4-15,17,25-26H,16,18H2,1-3H3,(H,32,36)(H,34,35)/t26-/m0/s1

Chave InChI: InChIKey=ADOHASQZJSJZBT-SANMLTNESA-N

SMILES: C(OC(N[C@@H](CC=1C=2C(N(C(OC(C)(C)C)=O)C1)=CC=CC2)C(O)=O)=O)C3C=4C(C=5C3=CC=CC5)=CC=CC4

Sinónimos:

• (2S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-[1-[(2-methylpropan-2-yl)oxycarbonyl]indol-3-yl]propanoic acid
• 1-(tert-butoxycarbonyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-tryptophan
• 1-[(1,1-Dimethylethoxy)carbonyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-tryptophan
• 3-[(2S)-2-Carboxy-2-[[[(9H-fluoren-9-yl)methoxy]carbonyl]amino]ethyl]indole-1-carboxylic acid tert-butyl ester
• <span class="text-smallcaps">L</span>-Tryptophan, 1-[(1,1-dimethylethoxy)carbonyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
• Fmoc-L-Trp(Boc)-OH
• Fmoc-Trp(Boc)
• Fmoc-Trp(Boc)-OH
• N-alpha-(9-fluorenylmethyloxycarbonyl)-N-in-t-butyl-oxycarbonyl-L-tryptophan
• N-α-Fmoc-N(in)-Boc-L-tryptophan
• 1-[(1,1-Dimethylethoxy)carbonyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-tryptophan

1-Boc-N-Fmoc-L-tryptophan, 97%

CAS: 143824-78-6

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Fórmula: C₃₁H₃₀N₂O₆

Pureza: 97%

Peso molecular: 526.59

Ref: 02-H59663

Fmoc-Trp(Boc)-OH

CAS: 143824-78-6

Sold under license to US Pat. 5,300,651 and EP 0 516 070. The use of this protected tryptophan derivative in Fmoc solid-phase peptide synthesis resulted in an improved yield of the correct product by suppressing side reactions of tryptophan.

Fórmula: C₃₁H₃₀N₂O₆

Pureza: 99.47%

Cor e Forma: White

Peso molecular: 526.59

Ref: 01-4017674

L-Tryptophan, 1-[(1,1-dimethylethoxy)carbonyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-

CAS: 143824-78-6

Fórmula: C₃₁H₃₀N₂O₆

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 526.5797

Ref: IN-DA001IFQ

Fmoc-Trp(Boc)-OH

CAS: 143824-78-6

M03376 - Fmoc-Trp(Boc)-OH

Fórmula: C₃₁H₃₀N₂O₆

Pureza: 95%

Cor e Forma: Solid, Crystalline or Powder

Peso molecular: 526.589

Ref: 10-M03376

Fmoc-Trp(Boc)-OH

CAS: 143824-78-6

Fmoc-Trp(Boc)-OH

Fórmula: C₃₁H₃₀N₂O₆

Pureza: 98%

Cor e Forma: white to light beige powder

Peso molecular: 526.58g/mol

Ref: 54-OR350178

Fmoc-L-Trp(Boc)-OH

CAS: 143824-78-6

Fórmula: C₃₁H₃₀N₂O₆

Peso molecular: 526.59

Ref: 4Z-T-2083

Fmoc-Trp(Boc)-OH

CAS: 143824-78-6

Fórmula: C₃₁H₃₀N₂O₆

Pureza: ≥ 98.0%

Cor e Forma: White to almost white powder

Peso molecular: 526.58

Ref: 7W-GM7354

Fmoc-Trp(Boc)-OH

CAS: 143824-78-6

Fmoc-Trp(Boc)-OH is an amide that has been shown to have the ability to bind to human serum proteins, making it useful in clinical diagnostics. This compound has also been found to be effective against a variety of bacterial strains and fungi. The Fmoc-Trp(Boc)-OH peptide can be synthesized using solid-phase synthesis techniques, which involve attaching amino acid residues to a polymer support. This process is cell specific and allows for the production of peptides with specific sequences. The presence of histidine residues on the side chain of this molecule makes it a good candidate for use in antimicrobial peptides.

Fórmula: C₃₁H₃₀N₂O₆

Pureza: Min. 98 Area-%

Cor e Forma: White Off-White Powder

Peso molecular: 526.58 g/mol

Ref: 3D-FF15878

Fmoc-Trp(Boc)-OH

CAS: 143824-78-6

Fmoc-Trp(Boc)-OH is a building block for the synthesis of peptides and other bioactive molecules. It is used in the synthesis of daptomycin, an antibiotic that is used to treat bacterial infections caused by methicillin-resistant Staphylococcus aureus (MRSA). Fmoc-Trp(Boc)-OH is also used as a synthon in the production of natural products such as kynurenine, which has been shown to have anti-cancer properties.

Fórmula: C₃₁H₃₀N₂O₆

Pureza: Min. 95%

Peso molecular: 526.59 g/mol

Ref: 3D-FLW-1769-PI

Nα-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N1-tert-butoxycarbonyl-L-tryptophan

CAS: 143824-78-6

Fórmula: C₃₁H₃₀N₂O₆

Pureza: >97.0%(HPLC)

Cor e Forma: White to Orange to Green powder to crystal

Peso molecular: 526.59

Ref: 3B-F0507

Fmoc-Trp(Boc)-OH-13C11,15N2

Produto Controlado

CAS: 143824-78-6

Fórmula: C₁₁C₂₀H₃₀₁₅N₂O₆

Cor e Forma: Neat

Peso molecular: 539.486

Ref: TR-F679602