CAS 144689-63-4

olmesartana medoxomila

Descrição:

olmesartana medoxomila é um antagonista do receptor de angiotensina II usado principalmente no tratamento da hipertensão. É um pró-fármaco, o que significa que é metabolizado no corpo para sua forma ativa, olmesartana. A substância é caracterizada por sua capacidade de bloquear seletivamente o receptor de angiotensina II tipo 1 (AT1), que desempenha um papel crucial na regulação da pressão arterial e do equilíbrio de fluidos. Quimicamente, olmesartana medoxomila é um pó cristalino branco a off-white que é praticamente insolúvel em água, mas solúvel em solventes orgânicos. Sua fórmula molecular reflete uma estrutura complexa que inclui um grupo bifenila, contribuindo para sua atividade farmacológica. O composto apresenta uma longa meia-vida, permitindo a dosagem uma vez ao dia, e é frequentemente bem tolerado, com um perfil de efeitos colaterais favorável. Além disso, olmesartana medoxomila tem sido associado a efeitos protetores renais, tornando-se uma opção valiosa no manejo de pacientes com hipertensão, particularmente aqueles com condições comórbidas.

Fórmula: C₂₄H₂₆N₆O₃

InChI: InChI=1S/C29H30N6O6/c1-5-8-23-30-25(29(3,4)38)24(27(36)39-16-22-17(2)40-28(37)41-22)35(23)15-18-11-13-19(14-12-18)20-9-6-7-10-21(20)26-31-33-34-32-26/h6-7,9-14,38H,5,8,15-16H2,1-4H3,(H,31,32,33,34)

Chave InChI: InChIKey=UQGKUQLKSCSZGY-UHFFFAOYSA-N

SMILES: C(N1C(C(OCC2=C(C)OC(=O)O2)=O)=C(C(C)(C)O)N=C1CCC)C3=CC=C(C=C3)C4=C(C=CC=C4)C=5NN=NN5

Sinónimos:

• (5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl 4-(1-hydroxy-1-methylethyl)-2-propyl-1-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylate
• (5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl 4-(1-hydroxy-1-methylethyl)-2-propyl-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}imidazaole-5-carboxylate
• (5-Methyl-2-oxo-2H-1,3-dioxol-4-yl)methyl 4-(2-hydroxypropan-2-yl)-2-propyl-1-([4-[2-(1H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl]methyl)-1H-imidazole-5-carboxylate
• (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 4-ethyl-2-propyl-1-{[2'-(2H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-imidazole-5-carboxylate
• (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl.5-(2-hydroxypropan-2-yl)-2-propyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylate
• 1,3-Dioxole, 1H-imidazole-5-carboxylic acid deriv.
• 1H-Imidazole-5-Carboxylic Acid, 4-(1-Hydroxy-1-Methylethyl)-2-Propyl-1-[[2'-(1H-Tetrazol-5-Yl)[1,1'-Biphenyl]-4-Yl]Methyl]-, (5-Methyl-2-Oxo-1,3-Dioxol-4-Yl)Methyl Ester
• 1H-Imidazole-5-carboxylic acid, 4-(1-hydroxy-1-methylethyl)-2-propyl-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester
• 2-Butyl-4-(1-hydroxy-1-methylethyl)-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylic acid (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester
• 4-(1-Hydroxy-1-Methylethyl)-2-Propyl-1-[[2'-(1H-Tetazol-5-Yl)[1,1'-Biphenyl]-4-Yl]Methyl]-1H-Imidazole-5-Carboxylic Acid (5-Methyl-2-Oxo-1,3-Dioxol-4-Yl)Methyl Ester
• 4-(1-Hydroxy-1-Methylethyl)-2-Propyl-1-[[2'-(1H-Tetrazol-5-Yl)[1,1'-Biphenyl]-4-Yl]Methyl]-1H-Imidazole-5-Carboxylic Acid (5-Methyl-2-Oxo-1,3-Dioxol-4-Yl)Methyl Ester
• Angiosartan
• Benicar
• Cs-866
• Medoxomil
• Olmesartan Medoximil
• Olmetec
• Olsertain
• Omst
• Olmesartan medoxomil
• 5-(1-HYDROXY-1-METHYLETHYL)-2-PROPYL-3-[2''-(1H-TETRAZOL-5-YL)-BIPHENYL-4-YLMETHYL]-3H-IMIDAZOLE-4-CARBOXYLIC ACID 5-METHYL-2-OXO-[1,3]DIOXOL-4-YLMETHYL ESTER
• CS-866, 4-(1-Hydroxy-1-methylethyl)-2-propyl-1-[[2(1H-tetazol-5-yl)[1,1biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylic Acid (5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl Ester
• 5-(1-Hydroxy-1-methylethyl)-2-propyl-3-[2'-(1H-tet
• OlmesartanC29H30N6O6
• OLMESARTAN
• 4-(1-Hydroxy-1-methylethyl)-2-propyl-1-[[2'-(1H-tetazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylicacid(5-Methyl-2-oxo-1,3-dioxol-4-yl)methylester

