CAS 14459-29-1

Ácido 21H,23H-porfina-2,18-dipropanoico, 7,12-bis(1-hidroxietil)-3,8,13,17-tetrametil-

Descrição:

A substância química conhecida como "Ácido 21H,23H-porfina-2,18-dipropanoico, 7,12-bis(1-hidroxietil)-3,8,13,17-tetrametil-" com o número CAS 14459-29-1 é um derivado complexo de porfirina. As porfirinas são caracterizadas por suas grandes estruturas cíclicas planas compostas por quatro anéis de pirrol interconectados por pontes de metina, que contribuem para sua capacidade de coordenar íons metálicos, tornando-as significativas em sistemas biológicos, particularmente na hemoglobina e na clorofila. Este composto específico apresenta múltiplos grupos funcionais, incluindo ácido propanoico e substituintes hidroxietílicos, que aumentam sua solubilidade e reatividade. A presença de grupos tetrametílicos indica um grau de impedância estérica, potencialmente influenciando suas interações e estabilidade. Esses derivados de porfirina são frequentemente estudados por suas aplicações em terapia fotodinâmica, bem como no desenvolvimento de sensores e catalisadores devido às suas propriedades eletrônicas únicas. No geral, este composto exemplifica a intrincada relação entre estrutura e função na química das porfirinas.

Fórmula: C₃₄H₃₈N₄O₆

InChI: InChI=1S/C34H38N4O6/c1-15-21(7-9-31(41)42)27-14-28-22(8-10-32(43)44)16(2)24(36-28)12-29-34(20(6)40)18(4)26(38-29)13-30-33(19(5)39)17(3)25(37-30)11-23(15)35-27/h11-14,19-20,36-37,39-40H,7-10H2,1-6H3,(H,41,42)(H,43,44)/b23-11-,24-12-,25-11?,26-13-,27-14?,28-14-,29-12?,30-13?

Chave InChI: InChIKey=UJKPHYRXOLRVJJ-CAKLIFEZSA-N

SMILES: C(CC(O)=O)C1=C2C=C3C(CCC(O)=O)=C(C)C(=N3)C=C4NC(=CC5=NC(=CC(N2)=C1C)C(C(C)O)=C5C)C(C(C)O)=C4C

Sinónimos:

• 1,3,5,8-Tetramethyl-2,4-bis(α-hydroxyethyl)porphine-6,7-dipropionic acid
• 2,18-Porphinedipropionic acid, 7,12-bis(1-hydroxyethyl)-3,8,13,17-tetramethyl-
• 7,12-Bis(1-hydroxyethyl)-3,8,13,17-tetramethyl-2,18-porphinedipropionic acid
• 7,12-Bis(1-hydroxyethyl)-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoic acid
• HP
• Haematoporphyrin
• Hematoporfirina
• Hematoporphyrin
• Hematoporphyrin IX
• Hematoporphyrine
• HpIX
• Nsc 267084
• Nsc 59265
• Photodyn
• 3,3'-[7,12-bis(1-hydroxyethyl)-3,8,13,17-tetramethylporphyrin-2,18-diyl]dipropanoic acid
• 21H,23H-Porphine-2,18-dipropanoic acid, 7,12-bis(1-hydroxyethyl)-3,8,13,17-tetramethyl-
• hematoporphyrin free base
• ANTI-HPR antibody produced in mouse
• HematoporphyrineBase
• 7,12-Bis(1-hydroxyethyl)-3,8,13,17-tetramethyl-21H,23H-porphyrin-2,18-dipropionic acid
• 3-[18-(2-carboxyethyl)-7,12-bis(1-hydroxyethyl)-3,8,13,17-tetramethyl-22,23-dihydroporphin-2-yl]propionic acid
• 3-[18-(2-carboxyethyl)-7,12-bis(1-hydroxyethyl)-3,8,13,17-tetramethyl-22,23-dihydroporphyrin-2-yl]propanoic acid
• 7,12-bis(1-hydroxyethyl)-3,8,13,17-tetramethyl-18-porphinedipropionicacid
• hematoporphyrinix
• 1,3,5,8-tetramethyl-2,4-bis(alpha-hydroxyethyl)prophine-6,7-dipropionicacid
• 21h,23h-porphine-2,18-dipropanoicacid,7,12-bis(1-hydroxyethyl)-3,8,13,17-te
• HeMatoporphyrin >=45%
• 8,13-BIS(1-HYDROXYETHYL)-3,7,12,17-TETRAMETHYL-21H,23H-PORPHINE-2,18-DIPROPIONIC ACID
• HEMATOPORPHYRIN IX BASE

21H,23H-Porphine-2,18-dipropanoic acid, 7,12-bis(1-hydroxyethyl)-3,8,13,17-tetramethyl-

CAS: 14459-29-1

Fórmula: C₃₄H₃₈N₄O₆

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 598.6887

Ref: IN-DA001JT2

Hematoporphyrin

CAS: 14459-29-1

Hematoporphyrin is a substrate for affinity chromatography of heme-binding proteins.

Fórmula: C₃₄H₃₈N₄O₆

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 598.69

Ref: TM-T19354

Haematoporphyrin

CAS: 14459-29-1

Haematoporphyrin is a photosensitizing compound derived from heme, which has been modified to enhance its photophysical properties. It interacts with biological tissues through a mechanism involving the production of reactive oxygen species when activated by light of a specific wavelength. This property makes haematoporphyrin particularly effective in photodynamic therapy (PDT).

Fórmula: C₃₄H₃₈N₄O₆

Pureza: Min. 30 Area-%

Cor e Forma: Powder

Peso molecular: 598.69 g/mol

Ref: 3D-FH70390

Hematoporphyrin (Technical Grade, ~30%)

Produto Controlado

CAS: 14459-29-1

Applications Hematoporphyrin (Photodyn, Sensibion) is a porphyrin prepared from hemin. It is a derivative of protoporphyrin IX, where the two vinyl groups have been hydrated (coverted to alcohols). It is used as a photosensitizer in photodynamic therapy. Acetylation of hematoporphyrin followed by hydrolysis of the product of that reaction affords a mixture called hematoporphyrin derivative (HPD), which is also used in photodynamic therapy. Hematoporphyrin has also been used as an antidepressant and antipsychotic since the 1920s.

Fórmula: C₃₄H₃₈N₄O₆

Cor e Forma: Neat

Peso molecular: 598.68

Ref: TR-H245678