Olmesartan Medoxomil

CAS: 144689-63-4

Fórmula: C₂₉H₃₀N₆O₆

Pureza: >98.0%(T)(HPLC)

Cor e Forma: White to Light yellow powder to crystal

Peso molecular: 558.60

Ref: 3B-O0510

Olmesartan medoxomil

CAS: 144689-63-4

Olmesartan medoxomil

Fórmula: C₂₉H₃₀N₆O₆

Pureza: 99.7%

Cor e Forma: White. To. Light Yellow

Peso molecular: 558.22268

Ref: 47-1173

OLMESARTAN MEDOXOMIL CRS

CAS: 144689-63-4

OLMESARTAN MEDOXOMIL CRS

Fórmula: C₂₉H₃₀N₆O₆

Cor e Forma: Powder

Peso molecular: 558.5851

Ref: 41-Y0001405

OLMESARTAN MEDOXOMIL FOR SYSTEM SUITABILITY CRS

CAS: 144689-63-4

OLMESARTAN MEDOXOMIL FOR SYSTEM SUITABILITY CRS

Fórmula: C₂₉H₃₀N₆O₆

Cor e Forma: Powder

Peso molecular: 558.5851

Ref: 41-Y0001424

Olmesartan Medoxomil

CAS: 144689-63-4

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Fórmula: C₂₉H₃₀N₆O₆

Cor e Forma: White Light Yellow Powder

Peso molecular: 558.22268

Ref: 45-1478367

1H-Imidazole-5-carboxylic acid, 4-(1-hydroxy-1-methylethyl)-2-propyl-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester

CAS: 144689-63-4

Fórmula: C₂₉H₃₀N₆O₆

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 558.5851

Ref: IN-DA001K0D

Olmesartan Medoxomil

CAS: 144689-63-4

Olmesartan Medoxomil (Benicar) is an angiotensin II type 1 receptor blocker that is used to manage hypertension.

Fórmula: C₂₉H₃₀N₆O₆

Pureza: 99.89% - 99.9%

Cor e Forma: White To Off-White Crystalline Powder

Peso molecular: 558.59

Ref: TM-T1518

Olmesartan Medoxomil

CAS: 144689-63-4

Fórmula: C₂₉H₃₀N₆O₆

Cor e Forma: White To Off-White Solid

Peso molecular: 558.60

Ref: 4Z-O-083

Olmesartan Medoxomil

CAS: 144689-63-4

Olmesartan Medoxomil

Pureza: ≥98%

Peso molecular: 558.59g/mol

Ref: 54-BUP15452

Olmesartan Medoxomil

CAS: 144689-63-4

Olmesartan Medoxomil

Pureza: 99%

Peso molecular: 558.59g/mol

Ref: 54-OR1030127

Olmesartan medoxomil

CAS: 144689-63-4

Fórmula: C₂₉H₃₀N₆O₆

Pureza: 98.0 - 102.0 % (dried basis)

Cor e Forma: White to almost white powder

Peso molecular: 558.59

Ref: 7W-GP3934

Olmesartan medoxomil, EP grade

CAS: 144689-63-4

Fórmula: C₂₉H₃₀N₆O₆

Peso molecular: 558.59

Ref: 7W-GP8971

Olmesartan Medoxomil

Produto Controlado

CAS: 144689-63-4

Fórmula: C₂₉H₃₀N₆O₆

Cor e Forma: Neat

Peso molecular: 558.59

Ref: 86-MM1317.00

Olmesartan Medoxomil RS

CAS: 144689-63-4

Cor e Forma: White To Pale Yellow-White Solid Crystalline Powder

Ref: 2K-1034800021

Olmesartan medoxomil

CAS: 144689-63-4

Olmesartan is a drug that belongs to the class of angiotensin II receptor antagonists. It is used for the treatment of high blood pressure, heart failure, and kidney disease. The therapeutic effect of olmesartan can be increased by concomitant use with other drugs if it is being used as a combination therapy. This drug interacts with many other drugs, including diuretics and ACE inhibitors. Drugs that are known to interact with olmesartan include furosemide, hydrochlorothiazide, amiloride, spironolactone, triamterene, chlorothiazide and quinethazone. Blood sampling is often required during therapy in order to monitor the efficacy of this drug.

Fórmula: C₂₉H₃₀N₆O₆

Pureza: Min. 95%

Cor e Forma: White Powder

Peso molecular: 558.59 g/mol

Ref: 3D-IH57934

Olmesartan Medoxomil

Produto Controlado

CAS: 144689-63-4

Applications An angiotensin II receptor antagonist. Used as an anti-hypertensive.
References Yanagisawa, H., et al.: J. Med. Chem., 39, 323 (1996), Puchler, K., et al.: J. Hypertens., 15, 1809 (1997),

Fórmula: C₂₉H₃₀N₆O₆

Cor e Forma: White

Peso molecular: 558.59

Ref: TR-O550000

Olmesartan Medoxomil

CAS: 144689-63-4

Cor e Forma: Neat

Ref: 61-FOR1317.00